Experimental Neurobiology Unit

Publications

Experimental Neurobiology Unit

Systemic inflammation as a central player in the initiation and development of Alzheimer's disease

Source
Immunity & ageing - ISSN 1742-4933-22:1 (2025) p. 1-26
Author(s)

Safety and immunogenicity of two Tau-targeting active immunotherapies, ACI-35.030 and JACI-35.054, in participants with early Alzheimer's disease : a phase 1b/2a, multicentre, double-blind, randomised, placebo-controlled study

Source
EBioMedicine - ISSN 2352-3964-120 (2025) p. 1-16
Author(s)
    Olivier Sol, Julien Mermoud, Merja Hallikainen, Sudhir Ku, Juha Rinne, Paul Dautzenberg, Everard G.B. Vijverberg, Catherine Mummery, Anne Borjesson-Hanson, Michael Jonsson, Craig Ritchie, Catherine Pennington, Marija Vukicevic, Eva Gollwitzer, Emma Fiorini, David T. Hickman, Valerie Hliva, Julian Gray, Viktoriia Gerasymchuk, Jonathan Wagg, Nicolas Fournier, Benedicte Le, Iva Kezic, Lennert Steukers, Gallen Triana-Baltzer, Clara Theunis, Johannes Streffer, Marie Kosco-Vilbois, Andrea Pfeifer, Philip Scheltens

Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia

Source
Molecular neurodegeneration - ISSN 1750-1326-20:1 (2025) p. 1-17
Author(s)
    Yanaika S. Hok-A-Hin, Lisa Vermunt, Carel F.W. Peeters, Emma L. van der Ende, Sterre C.M. de Boer, Lieke H. Meeter, Julie de Houwer, Harro Seelaar, John C. van Swieten, William T. Hu, Alberto Lleo, Daniel Alcolea, Sebastiaan Engelborghs, Anne Sieben, Alice Chen-Plotkin, David J. Irwin, Wiesje M. van der Flier, Yolande A.L. Pijnenburg, Charlotte E. Teunissen, Marta del Campo

Comment by European Alzheimer's Disease Consortium (EADC) investigators on the negative recommendation of the CHMP on the marketing authorization of donanemab for early Alzheimer' s disease

Source
Journal of Prevention of Alzheimer's Disease - ISSN 2274-5807-12:8 (2025) p. 1-5
Author(s)
    Frank Jessen, Javier Arbizu, Merce Boada, Mircea Balasa, Karim Bennys, Marina Boban, Katharina Burger, Andrea Chincarini, Annachiara Cagnin, Peter Paul De Deyn, Emrah Duezel, Sebastiaan Engelborghs, Michael Ewers, Lieza G. Exalto, Wiesje M. van der Flier, Juan Fortea, Kristian Steen Frederiksen, Giovanni B. Frisoni, Lutz Froelich, Alejandro J. Garza-Martinez, Timo Grimmer, Bernard Hanseeuw, Jakub Hort, Adrian Ivanoiu, Patrick G. Kehoe, Sean P. Kennelly, Silke Kern, Stefan Kloeppel, Lenka Krajcovicova, Milica G. Kramberger, Bernadette McGuinness, Patrizia Mecocci, Timo Jan Oberstein, Pierre-Jean Ousset, Claire Paquet, Robert Perneczky, Fabrizio Piazza, Domenico Plantone, Innocenzo Rainero, Guillaume Sacco, Eric Salm, Isabel Santana, Nikolaos Scarmeas, Anja Schneider, Jonathan M. Schott, Eino Solje, Elka Stefanova, Elisabeth Stogmann, Melanie Strauss, Bengt Winblad

Disease progression biomarkers in multiple sclerosis : paving the way towards implementation in clinical practice

Source
Antwerp, University of Antwerp & Vrije Universiteit Brussel, 2025,iv, v, 184 p.
Author(s)

Neurochemistry and Behaviour

Short- and long-term functional connectivity differences associated with Alzheimer’s disease progression

Source
Dementia and geriatric cognitive disorders extra - ISSN 1664-5464-11:3 (2021) p. 235-249
Author(s)

Genome-wide association study of frontotemporal dementia identifies a C9ORF72 haplotype with a median of 12-G4C2 repeats that predisposes to pathological repeat expansions

Source
Translational psychiatry - ISSN 2158-3188-11:1 (2021) p.
Author(s)
    Lianne M. Reus, Iris E. Jansen, Merel O. Mol, Fred van Ruissen, Jeroen van Rooij, Natasja M. van Schoor, Niccolo Tesi, Marcel J.T. Reinders, Martijn A. Huisman, Henne Holstege, Pieter Jelle Visser, Sterre C.M. de Boer, Marc Hulsman, Shahzad Ahmad, Najaf Amin, Andre G. Uitterlinden, Arfan Ikram, Cornelia M. van Duijn, Harro Seelaar, Inez H.G.B. Ramakers, Frans R. J. Verhey, Aad van der Lugt, Jurgen A.H.R. Claassen, Geert Jan Biessels, Peter Paul De Deyn, Philip Scheltens, Wiesje M. van der Flier, John C. van Swieten, Yolande A. L. Pijnenburg, Sven J. van der Lee

Knowledge, health beliefs and attitudes towards dementia and dementia risk reduction among descendants of people with dementia : a qualitative study using focus group discussions

Source
BMC public health - ISSN 1471-2458-21:1 (2021) p.
Author(s)
    J. Vrijsen, E.L.M. Maeckelberghe, R. Broekstra, J.J. de Vries, A. Abu-Hanna, Peter Paul De Deyn, R.C. Oude Voshaar, F E. Reesink, E. Buskens, S.E. de Rooij, N. Smidt

Pain processing in older adults with dementia-related cognitive impairment is associated with frontal neurodegeneration

Source
Neurobiology of aging - ISSN 0197-4580-106 (2021) p. 139-152
Author(s)
    Steffie Bunk, Sytse Zuidema, Kathrin Koch, Stefan Lautenbacher, Peter Paul De Deyn, Miriam Kunz

Neuronal Circuit Research

Constitutive, basal, and beta-alanine-mediated activation of the human mas-related G protein-coupled receptor D induces release of the inflammatory cytokine IL-6 and is dependent on NF-kappa B signaling

Source
International journal of molecular sciences - ISSN 1422-0067-22:24 (2021) p.
Author(s)

Suitability of hSC and hiPSC derived cardiomyocytes as in vitro cell model that represents the physiological conditions for cardiotoxicity screening

Source
Antwerp, University of Antwerp, Faculty of Pharmaceutical, Biomedical and Veterinary sciences, Department of Biomedical sciences, 2021,190 p.
Author(s)

Impaired cytoplasmic domain interactions cause co-assembly defect and loss of function in the p.Glu293Lys KNCJ2 variant isolated from an Andersen-Tawil syndrome patient

Source
Cardiovascular research - ISSN 0008-6363-117:8 (2021) p. 1923-1934
Author(s)
    Szilvia Deri, Janos Borbas, Teodora Hartai, Lidia Hategan, Beata Csanyi, Adam Visnyovszki, Tamara Madacsy, Jozsef Maleth, Zoltan Hegedus, Istvan Nagy, Rohit Arora, Alain Labro, Laszlo Kornyei, Andras Varro, Robert Sepp, Balazs Ordog