Publications - LMM

​Host immunological responses facilitate development of SARS-CoV-2 mutations in patients receiving monoclonal antibody treatments​

Gupta A., Konnova A., Smet M., Berkell M., Savoldi A., Morra M., Van averbeke V., De Winter F., Peserico D., Danese E., Hotterbeekx A., Righi E., De Nardo P., Tacconelli E., Malhotra-Kumar S. and Kumar-Singh S.

J Clin Invest. 2023. https://doi.org/10.1172/JCI166032

​Atypical Antibody Dynamics During Human Coronavirus HKU1 Infections​

Sechan F., Grobben M., W. D. Edridge A., Jebbink M., Loens K., Ieven M., Goossens H., van Hemert-Glaubitz S., van Gils M., van der Hoek L.

Front. Microbiol., April 2022, Sec. Virology, Volume 13 - 2022 | https://doi.org/10.3389/fmicb.2022.853410

This article is part of the Research Topic 'Human coronavirus research: 20 Years since the SARS-CoV outbreak'

​Genomic analysis of methicillin-resistant Staphylococcus aureus clonal complex 239 isolated from Danish patients with and without an international travel history​

Coppens J, Xavier BB, Vlaeminck J,Larsen J, Lammens C, Van Puyvelde S,Goossens H, Larsen AR and Malhotra-Kumar S 

Front. Microbiol. 13:1016829.doi: 10.3389/fmicb.2022.1016829 (2022)

​Gut to lung translocation and antibiotic mediated selection shape the dynamics of Pseudomonas aeruginosa in an ICU patient​

Wheatley R.M., Caballero J.D., van der Schalk T.E., De Winter F.H.R, Shaw L.P., Kapel N., Recanatini C., Timbermont L., Kluytmans J., Esser M., Lacoma A., Prat-Aymerich C., Oliver A., Kumar-Singh S., Malhotra-Kumar S., MacLean R.C.

Nature Communications volume 13, Article number: 6523 (2022). https://doi.org/10.1038/s41467-022-34101-2

​Screening of global microbiomes implies ecological boundaries impacting the distribution and dissemination of clinically relevant antimicrobial resistance genes​

Lin, Q., Xavier, B.B., Alako B.T.F., Mitchell A.L., Rajakani S.G., Glupczynski Y., Finn R.D., Cochrane G., Malhotra-Kumar S.

Communications Biology volume 5, Article number: 1217 (2022)

Methodological Guidance for Clinical Metagenomics and Antimicrobial Resistance Research​

De Koster S., Rodriguez-Ruiz J. P., Glupczynski Y., Goossens H., Xavier B. B.

Microb Health Dis 2022; 4 (3): e773, DOI: 10.26355/mhd_20229_773

​Host immunological responses facilitate development of SARS-CoV-2 mutations in patients receiving monoclonal antibody treatments

Gupta A., Konnova A., Smet M., Berkell M., Savoldi A., Morra M., Van averbeke V., De Winter F., Peserico D., Danese E., Hotterbeekx A., Righi E., mAb ORCHESTRA working group, De Nardo P., Tacconelli E., Malhotra Kumar S., Kumar Singh S.

medRxiv 2022.09.20.22280135; doi: (2022)

Convergence of virulence and antimicrobial resistance in increasingly prevalent Escherichia coli ST131 papGII+ sublineages​

Biggel Michael, Moons Pieter, Nguyen Minh Ngoc, Goossens Herman & Van Puyvelde Sandra 

Communications Biology 5, 752 (2022)

​Genetic and Structural Variation in the O-Antigen of Salmonella enterica Serovar Typhimurium Isolates Causing Bloodstream Infections in the Democratic Republic of the Congo​

Van Puyvelde S, Gasperini G, Biggel M, Phoba MF, Raso MM, de Block T, Vanheer LN, Deborggraeve S, Vandenberg O, Thomson N, Ravenscroft N, Maclennan CA, Bellich B, Cescutti P, Dougan G, Jacobs J, Lunguya O, Micoli F. 

mBio - eISSN2150-7511 - e00374-22 - doi: 10.1128 (2022)

​Diversity in the characteristics of Klebsiella pneumoniae ST101 of Human, environmental, and animal origin

De Koster Sien, Rodriguez Ruiz Juan Pablo, Rajakani Sahaya Glingston, Lammens Christine, Glupczynski Youri, Goossens Herman, Xavier Britto Basil

Frontiers in microbiology - ISSN 1664-302X - 13(2022), 838207

Assessing the impact of flavophospholipol and virginiamycin supplementation on the broiler microbiota : a prospective controlled intervention study

Ahmed Mohamed Mysara, Berkell Matilda, Xavier Britto Basil, De Backer Sarah, Lammens Christine, Hautekiet Veerle, Petkov Spas, Goossens Herman, Kumar-Singh Samir, Malhotra Surbhi

mSystems - ISSN 2379-5077 - 6:4(2021), e00381-21

​Assessing the impact of the Global Point Prevalence Survey of Antimicrobial Consumption and Resistance (Global-PPS) on hospital antimicrobial stewardship programmes : results of a worldwide survey

Pauwels Ines, Versporten Ann, Vermeulen Helene, Vlieghe Erika, Goossens Herman

Antimicrobial resistance & infection control - ISSN 2047-2994 - 10:1(2021), 138

​COMBACTE LAB-Net : building a European laboratory network for clinical trials on anti-infectives

Kostyanev Tomislav, Timbermont Leen, Vilken Tuba, Lammens Christine, Malhotra Surbhi, Glupczynski Youri, Goossens Herman

Future microbiology - ISSN 1746-0913 - London, Future medicine ltd, 16:9(2021), p. 635-647

​Consumption of cephalosporins in the community, European Union/European Economic Area, 1997–2017

Versporten Ann, Bruyndonckx Robin, Adriaenssens Niels, Hens Niel, Monnet Dominique L., Molenberghs Geert, Goossens Herman, Weist Klaus, Coenen Samuel, Strauss Reinhild, Vandael Eline, Sabtcheva Stefana, Payerl-Pal Marina, Kyriakidou Isavella, Vlček Jiří, Sönksen Ute Wolff, Linask Elviira, Sarvikivi Emmi, Hider-Mlynarz Karima, Dollen Katja Niepraschk-von, ...

The journal of antimicrobial chemotherapy - ISSN 0305-7453 - 76:S2(2021), p. 22-29

​Consumption of tetracyclines, sulphonamides and trimethoprim, and other antibacterials in the community, European Union/European Economic Area, 1997–2017

Versporten Ann, Bruyndonckx Robin, Adriaenssens Niels, Hens Niel, Monnet Dominique L., Molenberghs Geert, Goossens Herman, Weist Klaus, Coenen Samuel, Strauss Reinhild, Vandael Eline, Sabtcheva Stefana, Andrašević Arjana Tambić, Kyriakidou Isavella, Vlček Jiří, Sönksen Ute Wolff, Linask Elviira, Sarvikivi Emmi, Hider-Mlynarz Karima, Blank Hans-Peter, ...

The journal of antimicrobial chemotherapy - ISSN 0305-7453 - 76:S2(2021), p. 45-59

​Diagnostic performance of the IdyllaTM respiratory panel for molecular detection of influenza A/B in patients presenting to primary care with influenza-like illness during 3 consecutive influenza seasons

Matheeussen Veerle, Loens Katherine, Kuijstermans Mandy, Jacobs Kevin, Coenen Samuel, van der Velden Alike W., Bongard Emily, Butler Chris C., Verheij Theo J.M., Goossens Herman, Ieven Margaretha

Journal of clinical virology - ISSN 1386-6532 - 144(2021), 104998

​ESBL-producing, carbapenem- and ciprofloxacin-resistant Escherichia coli in Belgian and Dutch broiler and pig farms : a cross-sectional and cross-border study

De Koster Sien, Ringenier Moniek, Lammens Christine, Stegeman Arjan, Tobias Tijs, Velkers Francisca, Vernooij Hans, Kluytmans-van den Bergh Marjolein, Kluytmans Jan, Dewulf Jeroen, Goossens Herman

Antibiotics - ISSN 2079-6382 - 10:8(2021), 945

​Evaluation of GeneXpert PA assay compared to genomic and (semi-)quantitative culture methods for direct detection of Pseudomonas aeruginosa in endotracheal aspirates

van der Schalk Thomas, Coppens Jasmine, Timbermont Leen, Turlej-Rogacka Agata, van Heirstraeten Liesbet, Berkell Matilda, Yu Li, Lammens Christine, Xavier Britto Basil, Matheeussen Veerle, Ieven Margaretha, McCarthy Michael, Jorens Philippe, Ruzin Alexey, Esser Mark T., Kumar-Singh Samir, Goossens Herman, Malhotra Surbhi

Antimicrobial resistance & infection control - ISSN 2047-2994 - 10:1(2021), 110

​Following the science? Views from scientists on government advisory boards during the COVID-19 pandemic: a qualitative interview study in five European countries

