Publications
Below is the full list of publications by Prof. Bert Maes. In many cases you have an option to access the full text of the publication at the journal web site and to download it as an Adobe PDF file by clicking on the Full Text link. Please note that in order to be able to download a paper, you or your institution must have a subscription for the corresponding journal. Alternatively, please feel free to contact us for a reprint of the paper.
2024
Selective C(aryl)–O bond cleavage in biorenewable phenolics
G. De Smet, X. Bai, B. U. W. Maes, Chem. Soc. Rev. 2024, in press
Advancements and Perspectives toward Lignin Valorization via O-Demethylation
X. Wu, E. Smet, F. Brandi, D. Raikwar, Z. Zhang, B. U. W. Maes, B. F. Sels, Angew. Chem. Int. Ed. 2024, e202317257.
Directed Palladium-Catalyzed γ-C(sp3)–H Alkenylation of (Aza and Oxa) Cyclohexanamines with Bromoalkenes: Bromide Precipitation as an Alternative to Silver Scavenging
K. Gadde, N. R. Bheemireddy, J. Heitkämper, A. Nova, B. U. W. Maes, ACS Catal. 2024, 14, 1157.
2023
Dearomative Spirocyclization of Tryptamine-Derived Isocyanides via Iron-Catalyzed Carbene Transfer
T. Roose, F. McSorley, B. Groenhuijzen, J. M. Saya, B. U. W. Maes, R. V. A. Orrù, E. Ruijter, J. Org. Chem. 2023, 88, 17345.
Synthesis of Levulinic Acids From Muconic Acids in Hot Water
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A Cobalt Mediated Nitrene Transfer aza-Wittig Cascade Reaction To Access 1,3,4-Oxadiazole Scaffolds
D.S. Verdoorn, P. Ranjan, T. de Reuver, E. Janssen, C.M.L. Vande Velde, J.M. Saya, B.U.W. Maes, R.V.A. Orru, Org. Lett., 2023, 25, 4005–4009.
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Direct Arylation of C(sp2)–H Bonds in Anilines
C. Jacob, J. Annibaletto, B.U.W. Maes, G. Evano, Synthesis, 2023, 55, 1799-1823.
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Iron-Catalysed Carbene Transfer to Isocyanides as a Platform for Heterocycle Synthesis
T. R. Roose, H. D. Preschel, H. M. Tejedor, J. C. Roozee, T. A. Hamlin, B. U. W. Maes, E. Ruijter, R. V. A. Orru, Chem. Eur. J., 2023, 29, e202203074.
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Emerging Activation Modes and Techniques in Visible-Light Photocatalyzed Organic Synthesis
D. De Vos, K. Gadde, B. U. W. Maes, Synthesis, 2023, 55, 193-231.
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Basic Concepts and Activation Modes in Visible-Light Photocatalyzed Organic Synthesis
K. Gadde, D. De Vos, B. U. W. Maes, Synthesis, 2023, 55, 164-192.
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Efficient Synthesis of Novel Plasticizers by Direct Palladium-catalyzed Di- or Multi-carbonylations
Y. Hu, R. Sang, R. Vroemans, G. Mollaert, R. Razzaq, H. Neumann, H. Junge, R. Franke, R. Jackstell, B. U.W. Maes, M. Beller, Angew. Chem. Int. Ed., 2023, e202214706.
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2022
A practical concept for catalytic carbonylations using carbon dioxide
R. Sang, Y. Hu, R. Razzaq, G. Mollaert, H. Atia, U. Bentrup, M. Sharif, H. Neumann, H. Junge, R. Jackstell, B. U.W. Maes, M. Beller, Nat. Commun., 2022, 13, 4432.
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Functional Regioregular (Poly)urethanes from Soft Nucleophilesand Cyclic Iminocarbonates
B. Grignard, P. Mampuys, J. Escudero, D. Masullo, F. Lemière, B. U.W. Maes, C. Detrembleur, Polymer Chemistry, 2022, 13, 6599-6605.
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Hydrogen borrowing: Towards aliphatic tertiary amines from lignin model compounds using a supported copper catalyst
D. Ruijten, T. Narmon, H. De Weer, R. van de Zweep, C. Poleunis, D. P. Debecker, B. U. W. Maes, B. F. Sels, ChemSusChem, 2022, 15, e202200868.
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Transition metal-catalysed carbene- and nitrene transfer to carbon monoxide and isocyanides
T. R. Roose, D. S. Verdoorn, P. Mampuys, E. Ruijter, B. U. W. Maes, R. V. A. Orru, Chem. Soc. Rev. 2022, 51, 5842-5877.
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Synthesis of Heterocycles via Aerobic Ni-Catalyzed Imidoylation of Aromatic 1,2-Bis-nucleophiles with Isocyanides
J. Escudero, P. Mampuys, C. Mensch, C. B. Bheeter, R. Vroemans, R. V. A. Orru, J. Harvey, B. U. W. Maes, ACS Catal. 2022, 12, 6857-6873.
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Selective Nickel-Catalyzed Hydrodeacetoxylation of Aryl Acetates
G. De Smet, X. Bai , C. Mensch, S.Sergeyev, G. Evano, B.U.W. Maes, Angew. Chem. Int. Ed. 2022, 61, e202201751. Hot Paper.
