Biochemical engineerstechniques

Course Code :1002WETBIR
Study domain:Engineering Sciences
Academic year:2019-2020
Semester:2nd semester
Contact hours:40
Study load (hours):112
Contract restrictions: Exam contract not possible
Language of instruction:Dutch
Exam period:exam in the 2nd semester
Lecturer(s)Ronnie Willaert
Tom Tytgat
Birgit Uytterhoeven

3. Course contents *

The course is divided into four chapters. In the introductory chapter, the field "Biochemical Engineering" is explained. Stoichiometry and kinetics of bioprocesses is explained in the second chapter. The emphasis is on preparing stoichiometric equations for microbial reactions, and homogeneous and heterogeneous reaction kinetics for both enzymes and cells as biocatalysts. Chapter three deals with  "bioreactor engineering". The various bioreactor configurations and their design are discussed. Next, the ideal operation of the bioreactor (especially the batch, fed batch, the continuous stirred tank and the plug flow reactor) are treated. The final section focuses on physical and thermal transport phenomena in bioreactors. How to set up energy balances for cellular bioprocesses in bioreactors is discussed. Finally, mass transfer in bioreactors and scaling up of bioreactors is discussed.


The topics that will be discussed are: 

  • 1 Introduction: biotechnology and biochemical engineering 1.1 Biotechnology 1.2 Biochemical engineering 1.3 Bioprocesses versus chemical processes 1.4 Books and journals 
  • 2 Stoichiometry and kinetics of bioprocesses 2.1 Stoichiometry of microbial reactions 2.2 Homogeneous reaction kinetics 2.3 Heterogeneous reaction kinetics 
  • 3 Biorector engineering 3.1 Bioreactor configurations and design 3.2 The operation of an ideal bioreactor 
  • 4 Physical and thermal transport phenomena in bioreactors 4.1 Energy balances for cellular processes in bioreactors 4.2 Mass transfer in bioreactors 4.3 Up scaling of bioreactors