Laboratory of Experimental Medicine and Pediatrics

The Laboratory of Experimental Medicine and Pediatrics (LEMP) incorporates 7 clinical divisions united around the topic of inflammation and has a strong track record in a broad range of diseases affecting several organs including the lungs, gastrointestinal tract, liver, pancreas, kidneys, endocrine glands, and fat tissue, both in adults and children. Furthermore, as inflammation is one of the hallmarks of cancer, special attention is also given to cancer research.

Head of LEMP is prof dr Benedicte De Winter

LEMP Clinical Divisions:

JNJ-73763989 and bersacapavir treatment in nucleos(t)ide analog suppressed patients with chronic hepatitis B : REEF-2

Source
Journal of hepatology - ISSN 0168-8278- (2024) p.
Author(s)
    Kosh Agarwal, Maria Buti, Florian van Bömmel, Pietro Lampertico, Ewa Janczewska, Marc Bourliere, Thomas Vanwolleghem, Oliver Lenz, Thierry Verbinnen, Thomas N. Kakuda, Cristiana Mayer, John Jezorwski, Daniel Muenz, Maria Beumont, Ronald Kalmeijer, Michael Biermer, Isabelle Lonjon-Domanec

Brain function in classic galactosemia, a galactosemia network (GalNet) members review

Source
Frontiers in genetics - ISSN 1664-8021-15 (2024) p. 1-11
Author(s)
    Bianca Panis, E. Naomi Vos, Ivo Baric, Annet M. Bosch, Martijn C.G.J. Brouwers, Alberto Burlina, David Cassiman, David J. Coman, Maria L. Couce, Anibh M. Das, Didem Demirbas, Aurelie Empain, Matthias Gautschi, Olga Grafakou, Stephanie Grunewald, Sandra Kingma, Ina Knerr, Elisa Leao-Teles, Dorothea Moeslinger, Elaine Murphy, Katrin Ounap, Adriana Pane, Sabrina Paci, Rossella Parini, Isabel A. Rivera, Sabine Scholl-Buergi, Ida V. D. Schwartz, Triantafyllia Sdogou, Loai A. Shakerdi, Anastasia Skouma, Karolina M. Stepien, Eileen P. Treacy, Susan Waisbren, Gerard T. Berry, M. Estela Rubio-Gozalbo

Implementation of a liver health check in people with type 2 diabetes

Source
Lancet gastroenterology & hepatology - ISSN 2468-1253-9:1 (2024) p. 83-91
Author(s)
    Kushala W.M. Abeysekera, Luca Valenti, Zobair Younossi, John F. Dillon, Alina M. Allen, Mazen Noureddin, Mary E. Rinella, Frank Tacke, Sven Francque, Pere Gines, Maja Thiele, Philip N. Newsome, Indra Neil Guha, Mohammed Eslam, Joern M. Schattenberg, Saleh A. Alqahtani, Marco Arrese, Annalisa Berzigotti, Adriaan G. Holleboom, Cyrielle Caussy, Kenneth Cusi, Michael Roden, Hannes Hagstroem, Vincent Wai-Sun Wong, Vincent Mallet, Laurent Castera, Jeffrey V. Lazarus, Emmanuel A. Tsochatzis

Natural history of three late-diagnosed classic Galactosemia patients

Source
Molecular Genetics and Metabolism Reports - ISSN 2214-4269-38 (2024) p. 1-5
Author(s)
    Dulce Quelhas, Sandra Kingma, An Jonckheere, Claudia S. Smeets-Peels, Daniel Costa Gomes, Jose Duro, Anabela Oliveira, Gert Matthijs, Laura K.M. Steinbusch, Jaak Jaeken, Isabel Rivera, Estela Rubio-Gozalbo

Evaluation of glucose metrics in adults with type 1 diabetes switching to insulin glargine 300 U/mL : a retrospective, propensity-score matched study

Source
Diabetes technology and therapeutics - ISSN 1520-9156- (2024) p.
Author(s)
    Sara Charleer, Steffen Fieuws, Christophe de Block, Nancy Bolsens, Frank Nobels, Kristian Mikkelsen, Chantal Mathieu, Pieter Gillard

Role of upper airway evaluation in the multidisciplinary management of obstructive sleep apnea in children below two years of age

Source
Pediatric pulmonology - ISSN 8755-6863- (2024) p.
Author(s)

Long-term efficacy and safety of pitolisant for residual sleepiness due to OSA

Source
Chest - ISSN 0012-3692-165:3 (2024) p. 692-703
Author(s)
    Jean-Louis Pépin, Valérie Attali, Christian Caussé, Johan Verbraecken, Jan Hedner, Isabelle Lecomte, Renaud Tamisier, Patrick Lévy, Philippe Lehert, Yves Dauvilliers

Efficacy and safety of elafibranor in primary biliary cholangitis

Source
The New England journal of medicine - ISSN 0028-4793-390 (2024) p. 795-805
Author(s)
    Kris V. Kowdley, Christopher L. Bowlus, Cynthia Levy, Ulus S. Akarca, Mario Reis Alvares-da-Silva, Pietro Andreone, Marco Arrese, Christophe Corpechot, Sven Francque, Michael A. Heneghan, Pietro Invernizzi, David Jones, Frederik C. Kruger, Eric Lawitz, Marlyn J. Mayo, Mitchell L. Shiffman, Mark G. Swain, Jose Miguel Valera, Victor Vargas, John M. Vierling, Alejandra Villamil, Carol Addy, Julie Dietrich, Jean-Michel Germain, Sarah Mazain, Dragutin Rafailovic, Bachirou Tadde, Benjamin Miller, Jianfen Shu, Claudia O. Zein, Jorn M. Schattenberg

Learnings from the graveyard of phase 2 and 3 nonalcoholic steatohepatitis trials

Source
Clinical gastroenterology and hepatology - ISSN 1542-3565-22:1 (2024) p. 16-19