The simplest method yet for ultrafast desalting of proteins and oligonucleotides in native mass spectrometry

Source
Analytical chemistry - ISSN 0003-2700-98:5 (2026) p. 3723-3731
Author(s)
    Edvaldo V.S. Maciel, Jonathan Eisert, Christian Hake, Alexander Schiesser, Frederik Lermyte

Introducing a CATALYST to accelerate native affinity selection mass spectrometry

Source
Journal of the American Society for Mass Spectrometry - ISSN 1044-0305-37:2 (2026) p. 396-406
Author(s)
    Jonathan Eisert, Edvaldo Vasconcelos Soares Maciel, Roman Grigoriev, Ilie Victor Hurbean, Leonard Kuhl, Luca Panholzer, Katharina Speh, Frederik Lermyte

Toward anti-herpesviral PROTACs : assessing the challenges for targeted protein degradation on the example of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen

Source
ChemMedChem - ISSN 1860-7179-21:1 (2026) p. 1-13
Author(s)
    Aylin Berwanger, Saskia Catherina Stein, Sarah Brandner, Andreas Martin Kany, Sebastian Heinz, Brigitta Loretz, Claus-michael Lehr, Anna Katharina Herta Hirsch, Frederik Lermyte, Thomas Friedrich Schulz, Martin Empting

Native Taylor/non-Taylor dispersion-mass spectrometry (TNT-MS) allows rapid protein desalting and multiplexed, label-free ligand screening

Source
Small methods - ISSN 2366-9608-10:2 (2026) p. 1-10
Author(s)
    Jonathan Eisert, Edvaldo Vasconcelos Soares Maciel, Verena Dederer, Aylin Berwanger, Henry J. Bailey, Ivan Dikic, Stefan Knapp, Martin Empting, Sebastian Mathea, Henrik Jensen, Frederik Lermyte

Self-packed size-exclusion columns enable versatile high-throughput native, top-down, and ion mobility-mass spectrometry studies on proteins and complexes

Source
Talanta : the international journal of pure and applied analytical chemistry - ISSN 0039-9140-291 (2025) p. 1-10
Author(s)
    Edvaldo Vasconcelos Soares Maciel, Tanja Habeck, Christian Meyners, Frederik Lermyte