Laboratory of Experimental Medicine and Pediatrics

The Laboratory of Experimental Medicine and Pediatrics (LEMP) incorporates 7 clinical divisions united around the topic of inflammation and has a strong track record in a broad range of diseases affecting several organs including the lungs, gastrointestinal tract, liver, pancreas, kidneys, endocrine glands, and fat tissue, both in adults and children. Furthermore, as inflammation is one of the hallmarks of cancer, special attention is also given to cancer research.

Head of LEMP is prof dr Benedicte De Winter

LEMP Clinical Divisions:

Overlapping cortical malformations in patients with pathogenic variants in GRIN1 and GRIN2B

Source
Journal of medical genetics - ISSN 0022-2593-60 (2023) p. 183-192
Author(s)
    Stefanie Brock, Annie Laquerriere, Florent Marguet, Scott J. Myers, Yuan Hongjie, Diana Baralle, Tim Vanderhasselt, Katrien Stouffs, Kathelijn Keymolen, Sukhan Kim, James Allen, Gil Shaulsky, Jamel Chelly, Pascale Marcorelle, Jacqueline Aziza, Laurent Villard, Elise Sacaze, Marie C.Y. de Wit, Martina Wilke, Grazia Maria Simonetta Mancini, Ute Hehr, Derek Lim, Sahar Mansour, Stephen F. Traynelis, Claire Beneteau, Marie Denis-Musquer, Anna Jansen, Andrew E. Fry, Nadia Bahi-Buisson

Health-related quality of life of children born very preterm : a multinational European cohort study

Source
Quality of life research - ISSN 0962-9343-23:1 (2023) p. 47-58
Author(s)
    Sung Wook Kim, Lazaros Andronis, Anna-Veera Seppänen, Adrien M. Aubert, Henrique Barros, Elizabeth S. Draper, Mariane Sentenac, Jennifer Zeitlin, Stavros Petrou, Jo Lebeer, Patrick Van Reempts, E. Bruneel, E. Cloet, A. Oostra, E. Ortibus, Iemke Sarrechia, K. Boerch, P. Pedersen, L. Toome, H. Varendi, M. Männamaa, P.Y. Ancel, A. Burguet, P.H. Jarreau, V. Pierrat, P. Truffert, R.F. Maier, M. Zemlin, B. Misselwitz, L. Wohlers, M. Cuttini, I. Croci, V. Carnielli, G. Ancora, G. Faldella, F. Ferrari, A. van Heijst, C. Koopman-Esseboom, J. Gadzinowski, J. Mazela, A. Montgomery, T. Pikuła, H. Barros, R. Costa, C. Rodrigues, U. Aden, E.S. Draper, A. Fenton, S.J. Johnson, A.V. Seppänen

Technical standards for using type III devices (limited channel studies) in the diagnosis of sleep disordered breathing in adults and children

Source
The European respiratory journal - ISSN 0903-1936-61:1 (2023) p. 1-20
Author(s)
    Renata L. Riha, Marta Celmina, Brendan Cooper, Refika Hamutcu-Ersu, Athanasios Kaditis, Andrew Morley, Athanasia Pataka, Thomas Penzel, Luca Roberti, Warren Ruehland, Dries Testelmans, Annelies van Eyck, Gert Grundström, Johan Verbraecken, Winfried Randerath

Viral clade is associated with severity of symptomatic genotype 3 Hepatitis E virus infections in Belgium, 2010-2018

Source
Journal of hepatology - ISSN 0168-8278-78:1 (2023) p. 67-77
Author(s)
    Michael Peeters, Julie Schenk, Thomas De Somer, Tania Roskams, Tatjana Locus, Sofieke Klamer, Lorenzo Subissi, Vanessa Suin, Jean Delwaide, Peter Stärkel, Stéphane De Maeght, Philippe Willems, Isabelle Colle, Marc Van Hoof, Jos Van Acker, Christophe Van Steenkiste, Christophe Moreno, Filip Janssens, Marijke Reynders, Matthias Steverlynck, Wim Verlinden, Luc Lasser, Chantal de Galocsy, Anja Geerts, Jeroen Maus, Marie Gallant, Steven Van Outryve, Astrid Marot, Hendrik Reynaert, Jochen Decaestecker, Emmanuel Bottieau, Jonas Schreiber, Jean-Pierre Mulkay, Sébastien de Goeij, Mikhaël Salame, Diederik Dooremont, Sergio Negrín Dastis, Juul Boes, Jochen Nijs, Jan Beyls, Niel Hens, Frederik Nevens, Steven Van Gucht, Thomas Vanwolleghem