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Lignin-First Monomers to Catechol: Rational Cleavage of C-O and C-C Bonds over Zeolites
X. Wu, Y. Liao, J. Bomon, G. Tian, S.-T. Bai, K. Van Aelst, Q. Zhang, W. Vermandel, B. Wambacq, B.U.W. Maes, J. Yu, B. F. Sels, ChemSusChem 2022, 15, e202102248.
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2021
Expedient synthesis of bridged bicyclic nitrogen scaffolds via orthogonal tandem catalysis
S. Biswas, B. F. Van Steijvoort, M. Waeterschoot, N. Reddy Bheemireddy, G. Evano, B. U. W. Maes, Angew. Chem. Int. Ed. 2021, 60, 21988-21996. Hot Paper.
Highlighted in Synfacts 2021, 17, 1319
Featured in Org. Chem. Highlights: C-H Functionalization
1,3,7-Triazapyrene-Based ortho-Carborane Fluorophores: Convenient Synthesis, Theoretical Studies, and Aggregation-Induced Emission Properties
L. A. Smyshliaeva, M. V. Varaksin, E. I. Fomina, M. V. Medvedeva, T. S. Svalova, A. N. Kozitsina, O. P. Demidov, I. V. Borovlev, C. Mensch, P. Mampuys, B. U. W. Maes, V. N. Charushin, O. N. Chupakhin, Organometallics 2021, 40, 2792-2807.
Transient Directing Groups in Metal-Organic Cooperative Catalysis
B. U. W. Maes, G. Evano, C. Jacob, Chem. Eur. J. 2021, 27, 13899-13952.
3-Substituted 2-isocyanopyridines as versatile convertible isocyanides for peptidomimetic design
C. Hollanders, M. Elsocht, O. Van der Poorten, M. Jida, E. Renders, B.U.W. Maes, S. Ballet. Chem. Commun. 2021, 57, 6863-6866.
Homogeneous and heterogeneous catalysts for hydrogenation of CO2 to methanol under mild conditions
S. Bai, G. De Smet, Y. Liao, R. Sun, C. Zhou, M. Beller, B. U. W. Maes, B. F. Sels, Chem. Soc. Rev. 2021, 50, 4259-4298
Non-Directed Functionalization of Distal C(sp3)-H Bonds
B. U. W. Maes, C. Sambiagio, Remote C-H Bond Functionalizations: Methods and Strategies in Organic Synthesis, Chapter 12, 2021, 343-382
An efficient demethylation of aromatic methyl ethers with HCl in water
J. Bomon, M. Bal, T. K. Achar, S. Sergeyev, X. Wu, B. Wambacq, F. Lemiere, B. Sels, B. U. Maes, Green Chem. 2021, 23, 1995-2009
C(sp2)–H functionalization in non-aromatic azomethine-based heterocycles
A. A. Akulov, M. V. Varaksin, P. Mampuys, V. N. Charushin, O. N. Chupakhin, B. U. W. Maes, Org. Biomol. Chem. 2021, 19, 297-312
Access to Biorenewable and CO2-Based Polycarbonates from Exovinylene Cyclic Carbonates
F. Siragusa, E. Van Den Broeck, C. Ocando, A. J. Müller, G. De Smet, B. U. W. Maes, J. De Winter, V. Van Speybroeck, B. Grignard, C. Detrembleur, ACS Sustainable Chem. Eng. 2021, 9, 1714-1728.
HFIP-mediated 2-aza-Cope rearrangement: metal-free synthesis of α-substituted homoallylamines at ambient temperature
K. Gadde, B. U. W. Maes, K. Abbaspour Tehrani, Org. Biomol. Chem. 2021, 19, 4067-4075
Strecker-Derived Methodology for Library Synthesis of N-Acylated α‑Aminonitriles
P. Goncalves, A. Peeraer, Y. Adriaenssens, L. Zonnekien, P. Franck, B. U. W. Maes, K. Augustyns, P. Van Der Veken, ACS Omega 2021, 6, 1328-1338
2020
Thiosulfonylation of Unactivated Alkenes with Visible-Light Organic Photocatalysis
K. Gadde, P. Mampuys, A. Guidetti, H. V. Ching, W. A. Herrebout, S. Van Doorslaer, K. Abbaspour Tehrani, B. U. W. Maes, ACS Catal. 2020, 10, 8765-8779.
Synthesis of Densely Functionalized Pyrimidouracils by Nickel(II)-Catalyzed Isocyanide Insertion
J. W. Collet, B. Morel, H. Lin, T. R. Roose, P. Mampuys, R. V. A. Orru, E. Ruijter, B. U. W. Maes, Org. Lett. 2020, 22, 914-919.
Zn-Catalyzed Nicotinate-Directed Transamidations in Peptide Synthesis
K. Hollanders, E. Renders, C. Gadais, D. Masullo, L. Van Raemdonck, C. C. D. Wybon, C. Martin, W. A. Herrebout, B. U. W. Maes, S. Ballet, ACS Catal. 2020, 10, 4280-4289.
Highlighted in Synfacts 2020, 16, 0605
Brønsted Acid Catalyzed Tandem Defunctionalization of Biorenewable Ferulic acid and Derivates into Bio-catechol
J. Bomon, E. Van Den Broeck, M. Bal, Y. Liao, S. Sergeyev, V. Van Speybroeck, B. F. Sels, B. U. Maes, Angew. Chem. Int. Ed. 2020, 59, 3063-3068.
