2024

Charles Van Assche, Dustin Krüger, Bryn Flinders, Michiel Vandenbosch, Constantijn Franssen, Pieter-Jan Guns, Ron M A Heeren, Berta Cillero-Pastor. Improved on-tissue detection of the anti-cancer agent doxorubicin by quantitative matrix-assisted laser desorption/ionization mass spectrometry imagingTalanta. 2024 Volume 271, 1 May 2024, 125667DOI: 10.1016/j.talanta.2024.125667Open Access

Hanne M. Boen, Martina Cherubin, Constantijn Franssen, Andreas B. Gevaert, Isabel Witvrouwen, Matthias Bosman, Pieter-Jan Guns, Hein Heidbuchel, Bart Loeys, Maaike Alaerts, and Emeline M. Van Craenenbroeck. Circulating MicroRNA as Biomarkers of Anthracycline-Induced Cardiotoxicity: JACC: CardioOncology State-of-the-Art ReviewJ Am Coll Cardiol CardioOnc. Feb 27, 2024. DOI: 10.1016/j.jaccao.2023.12.009Open Access

2023

Patrizia Pannucci, Marieke Van Daele, Samantha L. Cooper, Edward S. Wragg, Julie March, Marleen Groenen, Stephen J. Hill, Jeanette Woolard. Role of endothelin ETA receptors in the hypertension induced by the VEGFR-2 kinase inhibitors axitinib and lenvatinib in conscious freely-moving ratsBiochemical Pharmacology, 2023, 116007. DOI: 10.1016/j.bcp.2023.116007Open Access

Cédric H.G. Neutel, Callan D. Wesley, Melissa Van Praet, Celine Civati, Lynn Roth, Guido R.Y. De Meyer, Wim Martinet, Pieter-Jan Guns. Empagliflozin decreases ageing-associated arterial stiffening and vascular fibrosis under normoglycemic conditions. Vascular Pharmacology, Vol. 152, October 2023, 107212. DOI: 10.1016/j.vph.2023.107212. Open Access

Elham Ataei Alizadeh, Sara Costa Faya, Haibo Liu, Damiano Lombardi, Sylvain Bernasconi, Pieter-Jan Guns and Michael Markert. Comparison of statistical, machine learning, and mathematical modelling methods to investigate the effect of ageing on dog’s cardiovascular system. ESAIM: Proceedings and Surveys, September 2023, Vol. 73, p. 2-27. DOI: 10.1051/proc/202373002. Open Access

Matthias Bosman, Dustin Krüger, Charles Van Assche, Hanne Boen, Cédric Neutel, Kasper Favere, Constantijn Franssen, Wim Martinet, Lynn Roth, Guido R Y De Meyer, Berta Cillero-Pastor, Leen Delrue, Ward Heggermont, Emeline M Van Craenenbroeck, Pieter-Jan Guns. Doxorubicin-induced cardiovascular toxicity: a longitudinal evaluation of functional and molecular marker. Cardiovascular Research, cvad 136, 2023. DOI: 10.1093/cvr/cvad136. Open Access

Elham Ataei Alizadeh, Georg Rast, Chris Cantow, Jessica Schiwon, Florian Krause, Guido R.Y. De Meyer, Pieter-Jan Guns, Brian D. Guth, Michael Markert. Optimization of bioanalysis of dried blood samples. 107296, 2023. Journal of Pharmacological and Toxicological Methods. DOI: 10.1016/j.vascn.2023.107296  Open Access

Marieke Van Daele, Laura E. Kilpatrick, Jeanette Woolard, Stephen J. Hill. Characterisation of tyrosine kinase inhibitor-receptor interactions at VEGFR2 using sunitinib-red and nanoBRET. Vol. 214, August 2023, 115672. Biochemical Pharmacology. DOI: 10.1016/j.bcp.2023.115672. Open Access

Elham Ataei Alizadeh, Karin Graf, Jessica Schiwon, Thomas Trautmann, Florian Krause, Werner Mayer, Katrin Christ, Eric Martel, Brian D. Guth, Michael Markert. Thirty years of telemetry-based data acquisition for cardiovascular drug safety evaluation: Applications and optimization. Journal of Pharmacological and Toxicological Methods. Vol. 122, July–August 2023, 107279. DOI: 10.1016/j.vascn.2023.107279. Open Access

