Wouter De Coster postdoc researcher FWO

Publications Wouter De Coster

Expanding the spectrum of annexin A11 proteinopathy in frontotemporal lobar degeneration and motor neuron disease

Source
Acta neuropathologica - ISSN 0001-6322-150:1 (2025) p. 1-19
Author(s)
    Nikhil B. Ghayal, Richard J. Crook, Angita Jain, Gunveen Sachdeva, Peizhou Jiang, Shanu F. Roemer, Hiroaki Sekiya, Michael A. Deture, Matthew C. Baker, Wouter De Coster, Bjorn Oskarsson, Keith A. Josephs, Rosa Rademakers, Marka M. Van Blitterswijk, Dennis W. Dickson

Methylome analysis of FTLD patients with TDP-43 pathology identifies epigenetic signatures specific to pathological subtypes

Source
Molecular neurodegeneration - ISSN 1750-1326-20:1 (2025) p. 1-27
Author(s)

Brain transcriptomics highlight abundant gene expression and splicing alterations in non-neuronal cells in aFTLD-U

Source
Acta neuropathologica - ISSN 1432-0533-150:1 (2025) p. 1-17
Author(s)
    Sara Alidadiani, Júlia Faura Llorens, Sarah Wynants, Nele Peeters, Marleen Van den Broeck, Linus De Witte, Rafaela Policarpo, Simon Cheung, Cyril Pottier, Nikhil B. Ghayal, Merel O. Mol, Marka van Blitterswijk, Evan Udine, Mariely DeJesus-Hernandez, Matthew Baker, NiCole A. Finch, Yan W. Asmann, Jeroen G.J. van Rooij, Aivi T. Nguyen, R. Ross Reichard, Alissa L. Nana, Oscar L. Lopez, Adam L. Boxer, Howard J. Rosen, Salvatore Spina, Jochen Herms, Keith A. Josephs, Ronald C. Petersen, Robert A. Rissman, Annie Hiniker, Lee-Cyn Ang, Lea T. Grinberg, Glenda M. Halliday, Bradley F. Boeve, Neill R. Graff-Radford, Harro Seelaar, Manuela Neumann, Julia Kofler, Charles L. White, William W. Seeley, John C. van Swieten, Dennis W. Dickson, Ian R.A. Mackenzie, Wouter De Coster, Rosa Rademakers

Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing

Source
Nature communications - ISSN 2041-1723-16:1 (2025) p. 1-19
Author(s)
    Cyril Pottier, Fahri Küçükali, Matt Baker, Anthony Batzler, Gregory D. Jenkins, Marka van Blitterswijk, Cristina Vicente, Wouter De Coster, Sarah Wynants, Pieter Van de Walle, Owen A. Ross, Melissa E. Murray, Júlia Faura Llorens, Stephen J. Haggarty, Jeroen GJ. van Rooij, Merel O. Mol, Ging-Yuek R. Hsiung, Caroline Graff, Linn Oeijerstedt, Manuela Neumann, Yan Asmann, Shannon K. Mcdonnell, Saurabh Baheti, Keith A. Josephs, Jennifer L. Whitwell, Kevin F. Bieniek, Leah Forsberg, Hilary Heuer, Argentina Lario Lago, Ethan G. Geier, Jennifer S. Yokoyama, Alexis P. Oddi, Margaret Flanagan, Qinwen Mao, John R. Hodges, John B. Kwok, Kimiko Domoto-Reilly, Matthis Synofzik, Carlo Wilke, Chiadi Onyike, Bradford C. Dickerson, Bret M. Evers, Brittany N. Dugger, David G. Munoz, Julia Keith, Lorne Zinman, Ekaterina Rogaeva, Eunran Suh, Kristel Sleegers, Rosa Rademakers

Increased TMEM106B levels lead to lysosomal dysfunction which affects synaptic signaling and neuronal health

Source
Molecular neurodegeneration - ISSN 1750-1326-20:1 (2025) p. 1-26
Author(s)