Base Metal-Catalyzed Isocyanide Insertions
J. W. Collet, T. R. Roose, E. Ruijter, B. U. Maes, R. Orru, Angew.Chem. Int. Ed. 2020, 59, 540-558.
Why we might be misusing Process Mass Intensity (PMI) and a methodology to apply it effectively as a discovery level metric
E. Monteith, P. Mampuys, L. Summerton, J. Clark, B. U. W. Maes, C. R. McElroy, Green Chem. 2020, 22, 123-135.
Palladium-Catalyzed Alkoxycarbonylation of sec-Benzylic Ethers
C. Schneider, R. Jackstell, B. U. W. Maes, M. Beller, Eur. J. Org. Chem. 2020, 2020, 932-936.
Synthesis – properties correlation and the unexpected role of the titania support on the Grignard surface modification
J. G. Van Dijck, P. Mampuys, H. V. Ching, D. Krishnan, K. Baert, T. Hauffman, J. Verbeeck, S. Van Doorslaer, B. U. Maes, M. Dorbec, A. Buekenhoudt, V. Meynen, Appl. Surf. Sci. 2020, 527, 146851.
The Non-innocent Role of Spin Traps in Monitoring Radical Formation in Copper-Catalyzed Reactions
M. Samanipour, H. Y. V. Ching, H. Sterckx, B. U. W. Maes, S. Van Doorslaer, Appl. Magn. Reson. 2020, 51, 1529-1542.
Synthesis of Quinazolin-4-ones by Copper-Catalyzed Isocyanide Insertion
J. W. Collet, E. A. van der Nol, T. R. Roose, B. U. W. Maes, R. V. A. Orru, J. Org. Chem. 2020, 85, 7378-7385.
2019
Directed C–H Functionalization Reactions with a Picolinamide Directing Group: Ni-Catalyzed Cleavage and Byproduct Recycling
S. Biswas, N. Bheemireddy, M. Bal, B. F. Van Steijvoort, B. U. W. Maes, J. Org. Chem.2019, 84, 13112-13123
Carbamate Synthesis Using a Shelf-Stable and Renewable C1 Reactant
Z. Dobi, B. N. Reddy, E. Renders, L. Van Raemdonck, C. Mensch, G. De Smet, C. Chen, C. Bheeter, S. Sergeyev, W. A. Herrebout, B. U. W. Maes, ChemSusChem2019, 12, 3103-3114
Lewis acidic FeCl3 promoted 2-aza-Cope rearrangement to afford α-substituted homoallylamines in dimethyl carbonate
K. Gadde, J. Daelemans, B. U. W. Maes, K. Abbaspour Tehrani, RSC Adv. 2019, 9, 18013-18017
Catalytic aerobic oxidation of C(sp3)-H bonds
H. Sterckx, B. Morel, B. U. Maes, Angewandte Chemie International Edition 2019, 58, 7946-7970
This review was highlighted in OPRD
A New Wave of Amide Bond Formations for Peptide Synthesis
K. Hollanders, B. U. W. Maes, S. Ballet, Synthesis 2019, 51, 2261-2277
Synthesis of Functionalized Pyrazin-2(1H)-ones via Tele-Nucleophilic Substitution of Hydrogen Involving Grignard Reactants and Electrophiles
P. Mampuys, T. D. Moseev, M. V. Varaksin, J. De Houwer, C. M. L. Vande Velde, O. N. Chupakhin, V. N. Charushin, B. U. W. Maes, Org. Lett. 2019, 21, 2699-2703
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This publication was highlighted in Synfacts.
Bio-based aromatic amines from lignin-derived monomers
E. Blondiaux, J. Bomon, M. Smolen, N. Kaval, F. Lemiere, S. Sergeyev, L. Diels, B. F. Sels, B. U. W. Maes, ACS Sustainable Chem. Eng. 2019, 7, 6906-6916
Ruthenium-Catalyzed Reductive Arylation of N-(2-Pyridinyl)amides with Isopropanol and Arylboronate Esters
T. O. Ronson, E. Renders, B. F. Van Steijvoort, X. Wang, C. C. D. Wybon, H. Prokopcová, L. Meerpoel, B. U. W. Maes, Angewandte Chemie International Edition 2019, 58, 482-487
This publication was highlighted in Synfacts.
2018
Synthesis of Pd complexes containing tailed NHC ligands and their use in a Semi-continuous membrane assisted Suzuki cross coupling process.
D. Ormerod, M. Dorbec, E. Merkul, N. Kaval, N. Lefèvre, S. Hostyn, L. Eykens, J. Lievens, S. Sergeyev, B. U. W. Maes, Org. Process Res. Dev. 2018, 22, 1509-1517
A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry
C. Sambiagio, D. Schönbauer, R. Blieck, T. Dao-Huy, G. Pototschnig, P. Schaaf, T. Wiesinger, M. F. Zia, J. Wencel-Delord, T. Besset, B. U. W. Maes, M. Schnürch, Chem. Soc. Rev. 2018, 47, 6603-6743
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Synthesis of Secondary Amides from Thiocarbamates
P. Mampuys, E. Ruijter, R. V. A. Orru, B. U. W. Maes Organic Letters 2018, 20, 4235-4239
This publication on ChemistryViews
Zn-catalyzed tert-butyl nicotinate-directed amide cleavage as a biomimic of metallo-exopeptidase activity
C. C. D. Wybon, C. Mensch, K. Hollanders, C. Gadais, W. A. Herrebout, S. Ballet, B. U. W. Maes ACS Catal., 2018, 8, 203–218
This paper was selected as the ACS Editors’ Choice
Chemical space screening around phe3 in opioid peptides: modulating µ versus δ agonism by suzuki-miyaura cross-couplings
T. Willemse, E. Eiselt, K. Hollanders, W. Schepens, H. W.T. van Vlijmen, N. N. Chung, V. Blais, B. Holleran, J.-M. Longpré, P. W. Schiller, B. U. W. Maes, P. Sarret, L. Gendron, S. Ballet, Bioorganic & Medicinal Chemistry Letters. 2018.
