Systemic inflammation as a central player in the initiation and development of Alzheimer's disease

Source
Immunity & ageing - ISSN 1742-4933-22:1 (2025) p. 1-26
Author(s)

Safety and immunogenicity of two Tau-targeting active immunotherapies, ACI-35.030 and JACI-35.054, in participants with early Alzheimer's disease : a phase 1b/2a, multicentre, double-blind, randomised, placebo-controlled study

Source
EBioMedicine - ISSN 2352-3964-120 (2025) p. 1-16
Author(s)
    Olivier Sol, Julien Mermoud, Merja Hallikainen, Sudhir Ku, Juha Rinne, Paul Dautzenberg, Everard G.B. Vijverberg, Catherine Mummery, Anne Borjesson-Hanson, Michael Jonsson, Craig Ritchie, Catherine Pennington, Marija Vukicevic, Eva Gollwitzer, Emma Fiorini, David T. Hickman, Valerie Hliva, Julian Gray, Viktoriia Gerasymchuk, Jonathan Wagg, Nicolas Fournier, Benedicte Le, Iva Kezic, Lennert Steukers, Gallen Triana-Baltzer, Clara Theunis, Johannes Streffer, Marie Kosco-Vilbois, Andrea Pfeifer, Philip Scheltens

Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia

Source
Molecular neurodegeneration - ISSN 1750-1326-20:1 (2025) p. 1-17
Author(s)
    Yanaika S. Hok-A-Hin, Lisa Vermunt, Carel F.W. Peeters, Emma L. van der Ende, Sterre C.M. de Boer, Lieke H. Meeter, Julie de Houwer, Harro Seelaar, John C. van Swieten, William T. Hu, Alberto Lleo, Daniel Alcolea, Sebastiaan Engelborghs, Anne Sieben, Alice Chen-Plotkin, David J. Irwin, Wiesje M. van der Flier, Yolande A.L. Pijnenburg, Charlotte E. Teunissen, Marta del Campo

Comment by European Alzheimer's Disease Consortium (EADC) investigators on the negative recommendation of the CHMP on the marketing authorization of donanemab for early Alzheimer' s disease

Source
Journal of Prevention of Alzheimer's Disease - ISSN 2274-5807-12:8 (2025) p. 1-5
Author(s)
    Frank Jessen, Javier Arbizu, Merce Boada, Mircea Balasa, Karim Bennys, Marina Boban, Katharina Burger, Andrea Chincarini, Annachiara Cagnin, Peter Paul De Deyn, Emrah Duezel, Sebastiaan Engelborghs, Michael Ewers, Lieza G. Exalto, Wiesje M. van der Flier, Juan Fortea, Kristian Steen Frederiksen, Giovanni B. Frisoni, Lutz Froelich, Alejandro J. Garza-Martinez, Timo Grimmer, Bernard Hanseeuw, Jakub Hort, Adrian Ivanoiu, Patrick G. Kehoe, Sean P. Kennelly, Silke Kern, Stefan Kloeppel, Lenka Krajcovicova, Milica G. Kramberger, Bernadette McGuinness, Patrizia Mecocci, Timo Jan Oberstein, Pierre-Jean Ousset, Claire Paquet, Robert Perneczky, Fabrizio Piazza, Domenico Plantone, Innocenzo Rainero, Guillaume Sacco, Eric Salm, Isabel Santana, Nikolaos Scarmeas, Anja Schneider, Jonathan M. Schott, Eino Solje, Elka Stefanova, Elisabeth Stogmann, Melanie Strauss, Bengt Winblad

Disease progression biomarkers in multiple sclerosis : paving the way towards implementation in clinical practice

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Antwerp, University of Antwerp & Vrije Universiteit Brussel, 2025,iv, v, 184 p.
Author(s)

Modulating language and executive functions in bilingual aphasia with cerebellar tDCS : a case series

Source
Brain and language - ISSN 0093-934X-269 (2025) p. 1-17
Author(s)

Independent validation and outlier analysis of EuroPOND alzheimer's disease staging model using ADNI and real-world clinical data

