This CAPRI research line mainly focuses on the neurobiological, psychophysiological and psychological vulnerability and correlates of the comorbidity and interactions between affective disorders and somatic pathology or functional syndromes, as well as on the diagnostic and therapeutic implications.

We have examined the clinical impact of childhood trauma and mental health in adulthood in longitudinal designs. Furthermore, we have investigated posttraumatic stress disorder (PTSD) following civilian traumatic brain injury. In the ongoing PhD projects, we examine the predictive value of personality characteristics and symptom-based subgroups in CFS on the short and long term outcomes of group cognitive behaviour therapy. We also perform research on the neurobiology of the heterogeneity of panic disorder. Finally, a research line focuses on the presence and effects of certain emotion regulation strategies (e.g. experiential avoidance, dampening, rumination) on the present and persistence of psychiatric symptomatology.