A bifunctional biased mu opioid agonist - neuropeptide FF receptor antagonist as analgesic with improved acute and chronic side effects
A. Drieu la Rochelle, K. Guillemyn, M. Dumitrascuta, C. Martin, V. Utard, R. Quillet, S. Schneider, F. Daubeuf, T. Willemse, P. Mampuys, B. U. W. Maes, N. Frossard, F. Bihel, M. Spetea, F. Simonin, S. Ballet, Pain 2018
Modular Three-Component Synthesis of 4-Aminoquinolines via an Imidoylative Sonogashira/Cyclization Cascade
J. W. Collet, K. Ackermans, J. Lambregts, B. U. W. Maes, R. V. A. Orru, Eelco Ruijter, J. Org. Chem. 2018, 83, 854-861
Rapid construction of substituted 3-amino-1,5-benzothiazepin-4(5H)-one dipeptide scaffolds through an Ugi-4CR – Ullmann cross-coupling sequence
O. Van der Poorten, R. Van Den Hauwe, K. Hollanders, B. U. W. Maes, D. Tourwé, M. Jidaa, S. Ballet, Org. Biomol. Chem. 2018, 16, 1242-1246
Zinc(II)-Catalyzed Synthesis of Propargylamines by Coupling Aldimines and Ketimines with Alkynes.
S. A. Shehzadi, A. Saeed, F. Lemière, B. U. W. Maes, K. Abbaspour Tehrani, Eur. J. Org. Chem. 2018, 78–88
2017
Proton Sponge Analogue of the Tröger's Base: A Compound with Remarkable Enantiomeric Stability
V. A. Ozeryanskii, M. P. Vlasenko, A. F. Pozharskii, S. Sergeyev, B. U. W. Maes, P. Franck, W. A. Herrebout, ChemistrySelect 2017, 2, 9882-9887
Copper-Catalyzed Aerobic Oxygenation of Benzylpyridine N-Oxides and Subsequent Post-Functionalization
H. Sterckx, C. Sambiagio, V. Médran-Navarrete, B. U. W. Maes, Adv. Synth. Catal.2017, 359, 3226-3236
Combining Isocyanides with Carbon Dioxide in Palladium-Catalyzed Heterocycle Synthesis: N3-Substituted Quinazoline-2,4(1H,3H)-diones via a Three-Component Reaction
P. Mampuys, H. Neumann, S. Sergeyev, R. V. A. Orru, H. Jiao, A. Spannenberg, B. U. W. Maes, M. Beller, ACS Catalysis2017, 7, 5549-5556
Electrosynthesis: A New Frontier in Aerobic Oxidation?
C. Sambiagio, H. Sterckx, B. U. W. Maes, ACS Central Science2017, 3, 686-688
Amine Activation: N-Arylamino Acid Amide Synthesis from Isothioureas and Amino Acids
Y.‐P. Zhu, P. Mampuys, S. Sergeyev, S. Ballet, B. U. W. Maes, Adv. Synth. Catal. 2017, 359, 2481-2498
Carbon–Nitrogen Bond Formation Through Cross-Dehydrogenative Coupling Reactions
M. Baeten, B. U. W. Maes, Advances in Organometallic Chemistry2017, 67, 401-481
Iron-Catalyzed Aerobic Oxidation of (Alkyl)(aryl)azinylmethanes
H. Sterckx, C. Sambiagio, F. Lemière, K. A. Tehrani, B. U. W. Maes, Synlett2017, 28, 1564-1569
Published as part of the Cluster Catalytic Aerobic Oxidations (cluster editors: Shannon S. Stahl and Tomislav Rovis).
The Suzuki–Miyaura Cross-Coupling as a Versatile Tool for Peptide Diversification and Cyclization.
T. Willemse, W. Schepens, H. W. T. van Vlijmen, B. U. W. Maes, S. Ballet, Catalysts2017, 7, 74
This article belongs to the Special Issue Suzuki–Miyaura Cross-Coupling Reaction and Potential Applications.
Cooperative Electrocatalytic and Chemoselective Alcohol Oxidation by Shvo's Catalyst.
J. Lybaert, S. Trashin, B. U. W. Maes, K. De Wael, K. A. Tehrani, Adv. Synth. Catal.2017, 359, 919–925
“Dark” Singlet Oxygen and EPR Spin Trapping as Convenient Tools to Assess Photolytic Drug Degradation.
P. Persich, S. Hostyn, C. Joie, G. Winderickx, J. Pikkemaat, E. P. Romijn, B. U. W. Maes, Journal of Pharmaceutical Sciences2017, 106, 1310-1316
Concise Xanthine Synthesis via a Double Amidination Reaction of a 6-Chlorouracil with Amidines using Base Metal Catalysis.
B. Morel, P. Franck, J. Bidange, S. Sergeyev, D. Smith, J. Moseley, B. U. W. Maes, ChemSusChem. 2017, 10, 624-628
An Evaluation of Credentials of a Multicomponent Reaction for the Synthesis of Isothioureas Through the Use of the Holistic CHEM21 Green Metrics Toolkit.
