Experimental Neurobiology Unit

Publications

Integrating [¹¹C]methylreboxetine PET and MRI to map in vivo norepinephrine transporter distribution : a proof-of-concept study of noradrenergic vulnerability in neurodegeneration

Source
Nuclear medicine and biology - ISSN 0969-8051-152 (2026) p. 1-9
Author(s)

Limited evidence for heart rate variability as a predictor of cognitive and pathophysiological brain markers

Source
Journal of Alzheimer's disease - ISSN 1387-2877- (2025) p.
Author(s)
    Sofia Marcolini, Jaime D. Mondragon, Arie M. van Roon, Balewgizie Sileshi Tegegne, Harriette Riese, Rozemarijn Vliegenthart, Rudi A.J.O. Dierckx, Ronald H. Borra, Peter Paul De Deyn

Associations of lifestyle factors with amyloid pathology in persons without dementia

Source
Journal of Alzheimer's disease - ISSN 1387-2877-108:3 (2025) p. 1-17
Author(s)
    Julie E. Oomens, Stephanie J.B. Vos, Nancy N. Maserejian, Merce Boada, Mira Didic, Sebastiaan Engelborghs, Tormod Fladby, Wiesje M. van der Flier, Giovanni B. Frisoni, Lutz Froehlich, Kiran Dip Gill, Timo Grimmer, Jakub Hort, Yoshiaki Itoh, Takeshi Iwatsubo, Aleksandra Klimkowicz-Mrowiec, Susan M. Landau, Dong Young Lee, Alberto Lleo, Pablo Martinez-Lage, Alexandre de Mendonca, Philipp T. Meyer, Piero Parchi, Matteo Pardini, Lucilla Parnetti, Julius Popp, Lorena Rami, Eric M. Reiman, Juha O. Rinne, Karen M. Rodrigue, Pascual Sanchez-Juan, Isabel Santana, Nikolaos Scarmeas, Philip Scheltens, Ingmar Skoog, Reisa A. Sperling, Yaakov Stern, Sylvia Villeneuve, Gunhild Waldemar, Jens Wiltfang, Henrik Zetterberg, Daniel Alcolea, Ricardo F. Allegri, Daniele Altomare, Randall J. Bateman, Simone Baiardi, Ines Baldeiras, Kaj Blennow, Anouk den Braber, Willemijn J. Jansen

Real-world brain volumetry in multiple sclerosis : importance of methodological consistency and clinical relevance of gray matter atrophy

Source
Frontiers in neurology - ISSN 1664-2295-16 (2025) p. 1-12
Author(s)
    Joke Temmerman, Ann Vanremoortel, Maria Bjerke, Marie B. D'hooghe, Guy Nagels, Ayla Pauwels, Diana Sima, Dirk Smeets, Jeroen Van Schependom, Mandy Wittens, Sebastiaan Engelborghs, Miguel D'haeseleer

The association of diabetes with Alzheimer's disease biomarkers and vascular burden across European aging and memory clinic cohorts

Source
Alzheimer's & dementia - ISSN 1552-5260-21:10 (2025) p. 1-12
Author(s)
    Veerle Van Gils, Willemijn J. Jansen, Wiesje M. Van Der Flier, Pablo Martinez-lage, Jakub Hort, Inez H.G.B. Ramakers, Olivier Rouaud, Markku Laakso, Sebastiaan Engelborghs, Julius Popp, Alberto Lleo, Anders Wallin, Magda Tsolaki, Charlotte E. Teunissen, Rik Vandenberghe, Yvonne Freund-levi, Lutz Frolich, Henrik Zetterberg, Johannes Streffer, Simon Lovestone, Justine Moonen, Argonde Van Harten, Katerina Veverova, Nienke Legdeur, Anouk Den Braber, Daniel Damian, Anette Hall, Janita Bralten, Giuseppe Fanelli, Barbara Franke, Geert Poelmans, Monica Bullo, Susana Jimenez-murcia, Fernando Fernandez-aranda, Jordi Salas-salvado, Soren Dalsgaard, Pieter Jelle Visser, Stephanie J.B. Vos

Norepinephrine-induced intracellular Ca²+ increase is coupled with astrocytic BK channel activation and capillary response

Source
American journal of physiology : cell physiology - ISSN 0363-6143-329:4 (2025) p. C1061-C1074
Author(s)
    Jelena Bogdanovic Pristov, Danijela Bataveljic, Dunja Bijelic, Katarina Milicevic, Jelena Korac Jacic, Ljiljana Nikolic

Assessing the link between cerebellar volume and cognitive function in Alzheimer's disease : a pilot study

Source
Scientific reports - ISSN 2045-2322-15:1 (2025) p. 1-12
Author(s)
    Deborah Van Rossem, Gert-Jan Allemeersch, Nuno Barros, Joke Temmerman, Marijke Desmet, Ilka Ringoot, Annemie Ribbens, Veronique Michiels, Johan De Mey, Chris Baeken, Sebastiaan Engelborghs, Sara De Witte

Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease

Source
Alzheimer's & dementia - ISSN 1552-5260-21:10 (2025) p. 1-13
Author(s)
    Eleonora M. Vromen, Senne B. Lageman, Johan Gobom, Rik van der Kant, Valerija Dobricic, Lars Bertram, Johannes Streffer, Simon Lovestone, Stephanie J.B. Vos, Mikel Tainta, Yvonne Freund-Levi, Lutz Frolich, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Frans Verhey, Rik Vandenberghe, Jolien Schaeverbeke, Kaj Blennow, Sven J. van der Lee, Philip Scheltens, Yolande A.L. Pijnenburg, Wiesje M. van der Flier, Charlotte E. Teunissen, Henrik Zetterberg, Pieter Jelle Visser, Betty Tijms

Systemic inflammation as a central player in the initiation and development of Alzheimer's disease

Source
Immunity & ageing - ISSN 1742-4933-22:1 (2025) p. 1-26
Author(s)

Safety and immunogenicity of two Tau-targeting active immunotherapies, ACI-35.030 and JACI-35.054, in participants with early Alzheimer's disease : a phase 1b/2a, multicentre, double-blind, randomised, placebo-controlled study

Source
EBioMedicine - ISSN 2352-3964-120 (2025) p. 1-16
Author(s)
    Olivier Sol, Julien Mermoud, Merja Hallikainen, Sudhir Ku, Juha Rinne, Paul Dautzenberg, Everard G.B. Vijverberg, Catherine Mummery, Anne Borjesson-Hanson, Michael Jonsson, Craig Ritchie, Catherine Pennington, Marija Vukicevic, Eva Gollwitzer, Emma Fiorini, David T. Hickman, Valerie Hliva, Julian Gray, Viktoriia Gerasymchuk, Jonathan Wagg, Nicolas Fournier, Benedicte Le, Iva Kezic, Lennert Steukers, Gallen Triana-Baltzer, Clara Theunis, Johannes Streffer, Marie Kosco-Vilbois, Andrea Pfeifer, Philip Scheltens

Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia

Source
Molecular neurodegeneration - ISSN 1750-1326-20:1 (2025) p. 1-17
Author(s)
    Yanaika S. Hok-A-Hin, Lisa Vermunt, Carel F.W. Peeters, Emma L. van der Ende, Sterre C.M. de Boer, Lieke H. Meeter, Julie de Houwer, Harro Seelaar, John C. van Swieten, William T. Hu, Alberto Lleo, Daniel Alcolea, Sebastiaan Engelborghs, Anne Sieben, Alice Chen-Plotkin, David J. Irwin, Wiesje M. van der Flier, Yolande A.L. Pijnenburg, Charlotte E. Teunissen, Marta del Campo

Comment by European Alzheimer's Disease Consortium (EADC) investigators on the negative recommendation of the CHMP on the marketing authorization of donanemab for early Alzheimer' s disease

Source
Journal of Prevention of Alzheimer's Disease - ISSN 2274-5807-12:8 (2025) p. 1-5
Author(s)
    Frank Jessen, Javier Arbizu, Merce Boada, Mircea Balasa, Karim Bennys, Marina Boban, Katharina Burger, Andrea Chincarini, Annachiara Cagnin, Peter Paul De Deyn, Emrah Duezel, Sebastiaan Engelborghs, Michael Ewers, Lieza G. Exalto, Wiesje M. van der Flier, Juan Fortea, Kristian Steen Frederiksen, Giovanni B. Frisoni, Lutz Froelich, Alejandro J. Garza-Martinez, Timo Grimmer, Bernard Hanseeuw, Jakub Hort, Adrian Ivanoiu, Patrick G. Kehoe, Sean P. Kennelly, Silke Kern, Stefan Kloeppel, Lenka Krajcovicova, Milica G. Kramberger, Bernadette McGuinness, Patrizia Mecocci, Timo Jan Oberstein, Pierre-Jean Ousset, Claire Paquet, Robert Perneczky, Fabrizio Piazza, Domenico Plantone, Innocenzo Rainero, Guillaume Sacco, Eric Salm, Isabel Santana, Nikolaos Scarmeas, Anja Schneider, Jonathan M. Schott, Eino Solje, Elka Stefanova, Elisabeth Stogmann, Melanie Strauss, Bengt Winblad

Disease progression biomarkers in multiple sclerosis : paving the way towards implementation in clinical practice

Source
Antwerp, University of Antwerp & Vrije Universiteit Brussel, 2025,iv, v, 184 p.
Author(s)

Modulating language and executive functions in bilingual aphasia with cerebellar tDCS : a case series

Source
Brain and language - ISSN 0093-934X-269 (2025) p. 1-17
Author(s)