Colman Elien, Wanat Marta, Goossens Herman, Tonkin-Crine Sarah, Anthierens Sibyl

BMJ Global Health - ISSN 2059-7908 - 6:9(2021), e006928

​Helicobacter pylori resistance to antibiotics in Europe in 2018 and its relationship to antibiotic consumption in the community

Megraud Francis, Bruyndonckx Robin, Coenen Samuel, Wittkop Linda, Huang Te-Din, Hoebeke Martin, Benejat Lucie, Lehours Philippe, Goossens Herman, Glupczynski Youri

Gut : the journal of the British Society for Gastroenterology / British Society for Gastroenterology - ISSN 1468-3288 - 70:10(2021), p. 1815-1822

​Hospital antibiotic prescribing patterns in adult patients according to the WHO Access, Watch and Reserve classification (AWaRe) : results from a worldwide point prevalence survey in 69 countries

Pauwels Ines, Versporten Ann, Drapier Nico, Vlieghe Erika, Goossens Herman, Koraqi Andi, Hoxha Iris, Tafaj Silva, Cornistein Wanda, Quiros Rodolfo, Hojman Martin, Ghazaryan Lilit, Horne Kylie, Cairns Kelly, Doukas Fiona, Gottlieb Thomas, Sermijn Erica, Verhamme Katia, Brands Christiane, Van Herendael Bruno, ...

The journal of antimicrobial chemotherapy - ISSN 0305-7453 - 76:6(2021), p. 1614-1624

​Microbiota-based markers predictive of development of Clostridioides difficile infection

Berkell Matilda, Mysara Mohamed, Xavier Britto Basil, van Werkhoven Cornelis H., Monsieurs Pieter, Lammens Christine, Ducher Annie, Vehreschild Maria J.G.T., Goossens Herman, de Gunzburg Jean, Bonten Marc J. M., Malhotra Surbhi, Ahmed Mohamed Mysara, Engbers Annemarie, de Regt Marieke, Biehl Lena M., Cornely Oliver A., Jazmati Nathalie, Bouverne Marie-Noelle, Sablier-Gallis Frederique, ...

Nature communications - ISSN 2041-1723 - 12:1(2021), 2241

​Novel vancomycin resistance gene cluster in Enterococcus faecium ST1486, Belgium, June 2021

Xavier Britto Basil, Coppens Jasmine, De Koster Sien, Rajakani Sahaya Glingston, Van Goethem Sam, Mzougui Samy, Anantharajah Ahalieyah, Lammens Christine, Loens Katherine, Glupczynski Youri, Goossens Herman, Matheeussen Veerle

Eurosurveillance: European communicable disease bulletin / European Communities. Commission; Communautés européennes. Commission - ISSN 1560-7917 - 26:36(2021), 2100767

​Phenotypic and molecular characterizations of carbapenem-resistant Acinetobacter baumannii isolates collected within the EURECA study

Kostyanev Tomislav, Xavier Britto Basil, Garcia-Castillo M., Lammens Christine, Bravo-Ferrer Acosta J., Rodriguez-Bano J., Canton R., Glupczynski Y., Goossens Herman

International journal of antimicrobial agents - ISSN 0924-8579 - 57:6(2021), 106345

​Prevalence of antibiotic-resistant bacteria among patients in two tertiary hospitals in Eastern Uganda

Obakiro Samuel Baker, Kiyimba Kenedy, Paasi George, Napyo Agnes, Anthierens Sibyl, Waako Paul, Van Royen Paul, Iramiot Jacob Stanley, Goossens Herman, Kostyanev Tomislav

Journal of Global Antimicrobial Resistance - ISSN 2213-7165 - 25(2021), p. 82-86

​Prospective One Health genetic surveillance in Vietnam identifies distinct blaCTX-M-harbouring Escherichia coli in food-chain and human-derived samples

Nguyen Ngoc Minh, Thu Hoang Ha Thi, Xavier Britto Basil, Lammens Christine, Le Hai Thanh, Bich Hoang Ngoc Thi, Nguyen Son Thai, Pham Ngoc Thi, Goossens Herman, Dang Anh Duc, Malhotra Surbhi

Clinical microbiology and infection / European Society of Clinical Microbiology and Infectious Diseases; ESCMID - ISSN 1469-0691 - 27:10(2021), p. 1515.e1-1515.e8

Antibiotic use and resistance in Belgium: the impact of two decades of multi-faceted campaigning

Bruyndonckx Robin, Coenen Samuel, Hens Niel, Vandael E., Catry B., Goossens Herman

Acta clinica Belgica / Belgian Society of Internal Medicine [Ghent]; Royal Belgian Society of Laboratory Medicine - ISSN 1784-3286 - Abingdon, Taylor & francis ltd, 2020, 9 p.

​BacPipe : a rapid, user-friendly whole-genome sequencing pipeline for clinical diagnostic bacteriology

Xavier Britto Basil, Ahmed Mohamed Mysara, Bolzan Mattia, Ribeiro-Gonçalves Bruno, Alako Blaise T.F., Harrison Peter, Lammens Christine, Kumar-Singh Samir, Goossens Herman, Carriço João A., Cochrane Guy, Malhotra Surbhi

iScience - ISSN 2589-0042 - 23:1(2020), 100769

​Emergence of ST654 Pseudomonas aeruginosa co-harbouring bla(NDM-1) and bla(GES-5) in novel class I integron In 1884 from Bulgaria

Kostyanev Tomislav, Nguyen M. N., Markovska R., Stankova P., Xavier Britto Basil, Lammens Christine, Marteva-Proevska Y., Velinov T., Canton R., Goossens Herman, Malhotra Surbhi

Journal of Global Antimicrobial Resistance - ISSN 2213-7165 - 22(2020), p. 672-673

​Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages

Biggel Michael, Xavier Britto Basil, Johnson James R., Nielsen Karen L., Frimodt-Moller Niels, Matheeussen Veerle, Goossens Herman, Moons Pieter, Van Puyvelde Sandra

Nature communications - ISSN 2041-1723 - 11:1(2020), 5968

​How nasopharyngeal pneumococcal carriage evolved during and after a PCV13-to-PCV10 vaccination programme switch in Belgium, 2016 to 2018

Wouters Ine, Desmet Stefanie, van Heirstraeten Liesbet, Herzog Sereina, Beutels Philippe, Verhaegen Jan, Goossens Herman, van Damme Pierre, Malhotra Surbhi, Theeten Heidi, van Damme Pierre, Tuerlinckx David, Finn Adam, van Herck Koen, Cohen Robert, Lammens Christine

EuroSurveillance Monthly - ISSN 1560-7917 - 25:5(2020), 1900303

​International external quality assessment for SARS-CoV-2 molecular detection and survey on clinical laboratory preparedness during the COVID-19 pandemic, April/May 2020

Matheeussen Veerle, Corman Victor M., Mantke Oliver Donoso, McCulloch Elaine, Lammens Christine, Goossens Herman, Niemeyer Daniela, Wallace Paul S., Klapper Paul, Niesters Hubert G. M., Drosten Christian, Ieven Margaretha

EuroSurveillance Monthly - ISSN 1560-7917 - 25:27(2020), 2001223

​Preparedness of European diagnostic microbiology labs for detection of SARS-CoV-2, March 2020

Matheeussen Veerle, Loens Katherine, Lammens Christine, Vilken Tuba, Koopmans Marion, Goossens Herman, Ieven Margaretha

Journal of clinical virology - ISSN 1386-6532 - 128(2020)5 p.

​Respiratory syncytial virus and influenza virus infection in adult primary care patients : association of age with prevalence, diagnostic features and illness course

Bruyndonckx Robin, Coenen Samuel, Butler Chris, Verheij Theo, Little Paul, Hens Niel, Beutels Philippe, Ieven Margaretha, Goossens Herman

International journal of infectious diseases / International Society for Infectious Diseases; ISID - ISSN 1201-9712 - 95(2020), p. 384-390

​Antibiotic prescribing for acute respiratory tract infections 12 months after communication and CRP training : a randomized trial

Little Paul, Stuart Beth, Francis Nick, Anthierens Sibyl, Coenen Samuel, Goossens Herman, et al.

