Organic chemistry I

Course Code :1001WETORC
Study domain:Chemistry
Academic year:2017-2018
Semester:2nd semester
Contact hours:50
Credits:5
Study load (hours):140
Contract restrictions: Exam contract not possible
Language of instruction:Dutch
Exam period:exam in the 2nd semester
Lecturer(s)Kourosch Abbaspour Tehrani
Veerle Smout

3. Course contents *

In this introductory course in organic chemistry, the different classes of organic compounds and their functional groups (nomenclature included) will be treated systematically. Important basic concepts such as isomers, rotamers, conformers, tautomers, resonance and aromaticity will be explained using examples and exercises. The basis will also be laid for the concept reactivity by introducing the terms "nucleophile" and "electrophile" and the use of various kinetic and thermodynamic laws. After this thorough introduction follows the discussion of the various reactivity classes and their applications in the synthesis: olefins and alkynes (electrophilic addition), halogenoalkanes (nucleophilic substitution and elimination), alcohols, organometals, epoxides, ethers, and sulfur analogs of alcohols. Because of the importance of organic molecules in our society will be given several illustrations from the pharmaceutical and agrochemical industries. Given the importance of biomolecules in biochemistry the similarity will be demonstrated between biochemical reactions and organic chemical reactions. In the context of the growing importance of sustainability examples in the area of green chemistry will be provided.