S. Abou-Shehada, P. Mampuys, B. U. W. Maes, J. Clark, L. Summerton, Green Chem.2017, 19, 249-258
2016
Amine Activation: Synthesis of N‐(Hetero)arylamides from Isothioureas and Carboxylic Acids.
Y.-P. Zhu, S. Sergeyev, P. Franck, R. V. A. Orru, B. U. W. Maes, Org. Lett.2016, 18, 4602–4605.
Remote Functionalization: Palladium-Catalyzed C5(sp3)-H Arylation of 1-Boc-3-aminopiperidine Through the Use of a Bidentate Directing Group.
B. F. Van Steijvoort, N. Kaval, A. A. Kulago, B. U. W. Maes, ACS Catalysis2016, 6, 4486–4490.
A Journey Through Metal-Catalyzed C-H Functionalization of Heterocycles: Insights and Trends.
J. Maes, B. U. W. Maes, Advances in Heterocyclic Chemistry2016, 120, 137–194
Iodide-Catalyzed Synthesis of Secondary Thiocarbamates from Isocyanides and Thiosulfonates.
P. Mampuys, Y. Zhu, S. Sergeyev, E. Ruijter, R. V. A. Orru, S. Van Doorslaer, B. U. W. Maes, Org. Lett. 2016, 18, 2808-2811.
Palladium-Catalyzed Construction of Amidines from Arylboronic Acids under Oxidative Conditions.
F. Zhu, Y. Li, Z. Wang, R. Orru, B. Maes, X.-F. Wu, Chem. Eur. J.2016, 22, 7743 – 7746.
On the potential of homogeneous Pd catalyst separation by ceramic membranes. Application to down-stream and continuous flow processes.
D. Ormerod, N. Lefevre, M. Dorbec, I. Eyskens, P. Vloemans, K. Duyssens, V. Diez de la Torre, N. Kaval, E. Merkul, S. Sergeyev, B. U. W. Maes, Org. Process Res. Dev. 2016, 20, 911-920.
Base Metals in Catalysis: From Zero to Hero.
J. Maes, E. A. Mitchell, B. U. W. Maes, in Green and Sustainable Medicinal Chemistry: Methods, Tools and Strategies for the 21st Century Pharmaceutical Industry, 2016, 192-202.
2,6-Di(Arylamino)-3-Fluoropyridine Derivatives as HIV Non-Nucleoside Reverse Transcriptase Inhibitors
S. Sergeyev, A. K. Yadav, P. Franck, J. Michiels, P. Lewi, J. Heeres, G. Vanham,K. K. Ariën, C. M. L. Vande Velde, H. De Winter, B. U. W. Maes, J. Med. Chem.2016, 59, 1854–1868.
Base metal-catalyzed benzylic oxidation of (aryl)(heteroaryl)methanes with molecular oxygen.
H. Sterckx, J. De Houwer, C. Mensch, W. A. Herrebout, K. Abbaspour Tehrani, B. Maes, Beilstein J. Org. Chem.2016, 12, 144–153.
Guanidine Synthesis: Use of Amidines as Guanylating Agents.
M. Baeten, B. U. W. Maes, Adv. Synth. Catal.2016, 358, 826–833.
Mechanism of the CuII-Catalyzed Benzylic Oxygenation of (Aryl)(heteroaryl)methanes with Oxygen.
H. Sterckx, J. De Houwer, C. Mensch, I. Caretti, K. Abbaspour Tehrani, W. A. Herrebout, S. Van Doorslaer, B. Maes, Chem. Sci.2016, 7, 346-357.
2015
On the Triple Role of Fluoride Ions in Palladium-Catalyzed Stille Reactions.
M. Hervè, G. Lefèvre, E. A. Mitchell, B. U. W. Maes, A. Jutand, Chem. Eur. J. 2015, 21, 18401–18406.
Selected as Hot Article.
The electrochemistry of tetrapropylammonium perruthenate, its role in the oxidation of primary alcohols and its potential for electrochemical recycling.
J. Lybaert, B.U.W. Maes, K. Abbaspour Tehrani, K. De Wael, Electrochimica Acta2015, 182, 693-698.
Suzuki–Miyaura Diversification of Amino Acids and Dipeptides in Aqueous Media.
T. Willemse, K. Van Imp, R. J. M. Goss, H. W. T. Van Vlijmen, W. Schepens, B. U. W. Maes, S. Ballet, ChemCatChem 2015, 7, 2055-2070.
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Oxidative Addition of Haloheteroarenes to Palladium(0): Concerted versus SNAr-Type Mechanism.
B. U. W. Maes, S. Verbeeck, T. Verhelst, A. Ekomié, N. von Wolff, G. Lefèvre, E. A. Mitchell, A. Jutand, Chem. Eur. J.2015, 21, 7858–7865.
Synthesis of Secondary Amides from N-Substituted Amidines by Tandem Oxidative Rearrangement and Isocyanate Elimination.
P. Debnath, M. Baeten, N. Lefèvre, S. Van Daele, B. U. W. Maes, Adv. Synth. Catal.2015, 357, 197-209.
2014
Sustainable Three-Component Synthesis of Isothioureas from Isocyanides, Thiosulfonates, and Amines.