Annals of Family Medicine online - ISSN 1544-1709 - 17:2(2019), p. 125-132

​Comparison of GeneXpert MRSA/SA ETA assay with semi-quantitative and quantitative cultures and nuc gene-based qPCR for detection of Staphylococcus aureus in endotracheal aspirate samples

Coppens Jasmine, van Heirstraeten Liesbet, Ruzin Alexey, Yu Li, Timbermont Leen, Lammens Christine, Matheeussen Veerle, McCarthy Michael, Jorens Philippe, Ieven Margaretha, Kumar-Singh Samir, Goossens Herman, Malhotra Surbhi

Antimicrobial resistance & infection control - ISSN 2047-2994 - 8(2019), 4

​Detection and prevalence of carbapenem-resistant Gram-negative bacteria among European laboratories in the COMBACTE network : a COMBACTE LAB-Net survey

Kostyanev Tomislav, Vilken Tuba, Lammens Christine, Timbermont Leen, Van't Veen A., Goossens Herman

International journal of antimicrobial agents - ISSN 0924-8579 - 53:3(2019), p. 268-274

​Emergence of colistin resistance during treatment of recurrent pneumonia caused by carbapenemase producing Klebsiella pneumoniae

Matheeussen Veerle, Xavier Britto Basil, Mermans Ingrid, De Weerdt Annick, Lammens Christine, Goossens Herman, Jansens Hilde, Malhotra Surbhi

Diagnostic microbiology and infectious disease - ISSN 0732-8893 - 94:4(2019), p. 407-409

​Follow-up of serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae in child carriage after a PCV13-to-PCV10 vaccine switch in Belgium

Wouters Ine, Desmet Stefanie, van Heirstraeten Liesbet, Blaizot Stéphanie, Verhaegen Jan, van Damme Pierre, Malhotra Surbhi, Theeten Heidi, De Wilde Barbara, De Meulemeester Marc, Azou Myriam, Verghote Marc, Tuerlinckx David, Verlinden Raf, Cohen Robert, Finn Adam, Van Herck Koen, Goossens Herman

Vaccine / International Society for Vaccines - ISSN 0264-410X - 37:8(2019), p. 1080-1086

​Potential in vivo transfer of a plasmid established by combining long- and short-read sequencing

Xavier Britto Basil, Renzi Gesuele, Lammens Christine, Cherkaoui Abdessalam, Goossens Herman, Schrenzel Jacques, Harbarth Stephan, Malhotra Surbhi

Journal of microbiological methods - ISSN 0167-7012 - 159(2019), p. 1-4

​Quality of molecular detection of vancomycin resistance in enterococci : results of 6 consecutive years of Quality Control for Molecular Diagnostics (QCMD) external quality assessment

Matheeussen Veerle, Loens Katherine, Scott Calum, Di Lorenzo Caterina, McCulloch Elaine, Mantke Oliver Donoso, Goossens Herman, Wallace Paul, Ieven Margaretha

European journal of clinical microbiology and infectious diseases / European Society for Clinical Microbiology and Infectuous Diseases - ISSN 0934-9723 - 38:9(2019), p. 1633-1641

​Remarkable genome stability among emm1 group A streptococcus in Belgium over 19 years

Coppens Jasmine, Xavier Britto Basil, Loens Katherine, Lammens Christine, Ieven Margaretha, Matheeussen Veerle, Goossens Herman, Malhotra Surbhi

Genome Biology and Evolution - ISSN 1759-6653 - 11:5(2019), p. 1432-1439

​Remarkable geographical variations between India and Europe in carriage of the staphylococcal surface protein-encoding sasX/sesI and in the population structure of methicillin-resistant Staphylococcus aureus belonging to clonal complex 8

De Backer Sarah, Xavier Britto Basil, Vanjari L., Coppens J., Lammens Christine, Vemu L., Carevic B., Hryniewicz W., Jorens Philippe, Kumar-Singh Samir, Lee A., Harbarth S., Schrenzel J., Tacconelli E., Goossens Herman, Malhotra Surbhi

Clinical microbiology and infection / European Society of Clinical Microbiology and Infectious Diseases; ESCMID - ISSN 1198-743X - 25:5(2019)7 p.

​Variations in antibiotic use across India : multi-centre study through Global Point Prevalence survey

Singh S. K., Sengupta S., Antony R., Bhattacharya S., Mukhopadhyay C., Ramasubramanian V., Sharma A., Sahu S., Nirkhiwale S., Gupta S., Rohit A., Sharma S., Raghavan V., Barman P., Sood S., Mamtora D., Rengaswamy S., Arora A., Goossens Herman, Versporten Ann

The journal of hospital infection - ISSN 0195-6701 - 103:3(2019), p. 280-283

​Aetiology of lower respiratory tract infection in adults in primary care : a prospective study in 11 European countries

Ieven Margaretha, Coenen Samuel, Loens Katherine, Lammens Christine, Coenjaerts E., Vanderstraeten Anouk, Henriques-Normark B., Crook D., Huygen K., Butler C. C., Verheij T. J. M., Little P., Zlateva K., van Loon A., Claas E. C. J., Goossens Herman

Clinical microbiology and infection / European Society of Clinical Microbiology and Infectious Diseases; ESCMID - ISSN 1198-743X - 24:11(2018), p. 1158-1163

​Analytical performance of a platform for point-of-care CRP testing in adults consulting for lower respiratory tract infection in primary care

Matheeussen Veerle, Van Hoof Viviane, Loens Katherine, Lammens Christine, Vanderstraeten Anouk, Coenen Samuel, Butler Chris C., Little Paul, Verheij Theo J.M., Goossens Herman, Ieven Margaretha

European journal of clinical microbiology and infectious diseases / European Society for Clinical Microbiology and Infectuous Diseases - ISSN 0934-9723 - 37:7(2018), p. 1319-1323

​Antimicrobial consumption and resistance in adult hospital inpatients in 53 countries : results of an internet-based global point prevalence survey

Versporten Ann, Zarb Peter, Caniaux Isabelle, Gros Marie-Francoise, Drapier Nico, Miller Mark, Jarlier Vincent, Nathwani Dilip, Goossens Herman

The Lancet Global Health - ISSN 2214-109X - 6:6(2018), p. E619-E629

​Discovery, research, and development of new antibiotics : the WHO priority list of antibiotic-resistant bacteria and tuberculosis

Tacconelli Evelina, Carrara Elena, Savoldi Alessia, Goossens Herman, Malhotra Surbhi, et al.

The lancet infectious diseases - ISSN 1473-3099 - 18:3(2018), p. 318-327

​Enzymes catalyzing the TCA- and urea cycle influence the matrix composition of biofilms formed by methicillin-resistant staphylococcus aureus USA300

De Backer Sarah, Sabirova Julia, De Pauw Ines, De Greve Henri, Hernalsteens Jean-Pierre, Goossens Herman, Malhotra Surbhi

Microorganisms - ISSN 2076-2607 - 6:4(2018), 113

​Evaluation of colistin stability in agar and comparison of four methods for MIC testing of colistin

Turlej-Rogacka Agata, Xavier Britto Basil, Janssens Lore, Lammens Christine, Zarkotou Olympia, Pournaras Spyros, Goossens Herman, Malhotra Surbhi

European journal of clinical microbiology and infectious diseases / European Society for Clinical Microbiology and Infectuous Diseases - ISSN 0934-9723 - 37:2(2018), p. 345-353

​Metrics to assess the quantity of antibiotic use in the outpatient setting : a systematic review followed by an international multidisciplinary consensus procedure

Versporten Ann, Gyssens Inge C., Pulcini Celine, Monnier Annelie A., Schouten Jeroen, Milanic Romina, Benic Mirjana Stanic, Tebano Gianpiero, Le Marechal Marion, Zanichelli Veronica, Huttner Benedikt, Vlahovic-Palcevski Vera, Goossens Herman, Hulscher Marlies E., Adriaenssens Niels

The journal of antimicrobial chemotherapy - ISSN 0305-7453 - Oxford, Oxford univ press, 73:s:[6](2018), p. 59-66

​Surveillance for control of antimicrobial resistance

Tacconelli Evelina, Sifakis Frangiscos, Harbarth Stephan, Schrijver Remco, van Mourik Maaike, Voss Andreas, Sharland Mike, Rajendran Nithya Babu, Rodríguez-Baño Jesús, Goossens Herman, Malhotra Surbhi, et. al

The lancet infectious diseases - ISSN 1473-3099 - 18:3(2018), p. e99-e106

​Emergence of antimicrobial resistance to Pseudomonas aeruginosa in the intensive care unit: association with the duration of antibiotic exposure and mode of administration

Yusuf Erlangga, Van Herendael Bruno, Verbrugghe Walter, Ieven Margaretha, Goovaerts Emiel, Bergs Kristof, Wouters Kristien, Jorens Philippe, Goossens Herman

Annals of intensive care / Société de réanimation de langue française - ISSN 2110-5820 - 7(2017), 72

​In vivo and In vitro Interactions between Pseudomonas aeruginosa and Staphylococcus spp.

