In this introductory course in organic chemistry, the different classes of organic compounds and their functional groups (nomenclature included) will be treated systematically.
Important basic concepts such as isomers, rotamers, conformers, tautomers, resonance and aromaticity will be explained using examples and exercises. The basis will also be laid for the concept reactivity by introducing the terms "nucleophile" and "electrophile" and the use of various kinetic and thermodynamic laws.
After this thorough introduction follows the discussion of the various reactivity classes and their applications in the synthesis: olefins and alkynes (electrophilic addition), alkyl halides (nucleophilic substitution and elimination), alcohols, organometals, epoxides, ethers, and sulfur analogs of alcohols.
Because of the importance of organic molecules in our society, several illustrations will be given from the pharmaceutical and agrochemical industry. Given the importance of biomolecules in biochemistry the similarity will be demonstrated between biochemical reactions and organic chemical reactions. In the context of the growing importance of sustainability examples in the area of green chemistry will be provided.