LEMP

The Laboratory of Experimental Medicine and Pediatrics (LEMP) is a multidisciplinary research team that incorporates the fundamental, clinical and translational research activities of 7 research laboratories of the Faculty of Medicine and Health Sciences at the University of Antwerp.

Head of LEMP is prof dr Benedicte De Winter

LEMP includes the research laboratories of:

  • Endocrinology, Diabetology and Metabolic diseases (Head: prof dr Christophe De Block)
  • Gastroenterology & Hepatology (Head: prof dr Sven Francque)
  • Intensive care (Head: prof dr Philippe Jorens)
  • Neonatology (Head: prof dr Antonius Mulder)
  • Nephrology (Head: prof dr Daniel Abramowicz)
  • Pediatrics (Head: prof dr Stijn Verhulst)
  • Pneumology (Head: prof dr Jan van Meerbeeck)

 

Recent publications

  • Autophagy determines efficiency of liver-directed gene therapy with adeno-associated viral vectors.

    Hepatology. 2017 Jul;66(1):252-265. doi: 10.1002/hep.29176. Epub 2017 May 29.

    Hösel M1,2, Huber A1,2, Bohlen S3, Lucifora J4, Ronzitti G5, 

    Puzzo F5, Boisgerault F5, Hacker UT6, Kwanten WJ7, Klöting N8, Blüher M9, 

    Gluschko A1,3, Schramm M1,3, Utermöhlen O1,3, Bloch W10,F5,11, 

  • Immediate moxiflixin hypersensitivity: Is there more than currently meets the eye

    https: //doi.org/10.1111/all.13236

    Van Gasse AL, Sabato V, Uyttebroek AL, et al

  • Interferon-alpha treatment rapidly clears Hepatitis E virus infection in humanized mice

     https://www.nature.com/articles/s41598-017-07434-y.

     Martijn D.B. van de Garde, Suzan D. Pas, Gertine W. van Oord, Lucio Gama,

     Youkyung Choi, Robert A. de Man, Andre Boonstra , Thomas Vanwolleghem  

  • Circulating predictive and diagnostic biomarkers for hepatitis B virus-associated hepatocellular carcinoma.

     World J Gastroenterol 2016; 22(37): 8271-8282

    Van Hees S, Michielsen P, Vanwolleghem T

  • Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice.

     http://www.ncbi.nlm.nih.gov/pubmed/27514483

     Kwanten WJ, Vandewynckel YP, Martinet W, De Winter BY, Michielsen PP,

     Van Hoof VO, Driessen A, Timmermans JP, Bedossa P, Van Vlierberghe H,Francque SM

  • Non-Alcoholic Fatty Liver Disease and Cardiovascular Risk: Pathophysiological Mechanisms and Implications

    http://www.journal-of-hepatology.eu/article/S0168-8278(16)30107-6/

     Sven M. Francque,Denise van der Graaff, Wilhelmus J. Kwanten

                                                                                                                                                                                                                   


     

Key publications

Phenotypic and functional characterization of in vitro cultured human mast cells
Cop Nathalie   Decuyper Ine   Faber Margaretha   Sabato Vito   Bridts Christiaan   Hagendorens Margo   De Winter Benedicte   De Clerck Luc S.   Ebo Didier  
Cytometry: part B: clinical cytometry - ISSN 1552-4949-92:5 (2017) p. 348-354
Citatielink
IgE-reactivity profiles to nonspecific lipid transfer proteins in a northwestern European country
Faber Margaretha   Van Gasse Athina L.   Decuyper Ine   Uyttebroek Astrid   Sabato Vito   Hagendorens Margo   Bridts Christiaan   De Clerck Luc S.   Fernandez-Rivas Montserrat   Pascal Mariona   Diaz-Perales Araceli   Ebo Didier  
The journal of allergy and clinical immunology - ISSN 0091-6749-139:2 (2017) p. 679-682
Citatielink
Genome-wide association study of acute renal graft rejection
Ghisdal L.   Baron C.   Lebranchu Y.   Viklicky O.   Konarikova A.   Naesens M.   Kuypers D.   Dinic M.   Alamartine E.   Touchard G.   Antoine T.   Essig M.   Rerolle J. P.   Merville P.   Taupin J. L.   Le Meur Y.   Grall-Jezequel A.   Glowacki F.   Noel C.   Legendre C.   Anglicheau D.   Broeders N.   Coppieters W.   Docampo E.   Georges M.   Ajarchouh Z.   Massart A.   Racape J.   Abramowicz Daniel   Abramowicz M.  
American journal of transplantation - ISSN 1600-6135-17:1 (2017) p. 201-209
Citatielink
Induction therapy for kidney transplant recipients : do we still need anti-IL2 receptor monoclonal antibodies?
Hellemans Rachel   Bosmans Jean-Louis   Abramowicz Daniel  
American journal of transplantation - ISSN 1600-6135-17:1 (2017) p. 22-27
Citatielink
Bone histomorphometry in de novo renal transplant recipients indicates a further decline in bone resorption 1 year posttransplantation
Evenepoel Pieter   Behets Geert   Viaene Liesbeth   d' Haese Patrick C.  
Kidney international - ISSN 0085-2538-91:2 (2017) p. 469-476
Citatielink

Full bibliography of this research group

Contact

LEMP Director:
Benedicte De Winter
University of Antwerp
Fac. Medicine & Health Sciences
Universiteitsplein 1
B-2610 Antwerp,
Belgium
benedicte.dewinter@uantwerpen.be

Contact

Secretary:
Jessy Michiels
Campus Drie Eiken
Gebouw T 3.30
Universiteitsplein 1
B-2610 Antwerp
Belgium
Tel. +32 3 265 26 32
Jessy.michiels@uantwerpen.be