P. Mampuys, Y.-P. Zhu, T. Vlaar, E. Ruijter, R. V. A. Orru, B. U. W. Maes, Angew. Chem. Int. Ed. 2014, 53, 13063-13068.
Synthesis of Aryl(di)azinylmethanes and Bis(di)azinylmethanes via Transition-Metal-Catalyzed Cross-Coupling Reactions.
J. De Houwer, B. U. W. Maes, Synthesis 2014, 46, 2533-2550.
The First One-Pot Synthesis of l-7-Iodotryptophan from 7-Iodoindole and Serine, and an Improved Synthesis of Other l-7-Halotryptophans.
D. R. M. Smith, T. Willemse, D. S. Gkotsi, W. Schepens, B. U. W. Maes, S. Ballet, R. J. M. Goss. Org. Lett. 2014, 16, 2622-2625.
Directed Ruthenium-Catalyzed C(sp3-H α-Alkylation of Cyclic Amines Using Dioxolane-Protected Alkenones.
A. Kulago, B. Van Steijvoort, E. Mitchell, L. Meerpoel, B. U. W. Maes. Adv. Synth. Catal. 2014, 356, 1610-1618.
Catalyst-free microwave-assisted conversion of free fatty acids in triglyceride feedstocks with high acid content.
J. Geuens, S. Sergeyev, B. U. W. Maes, S. Tavernier. Renewable Energy 2014, 68, 524–528.
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Synthesis of Diverse Azolo[c]quinazolines by Palladium(II)- Catalyzed Aerobic Oxidative Insertion of Isocyanides.
Vlaar, T.; Bensch, L.; Kraakman, J.; Vande Velde, C.M.L.; Maes, B.U.W.; Orru, R.V.A.; Ruijter, E. Adv. Synth. Catal. 2014, 356, 1205-1209.
Synthesis of Pyridopyrimidines by Palladium-Catalyzed Isocyanide Insertion.
Estevez, V.; Van Baelen, G.; Lentferink, B.H.; Vlaar, T.; Janssen, E.; Maes, B.U.W.*; Orru, R.V.A.*; Ruijter, E.* ACS Catalysis 2014, 4, 40–43.
Antiprotozoal Activity of Synthetic Amino Substituted 1-Methyl-1H-alpha-carbolines.
Verbeeck, S.; Yadav, A.K.; Maes, B.U.W.; Augustyns, K.; Van der Veken, P.; Cos, P.; Maes, L.; Pieters, L.* Pharmazie 2014, 69, 83–85.
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2013
Palladium-Catalyzed Synthesis of 2-Aminobenzoxazinones by Aerobic Oxidative Coupling of Anthranilic Acids and Isocyanides.
Vlaar, T.; Orru, R.V.A.*; Maes, B.U.W.*; Ruijter, E.* J. Org. Chem. 2013, 78, 10469–10475.
Removal of the Pyridine Directing Group from alpha-Substituted N-(pyridin-2-yl)piperidines obtained via Directed Ru-catalyzed sp3 C-H Functionalization.
Smout, V.; Peschiulli, A.; Verbeeck, S.; Herrebout, W.; Bultinck, P.; Vande Velde, C.M.L.; Berthelot, D.; Meerpoel, L.; Maes, B.U.W.* J. Org. Chem. 2013, 78, 9803–9814.
Synthesis of 4-Aminoquinolines by Aerobic Oxidative Palladium-Catalyzed Double C–H Activation and Isocyanide Insertion.
Vlaar, T.; Maes, B.U.W.; Ruijter, E.*; Orru, R.V.A.* Chem. Heterocycl. Compd. (Khimiya Geterotsiklicheskikh Soedinenii) 2013, 966-972.
A new method to graft titania using Grignard reagents.
P. Van Heetvelde, E. Beyers, K. Wyns, P. Adriaensens, B Maes, S. Mullens, A. Buekenhoudt, V. Meynen. Chem. Commun. 2013, 49, 6998-7000.
Palladium-catalyzed migratory insertion of isocyanides: an emerging platform in cross-coupling chemistry.
T. Vlaar, B. Maes, E. Ruijter, R. V. A. Orru. Angew. Chem. Int. Ed. 2013, 52, 7084-7097.
Ruthenium catalyzed alpha-(hetero)arylation of saturated cyclic amines: reaction scope and mechanism.
A. Peschiulli, V. Smout, T. E. Storr, E. Mitchell, Z. Eliáš, W. Herrebout, D. Berthelot, L. Meerpoel, B. Maes. Chem. Eur. J. 2013, 10378-10387.
Multicomponent Synthesis of 4-Aminophthalazin-1(2H)-ones by Palladium-Catalyzed Isocyanide Insertion.
T. Vlaar, P. Mampuys, M. Helliwell, B. U. W. Maes, R. V. A. Orru, E. Ruijter, E. J. Org. Chem. 2013, 78, 6735-6745.
Research highlighted in Synfacts2013, 9, 1055.
Synthesis of C8-N9 annulated purines via iron catalyzed C-H amination.
J. Maes, T. Rauws, B. Maes. Chem. Eur. J. 2013, 19, 9137–9141.
Influence of the Free Fatty Acids, Water, Temperature, and Reaction Time on the Catalyst-Free Microwave-Assisted Transesterification of Triglycerides with 1-Butanol.
J. Geuens, S. Sergeyev, B. U. W. Maes, S. Tavernier. Energy Fuels 2013, 27, 2637-2642.
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"Base Effect" in the Auto-Tandem Palladium-Catalyzed Synthesis of Amino-Substituted 1-Methyl-1H-α-carbolines.