Hotterbeekx An, Kumar-Singh Samir, Goossens Herman, Malhotra Surbhi

Frontiers in cellular and infection microbiology / Informatics (India) Pvt. Ltd - ISSN 2235-2988 - Lausanne, Frontiers media sa, 7(2017), 106

​Is there any difference in quality of prescribing between antibacterials and antifungals? Results from the first global point prevalence study (Global PPS) of antimicrobial consumption and resistance from 53 countries

Yusuf Erlangga, Versporten Ann, Goossens Herman

The journal of antimicrobial chemotherapy - ISSN 0305-7453 - 72:10(2017), p. 2906-2909

​Impact of amoxicillin therapy on resistance selection in patients with community-acquired lower respiratory tract infections : a randomized, placebo-controlled study​

Malhotra Surbhi, van Heirstraeten Liesbet, Coenen Samuel, Lammens Christine, Adriaenssens Niels, Kowalczyk Anna, Godycki-Cwirko Maciek, Bielicka Zuzana, Hupkova Helena, Lannering Christina, Molstad Sigvard, Fernandez-Vandellos Patricia, Torres Antoni, Parizel, Ieven Margaretha, Butler Chris C., Verheij Theo, Little Paul, Goossens Herman

The journal of antimicrobial chemotherapy - ISSN 0305-7453 - 71:11(2016), p. 3258-3267

​Public funding for research on antibacterial resistance in the JPIAMR countries, the European Commission, and related European Union agencies : a systematic observational analysis

Kelly Ruth, Zoubiane Ghada, Walsh Desmond, Ward Rebecca, Goossens Herman

The lancet infectious diseases - ISSN 1473-3099 - 16:4(2016), p. 431-440

​The innovative medicines initiative's new drugs for bad bugs programme : European public-private partnerships for the development of new strategies to tackle antibiotic resistance

Kostyanev Tomislav, Bonten M. J. M., O'Brien S., Steel H., Ross S., Francois B., Tacconelli E., Winterhalter M., Stavenger R. A., Karlen A., Harbarth S., Hackett J., Jafri H. S., Vuong C., MacGowan A., Witschi A., Angyalosi G., Elborn J. S., dewinter R., Goossens Herman

The journal of antimicrobial chemotherapy - ISSN 0305-7453 - Oxford, Oxford univ press, 71:2(2016), p. 290-295

​Whole-genome typing and characterization of -harbouring ST383 Klebsiella pneumoniae by PFGE, whole-genome mapping and WGS

Sabirova Julia, Xavier Britto Basil, Coppens Jasmine, Zarkotou Olympia, Lammens Christine, Janssens Lore, Burggrave Ronald, Wagner Trevor, Goossens Herman, Malhotra Surbhi

The journal of antimicrobial chemotherapy - ISSN 0305-7453 - (2016), p. 1-9

The endotracheal tube microbiome associated with Pseudomonas aeruginosa or Staphylococcus epidermidis

Hotterbeekx An, Xavier Britto Basil, Bielen Kenny, Lammens Christine, Moons Pieter, Schepens Tom, Ieven Margaretha, Jorens Philippe, Goossens Herman, Kumar-Singh Samir, Malhotra Surbhi

Scientific reports - ISSN 2045-2322 - 6(2016), 36507

​The Worldwide Antibiotic Resistance and Prescribing in European Children (ARPEC) point prevalence survey : developing hospital-quality indicators of antibiotic prescribing for children

Versporten Ann, Bielicki Julia, Drapier Nico, Sharland Mike, Goossens Herman, Mahieu Ludo

The journal of antimicrobial chemotherapy - ISSN 0305-7453 - 71:4(2016), p. 1106-1117

​Medical costs of treatment and survival of patients with acute myeloid leukemia in Belgium

Van de Velde Ann, Beutels Philippe, Smits Evelien, Van Tendeloo Vigor, Nijs Griet, Anguille Sébastien, Verlinden A., Gadisseur Alain, Schroyens Wilfried, Dom S., Cornille I., Goossens Herman, Berneman Zwi Nisan

Leukemia research - ISSN 0145-2126 - 46(2016), p. 26-29

​Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016

Xavier Britto Basil, Lammens Christine, Ruhal R., Kumar-Singh Samir, Butaye P., Goossens Herman, Malhotra Surbhi

EuroSurveillance Monthly - ISSN 1560-7917 - 21:27(2016), 30280

​Consolidating and exploring antibiotic resistance gene data resources

Xavier Britto Basil, Das Anupam, Cochrane Guy, De Ganck Sandra, Kumar-Singh Samir, Aerestrup Frank Møller, Goossens Herman, Malhotra Surbhi

Journal of clinical microbiology - ISSN 0095-1137 - Washington, Amer soc microbiology, 54:4(2016), p. 851-859

​3D culture of murine neural stem cells on decellularized mouse brain sections​

De Waele Jorrit, Reekmans Kristien, Daans Jasmijn, Goossens Herman,Berneman Zwi Nisan, Ponsaerts Peter

Biomaterials-issn 0142-9612-41(2015),p. 122-131

​Assessing the risk of measles resurgence in a highly vaccinated population : Belgium anno 2013​

Hens Niel, Abrams S., Santermans E., Theeten Heidi, Goeyvaerts , Lernout Tinne,Leuridan Elke, Van Kerckhove Kim, Goossens Herman, van Damme Pierre,Beutels Philippe

EuroSurveillance Monthly-issn 1560-7917-20(2015)

Culturing of respiratory viruses in well-differentiated pseudostratified human airway epithelium as a tool to detect unknown viruses 

Jazaeri Farsani Seyed Mohammad, Deijs Martin, Dijkman Ronald, Molenkamp Richard, Jeeninga Rienk E., Ieven Margaretha, Goossens Herman, van der Hoek Lia

Influenza and other respiratory viruses-issn 1750-2640-9(2015),p. 51-57

​Induction of cytomegalovirus-specific T cell responses in healthy volunteers and allogeneic stem cell recipients using vaccination with messenger RNAtransfected dendritic cells​

Van Craenenbroeck Amaryllis, Smits Evelien, Anguille Sébastien, van de Velde Ann,Stein Barbara, Braeckman Tessa, Van Camp Kirsten, Nijs Griet, Ieven Margaretha,Goossens Herman, Berneman Zwi Nisan, van Tendeloo Vigor, Verpooten Gert A., van Damme Pierre, Cools Nathalie

Transplantation-issn 0041-1337-99(2015),p. 120-127

​Survey of metallo-$eta$-lactamase-producing Enterobacteriaceae 6 colonizing patients in European ICUs and rehabilitation units, 2008-2011​

Papagiannitsis C.C., Izdebski R., Baraniak A., Goossens Herman, et al. 

The journal of antimicrobial chemotherapy-issn 0305-7453-(2015),p. 1-19

​The Belgian policy of funding antimicrobial stewardship in hospitals and trends of selected quality indicators for antimicrobial use, 19992010 : a longitudinal study​

Lambert Marie-Laure, Bruyndonckx Robin, Goossens Herman, Hens Niel, Aerts Marc, Catry Boudewijn, Neely Fiona, Vogelaers Dirk, Hammami Naima

BMJ open-issn 2044-6055-5(2015),p. 1-8

A multinational study of colonization with extended spectrum $eta$-lactamase-producing **Enterobacteriaceae** in healthcare personnel and family members of carrier patients hospitalized in rehabilitation centres 

Adler A., Baraniak A., Izdebski R., Lammens Christine, Malhotra Surbhi, Goossens Herman, et al.  

Clinical microbiology and infection-issn 1198-743X-20(2014),p. O516-O523

A systematic review and meta-analysis of the effects of antibiotic consumption on antibiotic resistance 

Bell Brian G., Schellevis Francois, Stobberingh Ellen, Goossens Herman, Pringle Mike. 

BMC infectious diseases-issn 1471-2334-14(2014),p. 1-25

​Amoxicillin for acute lower respiratory tract infection in primary care : subgroup analysis of potential high-risk groups 

Moore Michael, Stuart Beth, Coenen Samuel, Butler Chris C., Goossens Herman, Verheij Theo J.M., Little Paul. 

The British journal of general practice-issn 0960-1643-64(2014),p. 75-80

​Antibiotic use in eastern Europe : a cross-national database study in coordination with the WHO Regional Office for Europe 

Versporten Ann, Bolokhovets Ganna, Ghazaryan Lilit, Goossens Herman, et al. 

The lancet infectious diseases-issn 1473-3099-14(2014),p. 381-387

​Appropriate international measures for outpatient antibiotic prescribing and consumption: recommendations from a national data comparison of different measures 

Coenen Samuel, Gielen Birgit, Blommaert Adriaan, Beutels Philippe, Hens Niel,Goossens Herman. 

The journal of antimicrobial chemotherapy-issn 0305-7453-69(2014),p. 529-534

​Circulating dendritic cells of multiple sclerosis patients are proinflammatory and their frequency is correlated with MS-associated genetic risk factors 

Thewissen Kristof, Nuyts Amber, Deckx Nathalie, Nagels Guy, Willekens Barbara,Cras Patrick, Goossens Herman, van Tendeloo Vigor, Berneman Zwi Nisan,Cools Nathalie, et al. 

Multiple sclerosis: clinical and laboratory research-issn 1352-4585-20(2014),p. 548-557

​Clinical and microbiological impact of discontinuation of fluoroquinolone prophylaxis in patients with prolonged profound neutropenia 

Verlinden Anke, Jansens Hilde, Goossens Herman, van de Velde Ann,Schroyens Wilfried, Berneman Zwi Nisan, Gadisseur Alain. 

