Examples of biomedical research

Animal models of human diseases

Non invasive in vivo neuro imaging for phenotyping (transgenic) mouse or rat models for human neurological diseases outside our main research topics

Ventricles and cerebellum
Figure 1 : 3D reconstruction of the ventricles (red) and cerebellum (purple) from in vivo MRI-data demonstrating anatomical abnormalities of the central nervous system of a transgenic mouse model for Williams Syndrome (left) with respect to a control mouse (right).

 

Mice sacroiliac joints
Figure 2 : MRI imaging of mice sacroiliac joints was found to be an important tool to monitor axial inflammation in as preclinical models of spondyloarthropathy.