Research team

Expertise

Expertise in the domains of digital image processing and analysis, statistical pattern recognition, processing of MRI images (fMRI, DTMRI), processing of remote sensing data.

3D picometrology : new routes to explore the atomic arrangement using state-of-the-art electron microscopy 01/01/2013 - 31/12/2016

Abstract

The goal of this project is therefore to develop and apply quantitative methods in order to visualize and identify atoms and next to precisely measure their positions in three dimensions. This will open up a whole new range of possibilities to understand and characterize nanocrystals at the atomic level and to help developing innovative materials with revolutionary interesting properties.

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  • Research Project

Better homecare with "eZorg Interactive Communication Platform". 01/07/2012 - 31/03/2014

Abstract

This project represents a formal research agreement between UA and on the other Landelijke Thuiszorg vzw. UA provides Landelijke Thuiszorg vzw research results mentioned in the title of the project under the conditions as stipulated in this contract.

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  • Research Project

Establishment of the Interfaculty Centre for Health Technology. 10/01/2012 - 31/12/2012

Abstract

This project represents a formal research agreement between UA and on the other hand KdG. UA provides KdG research results mentioned in the title of the project under the conditions as stipulated in this contract.

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  • Research Project

Study of innovative technologies for increasing the comfort, reliability and standardization of the Handi-Move interface. 01/09/2010 - 30/09/2011

Abstract

This project represents a formal research agreement between UA and on the other hand Handi-Move. UA provides Handi-Move research results mentioned in the title of the project under the conditions as stipulated in this contract.

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  • Research Project

Counting atoms. 01/01/2010 - 31/12/2013

Abstract

This is a fundamental research project financed by the Research Foundation - Flanders (FWO). The project was subsidized after selection by the FWO-expert panel.

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  • Research Project

Nanosciences Live in Science Centres and Museums (NANO TO TOUCH). 01/03/2009 - 31/08/2011

Abstract

This project represents a formal research agreement between UA and on the other hand EU. UA provides EU research results mentioned in the title of the project under the conditions as stipulated in this contract.

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  • Research Project

Electron microscopy for materials research (NANOcenter). 01/01/2009 - 31/12/2014

Abstract

This project represents a research contract awarded by the University of Antwerp. The supervisor provides the Antwerp University research mentioned in the title of the project under the conditions stipulated by the university.

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  • Research Project

Quantitative analysis of in vivo multimodal and multitemporal images: from animal models to novel medical applications (QUANTIVIAM). 01/01/2008 - 31/12/2011

Abstract

This project represents a research agreement between the UA and on the onther hand IWT. UA provides IWT research results mentioned in the title of the project under the conditions as stipulated in this contract.

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  • Research Project

Optimal experimental design for quantitative electron microscopy. 01/01/2008 - 31/12/2011

Abstract

The aim of this research project is to apply state-of-the-art methods from the oprimal design of experiments in the field of elektron microscopy. These methods will allow electron microscopists to evaluate, to compare, and to optimize experiments in terms of the attainable precision with which structure parameters, the atom positions in particular, can be measured. Moreover, statistical experimental design provides the possibility to decide if new instrumental developments result in significantly higher attainable precisions. The highest attainable precision determines the theoretical limit to quantitative electron microscopy.

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  • Research Project

Model-based electron microscopy: From visual interpretation of the observations toward precise measurements of physical structure parameters. 01/10/2007 - 30/09/2009

Abstract

The aim of this project is to realize a breakthrough toward quantitative, model-based electron microscopy so as to obtain precise measurements of physical structure parameters from the observations. From theoretical as well as from experimental point of view, this is the project's goal. On the one hand, this means that the methodology will be further improved and optimized and on the other hand, it will be shown that precise measurements are attainable in practice by applying the methodology to experimental observations.

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  • Research Project

Condor. 01/02/2007 - 31/12/2010

Abstract

The Condor project will take up research on the model driven development of systems that are governed by complex physics and have to comply with severe performance requirements. it will concentrate on systems that - incorporate intricate and delicately interrelated physics; - are very sensitive to implementation details and imperfections and to external disturbances.