Source
Alzheimer's research & therapy - ISSN 1758-9193-17:1 (2025) p. 1-15
Author(s)
    Mandy Wittens, Diana M. Sima, Arne Brys, Hanne Struyfs, Ellis Niemantsverdriet, Ellen De Roeck, Christine Bastin, Florence Benoit, Bruno Bergmans, Jean-Christophe Bier, Peter Paul De Deyn, Olivier Deryck, Bernard Hanseeuw, Adrian Ivanoiu, Gaetane Picard, Eric Salmon, Kurt Segers, Anne Sieben, Evert Thiery, Jos Tournoy, Anne-Marie van Binst, Jan Versijpt, Dirk Smeets, Maria Bjerke, Maura Bellio, Neil P. Oxtoby, Daniel C. Alexander, Annemie Ribbens, Sebastiaan Engelborghs

Navigating the introduction of anti-amyloid therapy in Europe : a position statement by individual members of the EADC

Source
Alzheimer's research & therapy - ISSN 1758-9193-17:1 (2025) p. 1-9
Author(s)
    Kristian S. Frederiksen, Merce Boada, Bruno Dubois, Sebastiaan Engelborghs, Giovanni B. Frisoni, Jean Georges, Jakub Hort, Linus Joensson, Milica G. Kramberger, Pierre-Jean Ousset, Nikolaos Scarmeas, Reinhold Schmidt, Jonathan M. Schott, Luiza Spiro, Gunhild Waldemar, Bengt Winblad, Frank Jessen, Lutz Frölich

Monoaminergic alterations at the subregional cervical and thoracic spinal cord level of patients within the FTD-ALS continuum and early-onset AD : low thoracic dopaminergic activity in ALS

Source
Journal of neurochemistry - ISSN 0022-3042-169:3 (2025) p. 1-18
Author(s)

Increased TMEM106B levels lead to lysosomal dysfunction which affects synaptic signaling and neuronal health

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Molecular neurodegeneration - ISSN 1750-1326-20:1 (2025) p. 1-26
Author(s)

Synaptic protein CSF levels relate to memory scores in individuals without dementia

Source
Alzheimer's research & therapy - ISSN 1758-9193-17:1 (2025) p. 1-15
Author(s)
    Kirsten E.J. Wesenhagen, Diederick M. de Leeuw, Jori Tomassen, Johan Gobom, Isabelle Bos, Stephanie J.B. Vos, Pablo Martinez-Lage, Mikel Tainta, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Rik Vandenberghe, Yvonne Freund-Levi, Frans Verhey, Simon Lovestone, Johannes Streffer, Valerija Dobricic, Kaj Blennow, Philip Scheltens, August B. Smit, Lars Bertram, Charlotte E. Teunissen, Henrik Zetterberg, Betty M. Tijms, Pieter Jelle Visser

Copy number variation and haplotype analysis of 17q21.31 reveals increased risk associated with progressive supranuclear palsy and gene expression changes in neuronal cells

Source
Movement disorders: video, videotape supplements - ISSN 0885-3185-40:5 (2025) p. 950-961
Author(s)
    Hui Wang, Timothy S. Chang, Beth A. Dombroski, Po-Liang Cheng, Ya-Qin Si, Albert Tucci, Vishakha Patil, Leopoldo Valiente-Banuet, Chong Li, Kurt Farrell, Catriona Mclean, Laura Molina-Porcel, Alex Rajput, Peter Paul De Deyn, Nathalie Le Bastard, Marla Gearing, Laura Donker Kaat, John C. Van Swieten, Elise Dopper, Bernardino F. Ghetti, Kathy L. Newell, Claire Troakes, Justo G. de Yebenes, Alberto Rabano-Gutierrez, Tina Meller, Wolfgang H. Oertel, Gesine Respondek, Maria Stamelou, Thomas Arzberger, Sigrun Roeber, Ulrich Mueller, Franziska Hopfner, Pau Pastor, Alexis Brice, Alexandra Durr, Isabelle Le Ber, Thomas G. Beach, Geidy E. Serrano, Lili-Naz Hazrati, Irene Litvan, Rosa Rademakers, Owen A. Ross, Douglas Galasko, Adam L. Boxer, Bruce L. Miller, Willian W. Seeley, Vivianna M. Van Deerlin, Edward B. Lee, Charles L. White, Wan-Ping Lee