A. K. Yadav, S. Verbeeck, S. Hostyn, P. Franck, S. Sergeyev, B. U. W. Maes*. Org. Lett. 2013, 15, 1060-1063.
2012
Sustainable Synthesis of Diverse Privileged Heterocycles by Palladium-Catalyzed Aerobic Oxidative Isocyanide Insertion.
T. Vlaar, R. C. Cioc, P. Mampuys, B. U. W. Maes,* R. V. A. Orru,* E. Ruijter. Angew. Chem. Int. Ed. 2012, 51, 13058-13061.
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An indium(III)-catalyzed synthesis of 4,4-dichloro-1-aryl-N-alkyl-1-yn-3-amines via an intermolecular C(sp2)-C(sp) bond formation.
C. Malakar, B. U. W. Maes, K. A. Tehrani. Adv. Synth. Catal. 2012, 354, 3461-3467.
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Aptamer-Based Molecular Recognition of Lysergamine, Metergoline and Small Ergot Alkaloids.
E. Rouah-Martin, J. Mehta, B. van Dorst, S. de Saeger, P. Dubruel, B.U.W. Maes, F. Lemiere, E. Goormaghtigh, D. Daems, W. Herrebout, F. van Hove, R. Blust, J. Robbens. Int. J. Mol. Sci. 2012, 13, 17138-17159.
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Is their potential for post-synthetic brominating reactions on benzene bridged PMOs?
G. Smeulders, V. Meynen, K. Houthoofd, S. Mullens, J. A. Martens, B. U. W. Maes, P. Cool. Microporous and Mesoporous Materials 2012, 164, 49-55.
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The Role of the Alcohol and Carboxylic Acid in Directed Ruthenium-Catalyzed C(sp3)-H α-Alkylation of Cyclic Amines.
S. D. Bergman, T. E. Storr, H. Prokopcova, K. Aelvoet, G. Diels, L. Meerpoel, B. U. W. Maes. Chem. Eur. J. 2012, 18, 10393-10398.
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Direct α-Functionalization of Saturated Cyclic Amines.
E. A. Mitchell, A. Peschiulli, N. Lefevre, L. Meerpoel, B. U. W. Maes. Chem. Eur. J. 2012, 18, 10092-10142.
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Synthesis of Aryl(di)azinyl Ketones through Copper- and Iron-catalyzed Oxidation of the Methylene Group of Aryl(di)azinylmethanes.
J. De Houwer, K. A. Tehrani, B. U. W. Maes. Angew. Chem. Int. Ed. 2012, 51, 2745–2748. Highlighted in Synfacts 2012, 8, 0590.
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Transition metal-catalyzed N-arylations of amidines and guanidines.
T. R. M. Rauws, B. U. W. Maes. Chem. Soc. Rev. 2012, 41, 2463-2497.
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Selection and Characterization of PCB-Binding DNA Aptamers.
J. Mehta, E. Rouah-Martin, B. Van Dorst, B. Maes, W. Herrebout, M.-L. Scippo, F. Dardenne, R. Blust, J. Robbens. Anal. Chem. 2012, 84, 1669–1676.
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2011
Synthesis of 4-Aminoquinazolines by Palladium-Catalyzed Intramolecular Imidoylation of N-(2-Bromoaryl)amidines.
G. Van Baelen, S. Kuijer, L. Rýček, S. Sergeyev, E. Janssen, F. J. J. de Kanter, B. U. W. Maes, E. Ruijter, R. V. A. Orru. Chem. Eur. J. 2011, 15039-15044.
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Synthesis of (Hetero)arylated Pyridazin-3(2H)-ones via Negishi reaction involving Zincated Pyridazin-3(2H)-ones.
T. Verhelst, Z. Liu, J. Maes, B. U. W. Maes*. J. Org. Chem. 2011, 76, 9648–9659.
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Palladium-Catalyzed Synthesis of 4-Aminophthalazin-1(2H)-ones by Isocyanide Insertion.
T. Vlaar, E. Ruijter*, A. Znabet, E. Janssen, F. J. J. de Kanter, B. U. W. Maes, R. V. A. Orru. Org. Lett. 2011, 6496-6499.
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Smart heating profiles for the synthesis of benzene bridged periodic mesoporous organosilicas.
G. Smeulders, C. J. Van Oers, K. Van Havenbergh, K. Houthoofd, M. Mertens, J. A. Martens, S. Bals, Bert U.W. Maes, V. Meynen, P. Cool. Chemical Engineering Journal 2011, 175, 585-591.
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Oxidative aryl amination of 1,3-dinitrobenzene and 3-nitropyridine under anaerobic conditions: the dual role of the nitroarenes.
A. V. Gulevskaya, I. N. Tyaglivaya, S. Verbeeck, B. U. W. Maes, A. V. Tkachuk. ARKIVOC 2011, 9, 238-251.
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Synthesis of Functionalized Pyridazin-3(2H)-ones via Selective Bromine–Magnesium Exchange and Lactam Directed Ortho C–H Magnesiation.
T. Verhelst, J. Maes, Z. Liu, S. Sergeyev, B. U. W. Maes*. J. Org. Chem. 2011, 76, 6670–6677.
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On the Importance of Acid Additive in the Synthesis of Pyrido[1,2-a] benzimidazoles through Directed Copper-Catalyzed Amination.
