CoPeD

Publications

New approach methodologies for assessing developmental toxicity of pharmaceuticals : case examples and future directions

Source
Reproductive toxicology - ISSN 0890-6238-137 (2025) p. 1-8
Author(s)
    Nicola Powles-Glover, Allen R. Kaczor, Steven Van Cruchten, Christopher J. Bowman, Kimberly C. Brannen, Claudia Demarta-Gatsi, Isabelle LeConte, Amer Jamalpoor, Fumito Mikashima, Shermaine Mitchell-Ryan, Dinesh Stanislaus, Peter Theunissen, Belen Tornesi, Ronald L. Wange, Connie L. Chen

Considerations for use of humanized IgG1/4 Göttingen minipigs in safety assessment of antibody-based therapeutics

Source
Regulatory toxicology and pharmacology - ISSN 0273-2300-161 (2025) p. 1-5
Author(s)
    Anna Engstrom, Tine Dahlbaek Hannibal, Jerome Egli, Beatrice Gauthier, Mikkel Lykke Krarup, Daniela Gallo, Andres Eskjaer Jensen, Steven Van Cruchten, Steven Bulera, Miranda Cornet, Sabine Elisabeth Hammer, David Henry, Bjoern Jacobsen, John Kendrick, Lars Siim Madsen, Sofiene Mhedhbi, Steven Oag, Henrik Duelund Pedersen, Manuela Teti, Pramila Singh

Altered liver sinusoidal endothelial cells in MASLD and their evolution following lanifibranor treatment

Source
JHEP Reports - ISSN 2589-5559-7:6 (2025) p. 1-16
Author(s)

Effects of hypothermia and hypoxia on cytochrome P450-mediated drug metabolism in neonatal Göttingen minipigs

Source
Basic and clinical pharmacology and toxicology - ISSN 1742-7835-135:5 (2024) p. 620-640
Author(s)
    Marina Stroe, Laura De Clerck, Maarten Dhaenens, Rachel Sian Dennis, Dieter Deforce, Sebastien Carpentier, Pieter Annaert, Karen Leys, Anne Smits, Karel Allegaert, Christa Van Ginneken, Steven Van Cruchten