Kidney transplantation during mass disasters-from COVID-19 to other catastrophes : a Consensus Statement by the DESCARTES Working Group and Ethics Committee of the ERA

Source
Nephrology, dialysis, transplantation - ISSN 0931-0509-38:2 (2023) p. 300-308
Author(s)
    Mehmet Sukru Sever, Raymond Vanholder, Gabriel Oniscu, Daniel Abramowicz, Wim Van Biesen, Umberto Maggiore, Bruno Watschinger, Christophe Mariat, Jadranka Buturovic-Ponikvar, Marta Crespo, Geir Mjoen, Peter Heering, Licia Peruzzi, Ilaria Gandolfini, Rachel Hellemans, Luuk Hilbrands

Tirzepatide for the treatment of adults with type 2 diabetes : an endocrine perspective

Source
Diabetes, obesity & metabolism - ISSN 1462-8902-25:1 (2023) p. 3-17
Author(s)
    Christophe de Block, Clifford Bailey, Carol Wysham, Andrea Hemmingway, Sheryl Elaine Allen, Jennifer Peleshok

Portal hypertension is a key determinant of the risk for liver-related events in non-alcoholic fatty liver disease

Source
Journal of hepatology - ISSN 0168-8278-73:3 (2023) p. e102-e104
Author(s)

Assessment of portal hypertension severity using machine learning models in patients with compensated cirrhosis

Source
Journal of hepatology - ISSN 0168-8278-78:2 (2023) p. 390-400
Author(s)
    Jiří Reiniš, Oleksandr Petrenko, Benedikt Simbrunner, Benedikt S. Hofer, Filippo Schepis, Marco Scoppettuolo, Dario Saltini, Federica Indulti, Tomas Guasconi, Agustin Albillos, Luis Téllez, Càndid Villanueva, Anna Brujats, Juan Carlos Garcia-Pagan, Valeria Perez-Campuzano, Virginia Hernández-Gea, Pierre-Emmanuel Rautou, Lucile Moga, Thomas Vanwolleghem, Wilhelmus Kwanten, Sven Francque, Jonel Trebicka, Wenyi Gu, Philip G. Ferstl, Lise Lotte Gluud, Flemming Bendtsen, Søren Møller, Stefan Kubicek, Mattias Mandorfer, Thomas Reiberger

Efficacy and safety in patients with haemophilia A switching to octocog alfa (BAY 81-8973) : final results of the global real-world study, TAURUS

Source
European journal of haematology - ISSN 0902-4441-110:1 (2023) p. 77-87
Author(s)
    Cristina Santoro, Beng Fuh, Phu Quoc Le, Philip Maes, Ruben Berrueco, Eva Maria Mingot-Castellano, Sylvia von Mackensen, Claudia Tueckmantel, Jose Francisco Cabre-Marquez, Michael Wang

Clinicopathological characteristics and disease chronicity in native kidney biopsies in Flanders

Source
Clinical Kidney Journal - ISSN 2048-8505-16:1 (2023) p. 125-137
Author(s)
    Dries Deleersnijder, Wim Laurens, Johan De Meester, Evert Cleenders, Amélie Dendooven, Evelyne Lerut, An S. De Vriese, Tom Dejagere, Mark Helbert, Rachel Hellemans, Priyanka Koshy, Bart Maes, Lissa Pipeleers, Amaryllis Van Craenenbroeck, Steven Van Laecke, Johan Vande Walle, Marie Madeleine Couttenye, Gert Meeus, Ben Sprangers

Effects of treatment for diabetes mellitus on testosterone concentrations : a systematic review

Source
Andrology - ISSN 2047-2919-11:2 (2023) p. 225-233
Author(s)