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  • Research Project

Centre of Expertise R&D indicators (2007-2011). 01/01/2007 - 31/12/2008

Abstract

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    • Research Project

    FWO Visiting Postdoctoral Fellowship. (Kees BATENBURG, Netherlands) 01/10/2006 - 30/09/2007

    Abstract

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    • Research Project

    Electron microscopy for the improvement of the academic competitiveness in Peru. 01/07/2006 - 30/06/2011

    Abstract

    The low competitiveness of Peru is one of the major development problems of the County. One of the important causes of the low competitiveness is the lack of a solid scientific and technical capacity in the county that can allow the creation of the research - development - innovation chain. Mining & metallurgy is the main activity of the country, it provides the 50% of the county revenues; however no research activity is developed in this sector relthed to materials characterization and products are basically exported as raw material without added value. The current project aims to contribute in the establishment of a research group with an intemàtional level in electron microscopy for materials research with emphasis in nanoscience. The Group will operate at PC-TIM and ]PEN improving the Peruvian scientific production through the publication of scientific & technical papers and training students and professionals in research activities at international standard levels. At the end of the project we expect to have a critical number of researchers in order to make sustainable the research activities in the field, As collateral mid term result, it is expected that the research team will gain prestige and credibility in order to pay attention from the national industry, deserving financial support for research and educational activities.

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    • Research Project

    Electron microscopy for materials research (NANOcenter). 01/05/2006 - 31/12/2008

    Abstract

    This project represents a research contract awarded by the University of Antwerp. The supervisor provides the Antwerp University research mentioned in the title of the project under the conditions stipulated by the university.

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    • Research Project

    Audiovisual systems. 01/01/2006 - 31/12/2010

    Abstract

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    • Research Project

    Development of improved techniques for the analysis of functional magnetic resonance data. 01/10/2005 - 30/09/2008

    Abstract

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    • Research Project

    Quantitative analysis of electron energy loss spectroscopy of nanostructures. 01/10/2005 - 30/09/2007

    Abstract

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    • Research Project

    ICA4DT- Image based Computer Assistance for Diagnosis and Therapy. 01/09/2005 - 31/12/2007

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    • Research Project

    Efficient non-linear smallest quadrates methods for sinusoidal modeling of audio and speech (type 1). 01/02/2005 - 31/01/2008

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    • Research Project

    Quantitative atomic resolution electron tomography : a challenge for precise, three-dimensional, atomic structure determination of aperiodic structures. 01/01/2005 - 31/12/2008

    Abstract

    The aim of the project is to realize a breakthrough toward quantitative atomic resolution electron tomography in order to measure the local, three-dimensional structure of aperiodic materials as precisely as possible. For the validation of theoretical models, a precision of the atom positions of the order of 0.01 to 0.001 nm is required.

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    • Research Project

    Weathering of blue and purple enamels: an old problem studied with the newest techniques. 01/02/2004 - 31/12/2005

    Abstract

    The project aims to study the relation between the chemical composition of blue and purple enamels, of the substrate glass they are applied upon and the wheathering processes these materials are subject to, that are part of historical stained glass windows.

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    • Research Project

    Geometrical aspects in industrial vision applications. 01/02/2004 - 31/12/2005

    Abstract

    In many industrial vision settings one makes use of an image sequence. These multiple view systems give rise to specific questions on: -the required geometric calibration in order to perform measurements . -corresponding points/line segments/regions , -the relative camera motion between successive views , -the 3D-reconstruction of objects , The literature on computer vision offers an extensive treatment of these topics, however often formulated in advanced algebraic and geometric terms. It is our goal to translate the theory into ad hoc algorithms, directly applicable to a given industrial environment.