European journal of haematology-issn 0902-4441-93(2014),p. 302-308

​Comparison of biofilm formation between major clonal lineages of methicillin resistant **Staphylococcus aureus ** 

Vanhommerig Evelyn, Moons Pieter, Pirici Daniel, Lammens Christine,Hernalsteens Jean-Pierre, De Greve Henri, Kumar-Singh Samir, Goossens Herman,Malhotra Surbhi. 

PLoS ONE-issn 1932-6203-9(2014),p. 1-8

​Determinants of between-country differences in ambulatory antibiotic use and antibiotic resistance in Europe : a longitudinal observational study 

Blommaert Adriaan, Marais Christiaan, Hens Niel, Coenen Samuel, Muller Arno,Goossens Herman, Beutels Philippe. 

The journal of antimicrobial chemotherapy-issn 0305-7453-69(2014),p. 535-547

​Distinct in vitro properties of embryonic and extra-embryonic fibroblast-like cells are reflected in their in vivo behaviour following grafting in the adult mouse brain 

Costa Roberta, Bergwerf Irene, Santermans Eva, de Vocht Nathalie, Praet Jelle,Daans Jasmijn, Le Blon Debbie, Hoornaert Chloé, Reekmans Kristien,Goossens Herman, Berneman Zwi Nisan, Ponsaerts Peter, et al. 

Cell transplantation-issn 0963-6897-(2014),p. 1-31

​Distinct spatial distribution of microglia and macrophages following mesenchymal stem cell implantation in mouse brain 

Le Blon Debbie, Hoornaert Chloé, Daans Jasmijn, Santermans Eva, Hens Niel,Goossens Herman, Berneman Zwi Nisan, Ponsaerts Peter. 

Immunology and cell biology-issn 0818-9641-92(2014),p. 650-658

​Early inflammatory responses following cell grafting in the CNS trigger activation of the sub-ventricular zone : a proposed model of sequential cellular events 

Praet Jelle, Santermans Eva, Daans Jasmijn, Le Blon Debbie, Hoornaert Chloé,Goossens Herman, Hens Niel, van der Linden Anne-Marie, Berneman Zwi Nisan,Ponsaerts Peter. 

Cell transplantation-issn 0963-6897-(2014),p. 1-30

​Employing whole genome mapping for optimal de novo assembly of bacterial genomes 

Xavier Basil Britto, Sabirova Julia, Moons Pieter, Hernalsteens Jean-Pierre, de Greve Henri, Goossens Herman, Malhotra Surbhi. 

BMC research notes-issn 1756-0500-7(2014),p. 1-4

​Except for C-C chemokine receptor 7 expression, monocyte-derived dendritic cells from patients with multiple sclerosis are functionally comparable to those of healthy controls 

Nuyts Amber, Ponsaerts Peter, van Tendeloo Vigor, Lee Wai Ping, Stein Barbara,Nagels Guy, d' Hooghe Marie B., Willekens Barbara, Cras Patrick, Wouters Kristien,Goossens Herman, Berneman Zwi Nisan, Cools Nathalie. 

Cytotherapy-issn 1465-3249-16(2014),p. 1024-1030

​High rates of intestinal colonisation with fluoroquinolone-resistant ESBL-harbouring Enterobacteriaceae in hospitalised patients with antibiotic-associated diarrhoea 

Vervoort Jascha, Gazin Muriel, Kazma M., Kotlovsky T., Lammens Christine, Carmeli Y., Goossens Herman, Malhotra Surbhi. 

European journal of clinical microbiology and infectious diseases-issn 0934-9723-(2014)

​HPV vaccine stimulates cytotoxic activity of killer dendritic cells and natural killer cells against HPV-positive tumour cells 

Van den Bergh Johan, Guerti Khadija, Willemen Yannick, Lion Eva, Cools Nathalie,Goossens Herman, Vorsters Alex, van Tendeloo Vigor, Anguille Sébastien, van Damme Pierre, Smits Evelien. 

Journal of cellular and molecular medicine-issn 1582-4934-18(2014),p. 1372-1380

​IFITM3 and susceptibility to respiratory viral infections in the community 

Mills Tara C., Rautanen Anna, Elliott Katherine S., Ieven Margaretha,Goossens Herman, et al. 

The journal of infectious diseases-issn 0022-1899-209(2014),p. 1028-1031

​Integrated DNA and RNA extraction and purification on an automated microfluidic cassette from bacterial and viral pathogens causing community-acquired lower respiratory tract infections 

van Heirstraeten Liesbet, Spang Peter, Schwind Carmen, Goossens Herman,Malhotra Surbhi, et al. 

Lab on a chip-issn 1473-0197-(2014)

​Interventions to reduce colonisation and transmission of antimicrobial-resistant bacteria in intensive care units: an interrupted time series study and cluster randomised trial 

Derde Lennie P.G., Cooper Ben S., Goossens Herman, Malhotra Surbhi, et al. 

The lancet infectious diseases-issn 1473-3099-14(2014),p. 31-39

​Measuring trends of outpatient antibiotic use in Europe : jointly modelling longitudinal data in defined daily doses and packages 

Bruyndonckx Robin, Hens Niel, Aerts Marc, Goossens Herman, Molenberghs Geert,Coenen Samuel. 

The journal of antimicrobial chemotherapy-issn 0305-7453-69(2014),p. 1981-1986

​Medication use in European primary care patients with lower respiratory tract infection : an observational study 

Hamoen Marleen, Broekhuizen Berna D.L., Little Paul, Melbye Hasse,Coenen Samuel, Goossens Herman, Butler Chris C., Francis Nick A., Verheij Theo J.M.

The British journal of general practice-issn 0960-1643-64(2014),p. 81-91

​Metagenomic analysis of a sample from a patient with respiratory tract infection reveals the presence of a$gamma$-papillomavirus 

Canuti Marta, Deijs Martin, Farsani Seyed M. Jazaeri, Lammens Christine,Goossens Herman, Loens Katherine, Ieven Margaretha, et al. 

Frontiers in microbiology-issn 1664-302X-5(2014)

​MLST reveals potentially high-risk international clones of Enterobacter cloacae 

Izdebski R., Baraniak A., Herda M., Fiett J., Bonten M.J.M., Carmeli Y.,Goossens Herman, Hryniewicz W., Brun-Buisson C., Gniadkowski M.. 

The journal of antimicrobial chemotherapy-issn 0305-7453-(2014),p. 1-9

​Prolonged shedding of rhinovirus and re-infection in adults with respiratory tract illness 

Zlateva Kalina T., de Vries Jutte J.C., Coenjaerts Frank E.J., van Loon Anton M., Verheij Theo, Little Paul, Butler Christopher C., Goossens Herman,Ieven Margaretha, Claas Eric C.J. 

The European respiratory journal-issn 0903-1936-44(2014),p. 169-177

​Public beliefs on antibiotics and symptoms of respiratory tract infections among rural and urban population in Poland : a questionnaire study 

Godycki-Cwirko Maciek, Cals Jochen W.L., Francis Nick, Verheij Theo, Butler Christopher C., Goossens Herman, Zakowska Izabela, Panasiuk Lech.

PLoS ONE-issn 1932-6203-9(2014)

​Comment on : Measurement units for antibiotic consumption in outpatients 

Coenen Samuel, Bruyndonckx Robin, Hens Niel, Aerts Marc, Goossens Herman. 

The journal of antimicrobial chemotherapy-issn 0305-7453-(2014),p. 1-2

​Amoxicilline voor acute lageluchtweginfecties in de eerste lijn : subgroepanalyse van potentiële hoogrisicogroepen 

Moore M., Stuart B., Coenen Samuel, Butler C.C., Goossens Herman, Verheij T.J., Little P.

Huisarts nu: maandblad van de Wetenschappelijke Vereniging van Vlaamse Huisartsen-issn 0775-0501-43(2014),p. 75-76

​Internationale eenheden voor antibioticagebruik : vergelijking van nationale gegevens met verschillende meeteenheden 

Coenen Samuel, Gielen B., Blommaert Adriaan, Beutels Philippe, Hens Niel,Goossens Herman.

Huisarts nu: maandblad van de Wetenschappelijke Vereniging van Vlaamse Huisartsen-issn 0775-0501-43(2014),p. 77-79

​Komen opvattingen van patiënten over antibiotica overeen met beleid en percepties door artsen? Internationaal onderzoek bij eerstelijnspatiënten met acute hoest 

Coenen Samuel, Francis N., Kelly M., Nuttal J., Little P., Verheij T.J.M.,Goossens Herman, Butler C.C.

Huisarts nu: maandblad van de Wetenschappelijke Vereniging van Vlaamse Huisartsen-issn 0775-0501-43(2014),p. 72-73

​Antibiotic treatment failure in primary care 

Coenen Samuel, Goossens Herman.

