Programme

Day 1

• 0815: Registration and coffee
  
• 0830: Primer on TCR science by Pieter Meysman (Belgium)
  
• 0900: Welcome by Pieter Meysman & Benson Ogunjimi
• 0910: Opening keynote presentation by Paul G Thomas (USA) - Deconstructing the form and function of T cell responses to infections and tumors
  

Session 1: TCR theory, data modeling & tools

• 1000: Victor Greiff (Norway) - ​Benchmarking computational adaptive immune receptor repertoire profiling
• 1040: Romi Van Doren (University of Antwerp) - Unraveling the complex TCR-microbiome interaction network in the colon
  
• 1100: break

Session 2: TCR applications

• 1120: Nicole La Gruta (Australia) - Revisiting the role of Lck-coreceptor association in TCR repertoire development and immune selection
  
• 1200: Eva Lion (Belgium) - Chasing T cells ex vivo, in vitro and in silico: TCR functionality, signature and engineering
  
• 1240: Grigorii Nos (Technical University of Denmark) - Exploring the phenotype and antigen specificity of engrafting CD8 T cell clones in patients undergoing adoptive cell therapy
• 1300: lunch

Session 3: TCR theory, data modeling & tools

• 1400: Phil Bradley (USA) - Leveraging deep neural networks for structure-based prediction of TCR:peptide-MHC interactions
  
• 1440: Aleksandra Walczak (France) - Convergence of immune repertoires
  
• 1520: Marius Messemaker (The Netherlands Cancer Institute) - STAPLER: Efficient learning of TCR-peptide specificity prediction from full-length TCR-peptide data
• 1540: break & poster session
  

Session 4: TCR applications

• 1600: Femke Van Wijk (The Netherlands) - Human T cells in time and space
  
• 1640: Benson Ogunjimi (Belgium) - TCRs matter in controlling viral reactivation
  
• 1720: Juan L. Melero (Omniscope) - Quantification of brain metastasis-infiltrating T cells in blood using ultra-deep single-cell T cell repertoire sequencing
• 1740: Hannah van Dijk (DKFZ Heidelberg) - Characterization of the human CD8 T cell response to vaccination with the malaria vaccine target Plasmodium falciparum circumsporozoite protein
  
• 1800: End of scientific session day 1
  

18:30-2200: Walking dinner (Horta, Antwerp)

Day 2

Session 5: TCR theory, data modeling & tools

• 0830: Registration
• 0900: Thierry Mora (France) - ​Response in immune repertoires
• 0940: Maria Martinez (Switzerland) - ​Interpretable deep learning for cancer personalized medicine
• 1020: Olga Lyudovyk (Cornell University) - Deep learning model to study T-cell mediated response to emerging COVID-19 strains
  
• 1040: break 
  

Session 6: TCR applications

• 1100: Diether Lambrechts (Belgium) - Single-cell characterisation of T-cell expansion during checkpoint immunotherapy
  
• 1140: Sabrina Pollastro (Sanquin Research) -  Monitoring birch pollen-specific CD4 T cell responses during immunomodulatory treatment
• 1200: Kerry Mullan (University of Antwerp) - STEGO.R for (easy) interrogation of combined scTCR repertoire and scRNA-seq data
  
• 1220: 10x Genomics sponsored talk: Barcode Enabled Antigen Mapping (BEAM): Multiplexed Antigen screening at single cell resolution
  
• 1225: lunch

Session 7: TCR theory, data modeling & tools

• 1330: Andreas Mayer (UK) - Measures of epitope binding degeneracy from T cell receptor repertoires 
• 1410: Morten Nielsen (Denmark) - Prediction of TCR-pMHC interactions: recent updates
  
• 1450: Giancarlo Croce (University of Lausanne) - Deep learning predictions of TCR specificity reveal functional chains in dual-alpha T cells
  
• 1510: break & poster session
  

Session 8: TCR applications

• 1530: Hedda Wardemann (Germany) - Functional TCR repertoire analysis after vaccination in humans
• 1610: Petra Bacher (Germany) - Modulation of human CD4+ T cell response by antigen specificity and cross-reactivity
  
• 1650: Koshlan Mayer-Blackwell (Fred Hutchinson Cancer Center) - Multimodal TCR sequencing design for characterizing T cell responses to mRNA vaccination in adults previously infected with SARS-CoV-2
  
• 1710: Alexandra Vujkovic (Institute for Tropical Medicine) - The diagnostic potential of activated CD8+ T cells during acute COVID-19
  
• 1730: meeting closure & end of ATCR23 by Pieter Meysman & Benson Ogunjimi

Last update: 2 May