Supramolecular chemistry

Course Code :2001WETSMC
Study domain:Chemistry
Bi-anuall course:Taught in academic years starting in an odd year
Academic year:2019-2020
Semester:2nd semester
Contact hours:25
Credits:3
Study load (hours):84
Contract restrictions: No contract restriction
Language of instruction:English
Exam period:exam in the 2nd semester
Lecturer(s)Wim Dehaen

3. Course contents *

In this course a solid introduction to supramolecular chemistry is given.  Some introductory concepts (non-covalent interactions, self-processes) are treated extensively.  In the first part synthesis and properties of ion-receptors are treated (crown-ethers and the like), and their applications in synthetic and analytical chemistry.  The principles that determine the formation of macro-rings (effective molarity, template effect, high-dilution principle, cesium effect) are given.  Apart from kation receptors the molecular recognition of neutral molecules and anions is shortly treated.  In the second part synthesis and properties of cyclofanes are treated.  Such concepts as hydrophobic effect and the linear free energy ratio are explained.  Different types of cyclofanes, among which calyx(n)arenes, resorcinarenes, cycloveratrylenes and calixoyrroles are treated.  In the last part of the course some remarkable recent examples from the literature on supramolecular chemistry are treated.