Elham Ataei Alizadeh, Thomas Trautmann, Florian Krause, Benjamin Knoeferl, Pieter-Jan Guns, Guido De Meyer, Brian D. Guth, Michael Markert. The impact of environmental and biological factors on the resting heart rate of dogs as assessed using 20 years of data from safety pharmacology studiesJournal of Pharmacological and Toxicological Methods, 2023, Vol. 121, 107263. DOI: 10.1016/j.vascn.2023.107263Open Access

Patrizia Pannucci, Sophie R. Jefferson, Jonathan Hampshire, Samantha L. Cooper, Stephen J. Hill, and Jeanette Woolard. COVID-19-Induced Myocarditis: Pathophysiological Roles of ACE2 and Toll-like Receptors. International Journal Molecular Science 2023, 24(6), 5374. DOI: 10.3390/ijms24065374. Open Access

2022

Edward S. Wragg, Patrizia Pannucci, Stephen J. Hill, Jeanette Woolard, Samantha L. Cooper. Involvement of β- adrenoceptors in the cardiovascular responses induced by selective adenosine A2A and A2B receptor agonistsPharmacology Research & Perspectives, Vol.10, Issue3. June 2022. DOI: 10.1002/prp2.975. Open Access

Haibo Liu, Tessa De Korte, Sylvain Bernasconi, Christophe Bleunven, Damiano Lombardi, Muriel Boulakia. Artificial Neural Network Comparison on hERG Channel Blockade Detection. International Journal Of Computer Applications. Volume 184 - No.14, May 2022. DOI: 10.5120/ijca2022922119. Open Access

Marieke Van Daele, Samantha L Cooper, Patrizia Pannucci, Edward S Wragg, Julie March, Iwan de Jong and Jeanette Woolard. Monitoring haemodynamic changes in rodent models to better inform safety pharmacology: Novel insights from in vivo studies and waveform analysis. JRSM Cardiovascular Disease, Vol. 11: 1–9. May 2022. DOI: 10.1177/20480040221092893. Open Access

Christian J. M. I. Klein, Thomas Budiman, Judith R. Homberg, Dilip Verma, Jaap Keijer and Evert M. van Schothorst. Measuring Locomotor Activity and Behavioral Aspects of Rodents Living in the Home-Cage. Frontiers Behavioral Neuroscience, Vol. 16, April 2022. DOI: 10.3389/fnbeh.2022.877323. Open Access

Samantha L. Cooper, Edward S. Wragg, Patrizia Pannucci, Mark Soave, Stephen J. Hill, Jeanette Woolard. Regionally selective cardiovascular responses to adenosine A2A and A2B receptor activation. The FASEB Journal. Vol. 36, Issue 4 April 2022. DOI: 10.1096/fj.202101945ROpen Access

2021

Matthias Bosman, Dustin N. Krüger, Kasper Favere, Callan D. Wesley, Cédric H. G. Neutel, Birgit Van Asbroeck, Owen R. Diebels, Bart Faes,Timen J. Schenk, Wim Martinet, Guido R. Y. De Meyer, Emeline M. Van Craenenbroeck and Pieter-Jan D. F. Guns. Doxorubicin Impairs Smooth Muscle Cell Contraction: Novel Insights in Vascular Toxicity. International Journal Molecular Science 2021, 22(23), 12812  DOI: 10.3390/ijms222312812Open Access

2020

Muriel Boulakia, Haibo Liu, Damiano Lombardi. Parameter identification through gradient flow on latent variablesHal Open Science. version 1, 26 December 2023. HAL Id: hal-02966758Open Access

PJ. D.Guns, B.D.Guth, S. Braam, G. Kosmidis, E. Matsa, A. Delaunois, V. Gryshkova, S. Bernasconi, H. Knot, Yair Sh., A. Chen, M. Markert, M. Fernandez, D. Lombardi, C. Grandmont, B. Cillero-Pastor, R. M.A. Heeren, W. Martinet, J. Woolard, M. Skinnerk, V. F.M. Segers, C. Franssen, E. M. Van Craenenbroeck, P. G.A.Volders, Th. Pauwelyn, D. Braeken, P. Yanez, K. Correll, X. Yang, H. Prior, G. Kismihókt, G. R.Y. De Meyer, JP. Valentin (2020) INSPIRE: A European training network to foster research and training in cardiovascular safety pharmacology, Journal of Pharmacological and Toxicological Methods. Volume 105, September 2020, 106889. DOI 10.1016/j.vascn.2020.106889. Open Access