Cytotoxic chemotherapy is a commonly used treatment for curing breast cancer, prostate cancer and lung cancer. Cytotoxic chemotherapy may however also induce serious side effects such as nail changes (e.g., color, brittleness, damages, ...). In its most severe form, this may lead to onycholysis or the releasing of a portion of the nail, which is often preceded or accompanied by severe pain. Nail toxicity is observed at 44% of patients treated with taxanes. Nail toxicity can be avoided or mitigated through the use of ice gloves. Ice gloves are cooled to -20 ° C and worn during a chemotherapeutic treatment. Unfortunately, the use of ice gloves is very painful and therapeutic compliances are limited.
This project allows to develop a medical instrument to avoid nail toxicity at cancer patients. The instrument aims to allow a painless and effective prevention of nail toxicity.