British medical journal--349(2014)

​Complete genome sequences of nitrofurantoin-sensitive and -resistant **Escherichia coli** ST540 and ST2747 strains​

Xavier Basil Britto, Vervoort Jascha, Stewardson Andrew, Adriaenssens Niels,Coenen Samuel, Harbarth Stephan, Goossens Herman, Malhotra Surbhi.  

Genome announcements-issn 2169-8287-2(2014),p. 1-2

​Complete genome sequences of two prolific biofilm-forming **Staphylococcus aureus** isolates belonging to USA300 and EMRSA-15 clonal lineages 

Sabirova Julia, Xavier Basil Britto, Hernalsteens Jean-Pierre, De Greve H.,Ieven Margaretha, Goossens Herman, Malhotra Surbhi. 

Genome announcements-issn 2169-8287-2(2014),p. 1-2

​Exploring patients' views of primary care consultations with contrasting interventions for acute cough : a six-country European qualitative study​

Tonkin-Crine Sarah, Anthierens Sibyl, Francis Nick A., Coenen Samuel,Goossens Herman, et al.

NPJ primary care respiratory medicine-issn 2055-1010-24(2014),p. 1-6

Influence of lung function on course of disease and response to antibiotic therapy in adult primary care patients with acute cough : a post hoc analysis of patients enrolled in a prospective multicentre study​

van Erp Nicole, Little Paul, Stuart Beth, Coenen Samuel, Goossens Herman,Ieven Margaretha, e.a. 

NPJ primary care respiratory medicine-issn 2055-1010-24(2014),p. 1-7 

Risk factors for previously unknown meticillin-resistent Staphylococcus aureus carriage on admission to 13 surgical wards in Europe

A. Pan, A. Lee, B. Cooper, A. Chalfine, GL Daikos, S. Garilli, H. Goossens, S. Malhotra-Kumar, JA Martinez, A. Patroni, S. Harbarth; for the SURF Study group (MRSA colonization on admission to surgical wards in Eurome: identification of risk factors), in collaboration with the MOSAR-04 Study Team. 

J. Hosp Infect 83:107-13, 2013.

Spatially explicit prioritization of human antibiotics and antineoplastics in Europe

R. Oldenkamp, M. A.J. Huijbregts, A. Hollander, A. Versporten, H. Goossens, AD M.J. Ragas.

Environment International 51: 13-26, 2013.

The Chennai declaration on antimicrobial resistance in India

H. Goossens

The Lancet, 13: 105-106, 2013.

Amoxicillin for acute lower-respiratory-tract infection in primary care when pneumonia is not suspected: a 12-country, randomized, placebo-controlled trial

P. Little, B. Stuart, M. Moore, S. Coenen, C. Butler, M. Godycki-Cwirko, A. Mierzecki, S. Chlabicz, A. Torres, J. Almirall, M. Davies, T. Schaberg, S. Molstad, F. Blasi, A. De Sutter, J. Kersnik, H. Hupkova, P. Touboul, K. Hood, M. Mullee, G. O’Reily, C. Brugman, H. Goossens, T. Verheij, on behalf of the GRACE consortium.

The Lancet 13: 123-129, 2013.

Spatially explicit prioritization of human antibiotics and antineoplastics in Europe

Oldenkamp R, Huijbregts M, Hollander A, Versporten A, Goossens H, Ragas A.

Environmental International. 2013; 51: 13-26.

Antimicrobial prescribing in hospitalized adults stratified by age: Data from the ESAC Point-Prevalence Surveys

P. Zarb, B. Amadeo,  A.Muller, N. Drapier, V. Vankerckhoven, P. Davey, and H. Goossens

Drugs and aging 29 (1): 53 – 62, 2012.

Performance of Different Mono- and Multiplex Nucleic Acid Amplification Tests on a Multipathogen External Quality Assessment Panel

K. Loens, AM van Loon, F. Coenjaerts, Y. van Aarle, H. Goossens, P. Wallace, EJ Claas, M. Ieven; on behalf of the GRACE Study Group

Journal of Clinical Microbiology 50(3): 977-987, 2012.

In vitro antibacterial activity of the ceftazidime-avibactam (NXL104) combination against Pseudomonas aeruginosa clinical isolates

P. Levasseur, A. Girard,  M. Claudon1, H. Goossens, M. Black, K. Coleman, C. Miossec

Antimicrob Agents Chemother  50(3):1606-1608, 2012.

Antimicrobial Drug Use and Macrolide-resistant Streptococcus pyogenes, Belgium

L. Van Heirstraeten, S. Coenen, C. Lammens, N. Hens, H. Goossens and Surbhi Malhotra-Kumar.

Emerging Infectiouis Diseases 18(9): 1515-1518, 2012.

Human use of antimicrobial agents

P. Zarb, H. Goossens 

Rev. Sci. Techn. Off. Int. Epiz 31(1): 121-133, 2012.

Primary Care Clinicians’ Perceptions of Antibiotic Resistance: a multi-country European qualitative interview study

F. Wood, C. Phillips, L. Brookes-Howell, K. Hood, T. Verheij, S. Coenen, P. Little, H. Melbye, M. Godycki-Cwirko, K. Jakobsen, P. Worby, H. Goossens, C. Butler

Journal of Antimicrobial Chemotherapy doi:10.1093/jac/dks338, 2012

Priority actions to fight antibiotic resistance: results of an international meeting

V. Jarlier, J. Carlet, J McGowan, H. Goossens, A. Voss, S. Harbarth and D. Pittet the participants of the 3rd World healthcare-associated infections Forum.

Antimicrobial Resistance & Infection Control 1:17, 2012.

‘The Body Gets Used to Them’: Patients’ Interpretations of Antibiotic Resistance and the Implications for Containment Strategies

L. Brookes-Howell

Journal of General Internal Medicine, 27 (7): 766-772, 2012.

Severity assessment for lower respiratory tract infections: Potential use and validity of CRB-65 in primary care

NA. Francis, J. Cals, CC. Butler, K. Hood, T. Verheij, P. Little, H. Goossens, S. Coenen  on behalf of the GRACE Project Groupl

Primary Care Respiratory Journal 21:65-70, 2012.

European Position Paper on Rhinosinusitis and Nasal Polyps 2012

W. J. Fokkens, V.J. Lund, J. Mullol, C. Bachert, I. Alobid, F. Baroody, N. Cohen, A. Cervin, R. Douglas, P. Gevaert, C. Georgalas, H. Goossens, R. Harvey, P. Hellings, C. Hopkins, N. Jones, G. Joos, L. Kalogjera, B; Kern, M. Kowalski, D. Price, H. Riechelmann, R. Schlosser, B. Senior, M. Thomas, Elina Toskala, R. Voegels, D. Yun Wang, P. Wormald

Rhinology, 50 (suppl 23): 1-298, 2012.

Antibiotics for acute cough: an international observational study of patient adherence.

N. Francis, D. Gillespie, J. Nuttall, K. Hood, P. Little, T. Verheij, S. Coenen, JW. Cals, H. Goossens, CC. Butler

British Journal General Practice 62: e429-437, 2012.

The European Centre for Disease Prevention and Control (ECDC) pilot point prevalence survey of healtcare-associated infections and antimicrobial use

P. Zarb, B. Coignard, J. Griskeviciene, A. Muller, V. Vankerckhoven, K. Weist, MM Goossens, S. Vaerenberg, d. Hopkins, B. Catry, DL Monnet, H. Goossens, C. Suetens, National Contact Points for the ECDC pilot point prevalence survey, Hospital Contact Points for the ECDC pilot point prevalence survey.

Eurosurveillance, Nov., 2012.

Delayed antibiotic prescribing and associated antibiotic consumption in adults with acute cough

N. Francis, D. Gillespie, J.  Nuttall, K. Hood, P. Little, T. Verheij, H. Goossens, S. Coenen, and C. Butler

British Journal of General Practise, 62: 639-64, 2012.

A point prevalence survey of antibiotic prescriptions: benchmarking and patterns of use.

M.A. Aldeyab, M.P. Kearney, J.C. McElnay, F.A. Magee, G. Conlon, D. Gill, P. Davey, A. Muller, H. Goossens and M. G. Scott on behalf of the ESAC hospital Care Subproject Group.

Britisch Journal of Clinical Pharmacology: 71:293-296, 2011.

A sensitive assay for virus discovery in respiratory clinical samples.

M. de Vries, M. Deijs, M. Canuti, B.D.C. van Schalk, N.R. Faria, M. D.b. van de Garde, L. C.M. Jachimowski, M.F. Jebbink, M. Jakobs, A. C.M. Luyf, F. E.J. Coenjaerts, E.C.J. Claas, R. Molenekamp, S. M. Koekkoek, C. Lammens, F. Leus, H. Goossens, M. Ieven, F. Baas, L. van der Hoek.

PloSone. 6: e16118, 2011.

The Potential of doripenem for the treatment of infections with multidrug-resistant Pseudomonas sp..

R. Naesens, H. Jansens, E. Vlieghe, H. Goossens, M. Ieven.

International Journal of Antimicrobial Agents, 2011.