K. S. Masters, T. R. M. Rauws, A. K. Yadav, W. A. Herrebout, B. Van der Veken, B. U. W. Maes*. Chem. Eur. J. 2011, 17, 6315-6320.
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Synthesis of 3-substituted benzo[g]isoquinoline-5,10-diones: a convenient one-pot Sonogashira coupling/iminoannulation procedure.
S. Van Aeken, S. Verbeeck, J. Deblander, B. U. W. Maes, K. A. Tehrani*. Tetrahedron 2011, 67, 2269-2278.
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Highly efficient one-pot synthesis of D-ring chloro-substituted neocryptolepines via a condensation—Pd-catalyzed intramolecular direct arylation strategy.
S. Hostyn, K. A. Tehrani, F. Lemière, V. Smout, B. U. W. Maes*. Tetrahedron 2011, 67, 655-659.
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Synthesis of Functionalized Pyridazin-3(2H)-ones via Nucleophilic Substitution of Hydrogen (SNH).
T. Verhelst, S. Verbeeck, O. Ryabtsova, S. Depraetere, B. U. W. Maes*. Org. Lett. 2011, 13, 272-275.
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2010
C-2 Arylation of Piperidines via Directed Transition Metal-Catalyzed sp3 C-H Activation.
H. Prokopcova, S. D. Bergman, K. Aelvoet, V. Smout, W. A. Herrebout, B. J. van der Veken, L. Meerpoel, B. U. W. Maes*. Chem. Eur. J. 2010, 16, 13063-13067.
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Dual Effect of Halides in the Stille Reaction: in-situ Halide Metathesis and Catalyst Stabilization.
S. Verbeeck, C. Meyers, P. Franck, A. Jutand, B. U. W. Maes*. Chem. Eur. J. 2010, 16, 12831-12837.
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A DFT Study of Site-Selectivity in Oxidative Addition Reactions with Pd0 Complexes: The Effect of an Azine Nitrogen and the Use of Different Types of Halogen Atoms in the Substrate.
W. A. Herrebout, N. Nagels, S. Verbeeck, B. J. van der Veken, B. U. W. Maes*. Eur. J. Org. Chem. 2010, 3152-3158.
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ONSH: Optimization of Oxidative Alkylamination Reactions through Study of the Reaction Mechanism.
S. Verbeeck, W. A. Herrebout, A. V. Gulevskaya, B. J. van der Veken, B. U. W. Maes*. J. Org. Chem. 2010, 75, 5126-5133.
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Synthesis of new tetracyclic azaheteroaromatic cores via auto-tandem Pd-catalyzed and one-pot Pd- and Cu-catalyzed double C-N bond formation.
T. Rauws, C. Biancalani, J. W. De Schutter, B. U. W. Maes*. Tetrahedron 2010, 66, 6958-6964.
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2009
Synthesis of Functionalized Pyridazin-3(2H)-ones via Bromine-Magnesium Exchange on Bromopyridazin-3(2H)-ones.
O. Ryabtsova, T. Verhelst, M. Baeten, C. M. L. Vande Velde, B. U. W. Maes*. J. Org. Chem. 2009, 74, 9440-9445.
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Structure - Activity Relationship of Antiparasitic and Cytotoxic Indoloquinoline Alkaloids, and their Tricyclic and Bicyclic Analogues.
G. Van Baelen, S. Hostyn, L. Dhooghe, P. Tapolcsányi, P. Mátyus, G. Lemière, R. Dommisse, M. Kaiser, R. Brun, P. Cos, L. Maes, G. Hajós, Z. Riedl, I. Nagy, B.U.W. Maes, L. Pieters* , Bioorg. Med. Chem. 2009, 17, 7209-7217.
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Synthesis and Antiplasmodial Activity of Alkylamino-Substituted Neocryptolepine Derivatives.
I. el Sayed, P. van der Veken, K. Steert, L. D’Hooghe, S. Hostyn , G. Van Baelen, G. Lemière, B.U.W. Maes, P. Cos, L. Maes, J. Joossens, A. Haemers, L. Pieters, K. Augustyns*, J. Med. Chem. 2009, 52, 2979-2988.
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Synthesis of N-Alkyl-nitroareneamines via Oxidative Alkylamination of Nitroarenes.
A.V. Gulevskaya*, S. Verbeeck, O.N. Burov, C. Meyers, I.N. Korbukova, W. Herrebout, B.U.W. Maes*, Eur. J. Org. Chem. 2009, 564-574.
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Synthesis of 5-methyl-5H-pyrrolo[2,3-c]quinoline and 4-methyl-4H-pyrrolo[2,3-c]isoquinoline: two new unnatural D-ring stripped isomers of the cryptolepine series.
G. Van Baelen, G.L.F. Lemière, R.A. Dommisse, B.U.W. Maes*, Arkivoc 2009, 174-182.
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The CH...π Interaction in the Halothane/Ethene Complex: a Cryosolution Infrared and Raman Study.
J.J.J. Dom, B. Michielsen, B.U.W. Maes, W.A. Herrebout, B.J. van der Veken*, Chem. Phys. Lett. 2009, 469, 85-89.
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Rapid Microwave-Assisted synthesis of Benzene Bridged Periodic Mesoporous Organosilicas.
G.Smeulders*, V. Meynen, G. Van Baelen, M. Mertens, O.I. Lebedev, G. Van Tendeloo, B.U.W. Maes, P. Cool, J. Mater. Chem. 2009, 19, 3042-3048.
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