Metrics: Exposure and Outcome Assessment

Course Code :2050GENEP1
Study domain:Epidemiology
Academic year:2019-2020
Semester:2nd semester
Contact hours:21
Study load (hours):84
Contract restrictions: Faculty decision based on student file
Language of instruction:English
Exam period:exam in the 2nd semester
Lecturer(s)Annelies Van Rie
Guido Van Hal
Jarl Kampen

3. Course contents *

Epidemiological research uses various exposure, outcome and covariate metrics. The choice of a specific metric will depend on the study in question, the resources available, and biologic considerations. This course surveys the major issues relevant to the measurement of exposures and outcomes in epidemiological research. Through the communication of theoretical concepts and the discussion of examples and case studies, students will gain understanding in the best practices of (1) questionnaire development, (2) application of biomarkers in epidemiological research, including the logistical hurdles in biospecimen collection and storage, assessments of biomarker quality, (3) measurement of environmental exposures, (4) use of surrogate endpoints, (5) how to use a DAG to select covariates to be measured for an exposure-outcome association, (5) how to avoid bias in exposure and outcome measurement and (6) how to avoid misclassification bias.