E-Bug: implementation of e-BUG in Belgium.

N. Adriaenssens, S. De Corte, S. Coenen, E. Grieten, H. Goossens.

Journal of Antimicrobial Chemotherapy  66 (Suppl. 5):v51-3, 2011.

Clinical potential of intravenous neural stem cell delivery for treatment of neuro-inflammatory disease in mice?

K. Reekmans, J. Praet, N. De Vocht, B. Tambuyzer, I. Bergwerf, J. Daans, V. Baekelandt, G Vanhoutte, H. Goossens, P. Jorens, D. Ysebaert, S. Chatterjee, P. Pauwels, E. Van Marck, Z. Berneman, A. Van der Linden, P. Ponsaert.

Cell transplantation 20: 851 – 869, 2011.

Drug utilization 75% (DU75%) in 17 European Hospitals (2000 -2005): Results from the ESAC-2 Hospital Care Sub Project.

P. Zarb, F. Ansari, A. Muller, V. Vankerckhoven, PG Davey, H. Goossens.

Curr Clin Pharmacology 6:62-70, 2011.

Antibiotic prescribing for discoloured sputum in acute cough/LRTI.

CC Butler, M. Kelly, K. Hood,T. Schaberg, H. Melby, M. Serra-Prat, F. Blasi, P. Little, T. Verheij, S. Mölstad, M. Godycki-Cwirko, P. Edwards, J. Almirall, A.Torres,U-M. Rautakorpi, J. Nuttall,  H. Goossens, S. Coenen.

Eur Resp J 38:119-25, 2011.

Antibiotic prescribing for adults with acute cough: congruence with guidelines in European primary care.

J. Wood, C.. Butler, K. Hood, . M. Kelly, T. Verheij, P. Little, A. Torres, F. Blasi, T. Schaberg, H. Goossens, J. Nuttall, S. Coenen.

Eur Resp J ;38:112-8, 2011

Towards clinical definitions of LRTI for research and primary care practice in Europe: An international consensus study.

G. Greene, K. Hood, P. Little, T. Verheij, H. Goossens, S. Coenen, CC. Butler.

Prim Care Resp J 2011; 20:299-306.

European Surveillance of Antimicrobial Consumption (ESAC): Value of a Point-Prevalence Survey of antimicrobial use across Europe.

P. Zarb, H. Goossens.Drugs, 71:745 – 755, 2011.

Society’s failure to protect a precious resource: antibiotics. 

Carlet, P. Collignon, D. Goldmann, H. Goossens, I Gyssens, S. Harbarth, V. Jarlier, S. Levy, B. N’Doye, D. Pittet,R. Richtmann, W. Seto, J. WM van der Meer, A. Voss.

Lancet, 378: 369-71, 2011.

Expert-Proposed European strategies to monitor and control infections, antibiotic use and resistance in health-care facilities.

H. Goossens.

Lancet Infectious Diseases, April 7th , 2011

Ziektespecifieke kwaliteitsindicatoren voor ambulant antibioticagebruik.

N. Adriaenssens, S.Coenen, S. Tonkin-Crine, T. Verheij, P Little, H. Goossens.

Huisarts Nu, 40(9): 390-395, 2011

Restricting Antimicrobial Use in Food Animals: Lessons from the European Union.

Banning nonessential antibiotic uses in food animals is intended to reduce pools of resistance gene

C. Cogliani, H. Goossens, and C. Greko.

Microbe, 6: 274 – 280, 2011.

Parenteral versus Oral Administration of Systemic Antimicrobials in European Nursing Homes

E.Broex, B. Catry, K. Latour, K. Mertens, V. Vankerckhoven, A. Muller, R.Stroobants, H. Goossens, B. Jans.

Drugs and aging 28: 809 – 818, 2011

The appropriateness of prescribing antibiotics in the community in Europe: study design

E. van Bijnen, C. den Heijer, J. Paget, E. Stobberingh, R. A. Verheij, C. A Bruggeman, M. Pringle, H. Goossens and F. Schellevis.BMC Infectious Diseases  11:293-297, 2011.

European Surveillance of Antimicrobial Consumption (ESAC): outpatient antibiotic use in Europe (1997-2009).

N. Adriaenssens, S. Coenen, A. Versporten, A. Muller, G. Minalu, C. Faes, V. Vankerckhoven, M. Aerts, N. Hens; G. Molenberghts and H. Goossens on behalf of the ESAC Project Group.

Journal of Antimicrobial Chemotherapy 66(suppl 6) : vi3-Vi12, 2011.

European Surveillance of Antimicrobial Consumption (ESAC): outpatient penicillin use in Europe (1997-2009).

A. Versporten, S. Coenen, N. Adriaenssens, A. Muller, G. Minalu, C. Faes, V. Vankerckhoven, M. Aerts, N. Hens, G. Molenberghs and H. Goossens on behalf of the ESAC Project Group.

Journal of Antimicrobial Chemotherapy 66(suppl 6) : vi13-Vi24, 2011.

European Surveillance of Antimicrobial Consumption (ESAC): Outpatient cephalosporin use in Europe (1997-2009).

A. Versporten, S. Coenen, N. Adriaenssens, A. Muller, G. Minalu, C. Faes, V. Vankerckhoven, M. Aerts, N. Hens, G. Molenberghs and H. Goossens on behalf of the ESAC Project Group.

Journal of Antimicrobial Chemotherapy 66(suppl 6) : vi25-Vi36, 2011.

European Surveillance of Antimicrobial Consumption (ESAC): outpatient macrolide, lincosamide and streptogramin (MLS) use in Europe (1997-2009).

N. Adriaenssens, S. Coenen, A. Versporten, A. Muller, G. Minalu, C. Faes, V. Vankerckhoven, M. Aerts, N. Hens, G. Molenberghs and H. Goossens on behalf of the ESAC Project Group.

Journal of Antimicrobial Chemotherapy 66(suppl 6) : vi37-Vi46, 2011.

European Surveillance of Antimicrobial Consumption (ESAC): Outpatient quinolone use in Europe (1997-2009).

N. Adriaenssens, S. Coenen, A. Versporten, A. Muller, G. Minalu, C. Faes, V. Vankerckhoven, M. Aerts, N. Hens, G. Molenberghs and H. Goossens on behalf of the ESAC Project Group.

Journal of Antimicrobial Chemotherapy 66(suppl 6) : vi47-Vi56, 2011.

European Surveillance of Antimicrobial Consumption (ESAC): Outpatient use of tetracyclines, sulphonamides an trimethoprim, and other antibacterials in Europe (1997-2009).

S. Coenen, N. Adriaenssens, A. Versporten, A. Muller, G. Minalu, c. Faes, V. Vankerckhoven, M. Aerts, N. Hens, G. Molenberghs and H. Goossens on behalf of the ESAC Project Group.

Journal of Antimicrobial Chemotherapy 66(suppl 6) : vi57-Vi70, 2011

European Surveillance of Antimicrobial Consumption (ESAC): Quality appraisal of antibiotic use in Europe.

N. Adriaenssens, S. Coenen, A. Versporten, A. Muller, V. Vankerckhoven and H. Goossens on behalf of the ESAC Project Group.

Journal of Antimicrobial Chemotherapy 66(suppl 6) : vi71-Vi78, 2011

Application of mixed-effects models to study the country-specific outpatient  antibiotic use in Europe: a tutorial on longitudinal data analysis.

G. Minalu, M. Aerts, S. Coenen, A. Versproten, A. Muller, N. Adriaenssens, Ph. Beutels, G. Molenberghs, H. Goossens and N. Hens.

Journal of Antimicrobial Chemotherapy 66(suppl 6) : vi79-Vi88, 2011

Analysisng the composition of outpatient antibiotic use: a tutorial on compositional data analysis.

C. Faes, G. Molenberghs, N. Hens, A. Muller, H. Goossens and S. Coenen.

Journal of Antimicrobial Chemotherapy 66(suppl 6) : vi89-Vi94, 2011

Identification for antimicrobial prescribing in European nursing homes: results from a point prevalence survey.

K. Latour, B. Catry, E. Broex, V. Vankerckhoven, A. Muller, R. Stroobants, H. Goososens, B. Jans and on behalf of the European surveillance of Antimicrobial Consumption Project Group.

Pharmacoepidiemiology and drug safety DOI:10.1002/pds.3196, 2011

European Surveillance of Antimicrobial Consumption (ESAC): Systemic antiviral use in Europe.

N.  Adriaenssens, S. Coenen, L. Kroes, A. Versporten, V. Vankerckhoven, A. Muller, H. Blix, and H. Goossens behalf of the ESAC Project Group.

Journal of Antimicrobial Chemotherapy; 66: 1897-905, 2011.

Antimicrobial Prescribing in European Nursing Homes.P. McClean, C. Hughes, M Tunney, H. Goossens, B. Jans. European Surveillance of Antimicrobial Consumption (ESAC) Nursing Home Project Group.

