Programme | Antwerp TCR conference 2025

Schedule

Morning Session:

08:30 - 09:00:
Registration and coffee
09:00 - 09:10:
Opening and welcome
09:10 - 09:55:
Interindividual TCR repertoire diversity of epitope-specific CD8+ T cell populations
Dirk Busch (Technical University of Munich)
09:55 - 10:40:
Broadening the range of therapeutic targets using T-cell receptors
Johanna Olweus (Oslo University Hospital)
10:40 - 10:45:
Seqalis sponsored talk
10:45 - 11:15:
Coffee Break
11:15 - 12:00:
TCR cross-reactivity and generalisation during T cell tolerance induction
Hannah Meyer (Cold Spring Harbor Laboratory)
12:00 - 12:45:
Differentiation and maintenance of exhausted CD4 and CD8 T cells
Dietmar Zehn (Technical University of Munich)
12:45 - 13:45:
Lunch Break

Afternoon Session:

13:45 - 14:30:
T cell receptor driven fate of antigen-specific T cells in vivo
Kilian Schober (Uniklinikum Erlangen)
14:30 - 15:30: Short Talks
- Revealing the hidden sequence distribution of epitope-specific TCR repertoires and its influence on machine learning model performance (Sofie Gielis)
- Fine-scale Mapping of TCR-antigen Interactions (Abigail Colley)
- A functionally validated TCR-pMHC database for TCR specificity model development (Bjørn Kwee)
- TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing (Mikhail Pogorelyy)
15:30 - 16:00:
Coffee Break
16:00 - 16:05:
Cellecta sponsored talk
16:05 - 17:05: Short Talks
- Phage display enables machine learning discovery of cancer antigen specific TCRs (Giancarlo Croce)
- TWISTAR: An efficient method to uncover T cell receptor cognate antigen reveals an unexpected dominance of non-mutated antigens specific TCRs in multiple tumor types. (Orian Bricard
- Immunoinformatic Mapping of the Landscape of T-Cell Specificity and Phenotype in Synovial Fluid of Arthritic Diseases (Vincent Van Deuren)
- Single-cell transcriptomics reveals the immune signature of alloreactive T cells associated with lung allograft rejection. (Nicole Mifsud)
17:05 - 18:30:
Poster Session

Evening:

Morning Session:

08:30 - 09:00:
Registration and coffee
09:00 - 09:45:
Analyzing the T cell response to M. tuberculosis infection: Distractopes and other surprises
Mark Davis (Stanford University)
09:45 - 10:30:
CD8 T cell immunodominance
Antonio Lanzavecchia (National Institute of Molecular Genetics, Milan)
10:30 - 10:35:
Parse Biosciences sponsored talk
10:35 - 11:15:
Coffee Break
11:15 - 12:00:
The role of the alpha-beta T cell receptor sequence in defining T cell fate
Soumya Raychaudhuri (Broad Institute)
12:00 - 12:45:
Unravelling T-cell recognition: insights from Immunology and AI
Hashem Koohy (Weatherall Institute of Molecular Medicine)
12:45 - 14:00:
Lunch Break

Afternoon Session:

14:00 - 14:45:
Blood TCR signatures identify and predict autoimmune and inflammatory disease states : promises & challenges for the ATCR meeting
Encarnita Mariotti-Ferrandiz (Sorbonne Université)
14:45 - 15:30:
Assembly and analysis of TCRs in high throughput
Michael Birnbaum (MIT)
15:30 - 16:00:
Coffee Break
16:00 - 16:45:
Deciphering the T cell receptor specificity code
Paul Thomas (St Jude’s Children Hospital)

Evening:

17:45 - 20:00:
Tour and Closing Reception at Antwerp City Hall (limited capacity)