Mission statement

The research theme ProSens (Processing of Sensory Information) aims at understanding the pathogenesis of neuromusculoskeletal disorders and chronic pain, and the underlying working mechanisms of rehabilitation interventions.

Focus Area

We focus on:

  • pathogenesis of neuromusculoskeletal disorders and chronic pain;
  • working mechanisms and mediating factors of rehabilitation interventions;
  • prognostic indicators for treatment outcome;

In the field of:

  • clinical neurology (e.g. rehabilitation of dizziness and balance disorders, stroke, tinnitus, headache disorders);
  • chronic pain management.


People’s daily functioning is often impaired by neuromusculoskeletal disorders and chronic pain.  Frequently, quality of life and ability to work are reduced in patients with conditions such as tinnitus or vertigo, as well as in patients with chronic pain (including neck pain, back pain, headache, dizziness, osteoarthritis, back pain and fibromyalgia). These disorders have a considerable individual, societal and economic impact.

Multiple intervention studies concerning physical therapy modalities have shown positive treatment effects in different patient populations. However, the treatment effect is often observed to be greatly heterogeneous, resulting in varying outcomes from responders, to non-responders and even adverse responders. Thus, to identify prognostic and mediating factors for treatment success or failure, and to improve the quality of these applied treatments, more insight is needed in the pathogenesis of the disorders to be treated, and in the underlying working mechanisms of the treatment interventions.

Place within MOVANT

This research theme adds to the expertise of MOVANT by focusing on the neurophysiological component. Close collaborations are ongoing with the research themes focusing on exercise physiology (Lifestyle Exchange), biomechanics (Motion) and quality of life (Improved Living).

By gaining more insight in neurophysiological mechanisms of both pathology and interventions, we can support the development and application of rehabilitation protocols within the other research themes. Inversely, we build on the expertise and rely on the input of other MOVANT members for building new research hypotheses and protocols.