Renzo Mancuso associate research professor

Publications Renzo Mancuso

The APOE isoforms differentially shape the transcriptomic and epigenomic landscapes of human microglia xenografted into a mouse model of Alzheimer's disease

Source
Nature communications - ISSN 2041-1723-16:1 (2025) p. 1-15
Author(s)

Neuroinflammation in Alzheimer disease

Source
Nature reviews immunology - ISSN 1474-1733-25 (2024) p. 321-352
Author(s)
    Michael T. Heneka, Wiesje M. van der Flier, Frank Jessen, Jeroen Hoozemanns, Dietmar R Thal, Delphine Boche, Frederic Brosseron, Charlotte Teunissen, Henrik Zetterberg, Andreas H. Jacobs, Paul Edison, Alfredo Ramirez, Carlos Cruchaga, Jean-Charles Lambert, Agustin Ruiz Laza, Jose Vicente Sanchez-Mut, Andre Fischer, Sergio Castro-Gomez, Thor D. Stein, Luca Kleineidam, Michael Wagner, Jonas J. Neher, Colm Cunningham, Sim K. Singhrao, Marco Prinz, Christopher K. Glass, Johannes C.M. Schlachetzki, Oleg Butovsky, Kilian Kleemann, Philip L. De Jaeger, Hannah Scheiblich, Guy C. Brown, Gary Landreth, Miguel Moutinho, Jaime Grutzendler, Diego Gomez-Nicola, Roisin M. McManus, Katrin Andreasson, Christina Ising, Deniz Karabag, Darren J. Baker, Shane A. Liddelow, Alexei Verkhratsky, Malu Tansey, Alon Monsonego, Ludwig Aigner, Guillaume Dorothee, Klaus-Armin Nave, Renzo Mancuso, Sean-Patrick Riechers

APOE from astrocytes restores Alzheimer's Aβ-pathology and DAM-like responses in APOE deficient microglia

Source
EMBO molecular medicine - ISSN 1757-4676-16:12 (2024) p. 3113-3141
Author(s)
    Pranav Preman, Daan Moechars, Emre Fertan, Leen Wolfs, Lutgarde Serneels, Disha Shah, Jochen Lamote, Suresh Poovathingal, An Snellinx, Renzo Mancuso, Sriram Balusu, David Klenerman, Amaia M. Arranz, Mark Fiers, Bart De Strooper

Deep proteomic analysis of microglia reveals fundamental biological differences between model systems

Source
Cell reports - ISSN 2211-1247-43:11 (2024) p. 1-22
Author(s)
    Amy F. Lloyd, Anna Martinez-Muriana, Emma Davis, Michael J.D. Daniels, Pengfei Hou, Renzo Mancuso, Alejandro J. Brenes, Linda V. Sinclair, Ivana Geric, An Snellinx, Katleen Craessaerts, Tom Theys, Mark Fiers, Bart De Strooper, Andrew J.M. Howden