- Multiprobe molecular imaging in the SAPAP3 KO mouse model for obsessive-compulsive disorder - Molecular Imaging Center Antwerp (MICA)
we want to exploit multimodal and multiprobe molecular imaging to investigate the neuropathophysiology of OCD in an animal model and to evaluate novel neuromodulation treatments which we miniaturized for use in rodents.
- Effects of repeated exposure to MK-801 and Ebselen evaluated by Magnetic Resonance Spectroscopy and Positron Emission Tomography in rat. - Molecular Imaging Center Antwerp (MICA)
Glutamate is the principal excitatory neurotransmitter in the brain and is at the base of a wide variety of neuropathologies, including epilepsy, autism, Fragile X, and obsessive compulsive disorder. Glutamate has also become the target for novel drugs in treatment and in fundamental research settings. However, much remains unknown on the working mechanisms of these drugs and the effects of chronic administration on the glutamatergic system. This study investigated the chronic effects of two glutamate-modulating drugs with imaging techniques to further clarify their working mechanisms for future research opportunities.
- Detection of spinal cord lesions in mice and treatment monitoring by MRI - Experimental Cell Transplantation Group, Laboratory for Experimental Hematology
- Multimodal whole-brain staging in tauopathy mouse models - Laboratory of Cell Biology & Histology, Veterinary Sciences
- Hindlimb suspension in rodents as model to study long-term effects of microgravity on the brain -
Antwerp University Research centre for Equilibrium and Aerospace (AUREA)
- The development of an off-the-shelf immunological combination therapy for glioblastoma multiforme Center for Oncology research (CORE)