The fast-dissociating D₂ antagonist antipsychotic JNJ-37822681 is a neuronal Kv7 channel opener : potential repurposing for epilepsy treatment

Source
British journal of pharmacology - ISSN 0007-1188- (2025) p.
Author(s)
    Lidia Carotenuto, Oliver Keminer, Giusy Carleo, Andrea Zaliani, Antonio Leo, Rita Citraro, Giovambattista De Sarro, Nina Dirkx, Mark Kaji, Sarah Weckhuysen, Jeanette Reinshagen, Vincenzo Barrese, Natascia Guida, Carmine Ostacolo, Francesco Miceli, Philip Gribbon, Maurizio Taglialatela

Structural mechanism underlying the differential effects of ivermectin and moxidectin on the C. elegans glutamate-gated chloride channel GLC-2

Source
Biomedicine and pharmacotherapy - ISSN 0753-3322-145 (2022) p. 1-12
Author(s)
    Mark Kaji, Jennifer D. Noonan, Timothy G. Geary, Robin N. Beech