Sebastiaan De Schepper TT. asst. research professor

Publications Sebastiaan De Schepper

Intestinal macrophages modulate synucleinopathy along the gut-brain axis

Source
Nature - ISSN 0028-0836- (2026) p.
Author(s)
    Sebastiaan De Schepper, Viktoras Konstantellos, James A. Conway, Dimitra Sokolova, Ludovica Zaccagnini, Matthew V. Cowley, Annerieke Sierksma, Maria Yudina, Marisa Edmonds, Daria Gavriouchkina, Bethany Geary, Amber Wallis, Meral Celikag, Zeynep Baykam, Monica Vara-Perez, Gerard Crowley, Fabian Tobias Hager, Mitchell Bijnen, David Posner, Kelvin Luk, Vuk Cerovic, Menna Clatworthy, Elizabeth J. Videlock, Zane Jaunmuktane, Kiavash Movahedi, Melanie Greter, Benny Chain, Dario R. Alessi, Soyon Hong, Tim Bartels

C1q and immunoglobulins mediate activity-dependent synapse loss in the adult brain

Source
- () p.
Author(s)
    Gerard Crowley, EMir Turkes, Kim Minjung, Sebastiaan De Schepper, Benjy J.Y. Tan, Javier Rueda-Carrasco, Margarita Toneva, John Christian Fajardo, Judy Ze Ge, Zhengyue Grace Yang

Astrocyte-derived MFG-E8 facilitates microglial synapse elimination in Alzheimer's disease mouse models

Source
bioRxiv - ISSN 2692-8205- (2024) p.
Author(s)
    Dimitra Sokolova, Shari Addington Ghansah, Francesca Puletti, Tatiana Georgiades, Sebastiaan De Schepper, Yongjing Zheng, Gerard Crowley, Ling Wu, Javier Rueda-Carrasco, Angeliki Koutsiouroumpa, Philip Muckett, Oliver J. Freeman, Baljit S. Khakh, Soyon Hong

Microglia‐synapse engulfment via PtdSer‐TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models

Source
The EMBO journal - ISSN 1460-2075-42:19 (2024) p. 1-18
Author(s)
    Javier Rueda-Carrasco, Dimitra Sokolova, Sang-Eun Lee, Thomas Childs, Natália Jurčáková, Gerard Crowley, Sebastiaan De Schepper, Judy Z. Ge, Joanne I. Lachica, Christina E. Toomey, Oliver J. Freeman, John Hardy, Samuel J. Barnes, Tammaryn Lashley, Beth Stevens, Sunghoe Chang, Soyon Hong

Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease

Source
Nature neuroscience - ISSN 1546-1726-26:3 (2023) p. 406-415
Author(s)
    Sebastiaan De Schepper, Judy Z. Ge, Gerard Crowley, Laís S.S. Ferreira, Dylan Garceau, Christina E. Toomey, Dimitra Sokolova, Javier Rueda-Carrasco, Sun-Hye Shin, Jung-Seok Kim, Thomas Childs, Tammaryn Lashley, Jemima J. Burden, Michael Sasner, Carlo Sala Frigerio, Steffen Jung, Soyon Hong