Journal of Antimicrobial Chemotherapy. Jul;66(7):1609-16, 2011

The body gets used to them’: patients’ interpretations of antibiotic resistance and the implications for containment strategies.L. Brookes-Howell, G. Elwyn, K. Hood, F. Wood, L. Cooper, H. Goossens, M. Ieven, C. Butler.

Journal of  General Internal Medicine. Nov 8, 2011.

Evaluation of GeneOhm VanR and Xpert vanA/vanB molecular assays for rapid detection of vancomycin-resistant enterococci.

M. Gazin, C. Lammens, H. Goossens and S. Malhotra-Kumar; on behalf of the MOSAP WP2 Study Team.

European  Journal of Clinical Microbiology Infectectious Diseases, 31(3): 273-276, 2011.

Dissemination of the NDM-2-producing Acinetobacter baumannii clone in an

Israeli Rehabilitation Center.

P. Espinal, G. Fugazza, Y. López, M. Kasma, Y. Lerman, S. Malhotra-Kumar , H.

Goossens, Y. Carmeli and J. Vila.Antimicrobial Agents Chemotherapy, 55(11): 5396-8, 2011.

Culture-based detection of methicillin-resistant Staphylococcus aureus by a network of European laboratories: An external quality assessment study.

M. Gazin, A. Lee, L. Derde, M. Kazma, C Lammens, M. Ieven, M. Bonten, T? Carmeli, s. Harbarth, C. Brun-Buisson, H. Goossens, S. Malhotra-Kumar; on behalf of the MOSAR WP2 Study Team.

Eur J clin Microbiol Infect dis, Dec 11: 2011.

A point prevalence survey of antibiotic use in four acute care teaching hospitals utilising the European Surveillance of Antimicrobial Consumption (ESAC) audit tool.

M. A. Aldeyab, M. P. Kearney, J. C. McElnay, F.A. Magee, G. Conlon, J. MacIntyre, B. Cullagh, C. Ferguson, A. Friel, C. Gormley, T. Boyce, A. McCorry, A. Muller, H. Goossens, M. G. Scott.Epidemiol Infect. Nov 24:1-7, 2011.

GPs' views in five European countries of interventions to promote prudent antibiotic use.

S. Tonkin-Crine, L. Yardley,S. Coenen, P. Fernandez-Vandellos, J. Krawczyk, P. Touboul, T. Verheij, P. Little.

Br J Gen Pract ;61:e252-e261, 2011.

Antibiotica bij acute hoest in de eerste lijn in Europa. In overeenstemming met de richtlijnen?

J. Wood, C. Butler, K. Hood, M. Kelly, T. Verheij, P. Little, A. Torres, F. Blasi, T. Schaberg, H. Goossens, J. Nuttall, S. Coenen.

Huisarts Nu ;40:384-5, 2011.

Gekleurd sputum bij acute hoest en lageluchtweginfecties. Reden om antibiotica voor te schrijven?

 C.Butler, M. Kelly, K. Hood, et al.

Huisarts Nu 40:386-7, 2011.

Interventies om doelmatig antibioticagebruik te bevorderen. Opvattingen van huisartsen in vijf Europese landen

S. Tonkin-Crine, L. Yardley, S. Coenen, P. Fernandez-Vandellos, J. Krawczyk, P. Touboul, T. Verheij, P. Little .

Huisarts Nu 40:382-3, 2011.

Diagnostics as essential tools for containing antibacterial resistance.

Okeke IN, Peeling RW, Goossens H, Auckenthaler R, Olmsted SS, de Lavison JF, Zimmer BL, Perkins MD, Nordqvist K.

Drug Resist Updat. 2011;14(2):95-106. Epub 2011 Mar 12.

Antibiotic management of febrile neutropenia: Current developments and future directions.

J. Mebis, H. Goossens, Z. Berneman.

Journal of Chemotherapy; 22: 5-12, 2010.

Characteristics and outcomes of public health campaigns with the aim to improve outpatient antibiotic use in high income countries.

B. Huttner, H. Goossens, T. Verheij and S. Harbarth.

Lancet Infectious Disases 10:17-31, 2010.

Antimicrobial-resistant pathogens in animals and man: prescribing practices and policies.

PA Hunter, S.Dawson, GL French, H. Goossens, PM. Hawkey, Ed J. Kuijper, D. Nathwani, DJ Taylor, CJ Teale, RE Warren, MH Wilcox, N. Woodford, MW Wulf and L.JV Piddock.

Journal of Antimicrobial Chemotherapy 65, suppl 1: 3-17, 2010.

Long-term epidemiology of bacterial susceptibility profiles in adults suffering from frebile neutropenia with hematologic malignancy after antibiotic change.

J. Mebis, H. Jansens, G. Minalu, G. Molenberghs, WA Schroyens, A.. Gadisseur, A. van de Velde, I. Vrelust, H. Goossens, and Z.N. Berneman.

Infection and Drug resistance 3: 53-61, 2010.

Cefepime and mortality: a real issue?

J. Mebis, H. Goossens, Z.N. Berneman.

Scandinavian Journal of Infectious Diseases, 42, 6-7: 545-548, 2010.

Are smokers with cough in primary care prescribed antibiotics more often, and to what benefit? An observational study in 13 European countries.

N. Stanton, K. Hood, M.J. Kelly, J. Nuttall, D. Gillespie, T. Verheij, P. Little, M; godycki-Cwirko, H. Goossens, CC Butler.

European Respiratory Journal, 35: 761-767, 2010.

Induction of complete and molecular remissions in acute myeloid leukemia by Wilms’ tumor 1 antigen-targeted dendritic cell vaccination.

V.F. Van Tendeloo, A. Van de Velde, A. Van Driessche, N. Cools, S. Anguille, K. Ladell, E. Gostick, K. Vermeulen, K. Pieters, G. Nijs, B. Stein, E. Smits, W. Schroyens, A. Gadisseur, I. Vrelust, P. Jorens, H. Goossens, J. de Vries, D. Price, Y. Oji, Y. Oka, H. Sugiyama, and Z. Bernemanl.

PNAS Early Edition 1-6,  2010.

Evaluation of molecular assays for rapid detection of methicillin-resistant Staphylococcus aureus.

S. Malhotra-Kumar, H.L. Van, A. Lee, J.C. Abrahantes, C. Llammens, E. Vanhommerig, G. Molenberghs, M. Aerts, S. Harbarth and H. Goossens.

J. Clin. Microbiol. 48:4598-4601, 2010.

Identification of targets for quality improvement in antimicrobial prescribing: the web-based ESAC Point Prevalence Survey 2009.

P. Zarb, B. Amadeo, A. Muller, N. Drapier, V. Van Kerckhoven, P. Davey and H. Goossens on behalf of the ESAC-3 hospital care subproject Group.

Journal of Antimicrobial Chemotherapy 65: 443-449, 2010.

European surveillance of antibiotic consumption (ESAC) point prevalence survey 2008: paediatric antimicrobial prescribing in 32 hospitals of 21 European countries.

B. Amadeo, P. Zarb, A. Muller, N. Drapier, V. Vankerckhoven, A-M Rogues, P. Davey and H. Goossens on behalf of the ESAC III Hospital Care Subproject Group.

Journal Antimicrob Chemoter 65: 2247-2252, 2010.

Treatment of acute cough/LRTI by antibiotic class and associated outcomes: A 13 European country observational study in primary care.

C. Butler, K. Hood, H. Goossens, M. Kelly, T. Verheij.

Journal of Antimicrobial Chemotherapy 65(11): 2472-2478, 2010.

Development of standardised methods for analysis of changes in antibacterial use in hospitals from 18 European countries: the European  Surveillance of Antimicrobial Consumption (ESAC) longitudinal survey 2000 to 2006.F. Ansari, H. Molana, H. Goossens, P. Davey.

Journal of Antimicrobial Chemotherapy 65: 2685-2691, 2010.

Characteristics and outcomes of public health campaigns with the aim to improve outpatient antibiotic use in high income countries.

B. Huttner, H. Goossens, T. Verheij and S. Harbarth.

Problemy Medycyny Rodzinne J, 12(4) 35-53,  2010.

Acute respiratory infection due to Mycoplasma pneumonia: current status of diagnostic methods.

K. Loens, H. Goossens, M. Ieven.

Eur J Clin Microbiol Infect Dis.;29(9):1055-69, 2010.

A  multicenter pilot external quality assessment programme to assess the quality of molecular detection of Chlamydophila pneumonia and Mycoplasma pneumonia.

K. Loens, G. Ieven, H. Goossens, C. Scott, W. Mackay.

J Microbiol Methods.;82(2):131-5., 2010

Socioeconomic determinants of outpatient antibiotic use in Europe.

G. Masiero, M. Filippini, M. Ferech, H. Goossens.

Int J Public Health. Oct;55(5):469-78, 2010.

Kort Nieuws: Doen andere of geen antibiotica het beter dan amoxicilline bij acute hoest?

 S. Coenen.

Huisarts Nu 39:333, 2010.