C9orf72 hexanucleotide repeat expansions impair microglial response in ALS

Source
Nature neuroscience - ISSN 1097-6256- (2025) p.
Author(s)

Prematurely aged human microglia exhibit impaired stress response and defective nucleocytoplasmic shuttling of ALS associated FUS

Source
Aging Cell - ISSN 1474-9718- (2025) p.
Author(s)
    Christiane Hartmann, Christina Hass, Muriel Knobloch, Israel Barrantes, Laura Fumagalli, Jessie Premereur, Franz Markert, Maite Peters, Georgia Koromila, Alexander Hartmann, Kathrin Jaeger, Jette Abel, Renzo Mancuso, Alexander Storch, Michael Walter, Georg Fuellen, Andreas Hermann

Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease

Source
Molecular neurodegeneration - ISSN 1750-1326-19:1 (2024) p. 1-25
Author(s)

A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons

Source
Acta neuropathologica communications - ISSN 2051-5960-11:1 (2023) p. 1-22
Author(s)
    Jimmy Beckers, Arun Kumar Tharkeshwar, Laura Fumagalli, Matilde Contardo, Evelien Van Schoor, Raheem Fazal, Dietmar Rudolf Thal, Siddharthan Chandran, Renzo Mancuso, Ludo Van Den Bosch, Philip Van Damme