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    • Research Project

    Study of a spectroscopic electrical impedance tomography technique for diagnosis of dental caries. 01/01/2004 - 31/12/2007

    Abstract

    The significant decline in the incidence of dental caries that is observed in the last two decades [Sawle et al., 1988] [Kalsbeek et al., 1998], also seems to be accompanied by a distinctive change in lesion morphology. In particular, the phenomenon of slowly progressing dentinal lesions, obscured by apparently intact enamel [Kidd et al., 1992] [Poorterman et al.,1999], renders the established diagnostic procedures of visual examination and intra-oral radiography, ineffective [Poorterman et al.,2000]. However, reliable detection at an early stage of the carious progression remains crucial to allow for an appropriate preventive or minimal invasive treatment. Extraordinary sensitivity scores, however, have been achieved with diagnostic methods based on the premise that demineralized lesions show a significant higher electrical conductivity than healthy tissue, due to the phenomenon of increased pore volume. Even more impressive results were attaind by means of spectroscopic conductance measurements. Clinical application of these electrical conductivity methods, unfortunately seems to be hampered by a lack of reproducibility. Variations in conductivity readings makes it very difficult, if not impossible, to define generally applicable diagnostic thresholds for discriminating among carious involvement. It may be hypothesized, that this problem is related to the very nature of the 2-point measurement configuration underlying all of the experimental methods, described in the literature as today. This study instead, aims to develop and evaluate a new method of spectroscopic Electrical Impedance Tomography (EIT), capable of reconstructing cross-sectional maps of the coronal tooth structure, depicting site-specific electrical impedance spectra. The resulting method promises to improve upon existing electrical caries detection methods, both in terms of its improved cross-sectional sampling strategy, dispensing with the need to rely on visual surface indications to determine appropriate measurement sites, and its immunity with regard to the natural variability in electrical conductance between individual teeth. Tomographic representation of the measurement results will allow the diagnostic interpretation to proceed on the basis of relative changes in tissue impedance among different spatial locations, instead of being dependent on a single quantitative interpretation. The suggested spectroscopic extension of the established method of EIT , together with the particularly difficult measurement conditions created by the insulating properties of the outer enamel layer, will pose some very specific problems as to the mathematical demands on the reconstruction algorithms. Therefore, the study and evaluation of non-linear reconstruction algorithms for the inverse conductivity problem of EIT, based on concepts drawn from numerical algebra, will constitute the major contribution in this research proposal. Despite the fact that evaluation of the algorithmic developments will be limited to numerical simulation and in vitro experiments, design of the newly developed method will be such, that its essential properties can be expected to transfer straightforwardly to the clinical setting. To gain a more fundamental understanding of the electrical conduction phenomena taking place in dental structures, a first, morphological accurate, numerical simulation model of a whole tooth will be built. The detailed morphological input data for this model will be derived from micro-Computed Tomography (micro-CT) scans, acquired with a microfocal desktop-sized measurement system. Cross-sectional images acquired in this way, will be processed by an automatic segmentation procedure, before being converted into a 3D Finite Element (FE) mesh. Such a mesh description allows to build up the actual volumetric simulation model.

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    • Research Project

    Shape reconstruction and characterization. 01/01/2004 - 31/12/2007

    Abstract

    The problems of reconstruction and characterization of the shape of an object or region are ubiquitous in computational science, engineering and computer vision. Important tools in solving these problems are moments and Fourier descriptors. Both have proved to be very useful in respectively shape reconstruction and characterization. From the literature on the shape-from-moments reconstruction problem, one can see that until recently the shape inverting problem was tackled using univariate techniques in one complex variable. This approach imposes restrictions on the shape of the object under reconstruction as well as on the dimensionality of the problem. Our aim is on one hand to further explore the three-dimensional problem, using true multidimensional techniques instead of reducing the problem to one-dimensional subproblems, and on the other hand to eliminate the current restrictions on the shape of the object under study. With respect to Fourier descriptors (FDs) used for shape characterization, interesting problems remain to be solved as well. Two-dimensional (2D) FDs have been exploited from the early 70's for the characterization of the contours of 2D objects. From the 90's on, methods for the computation of 3D Fourier descriptors were developed for the characterization of the surface of binary objects. Existing methods, however, still suffer from complexity problems, especially when the number of vertices is large (>5000). In general, 3D FDs are computed by mapping the object's polyhedron onto the surface of a unit sphere, after which it is expanded in spherical harmonics. This mapping from the object space (surface) to the parameter space (sphere) is non-trivial and current techniques suffer from computational problems. Our goal is to develop a robust method which implements this mapping in an efficient way, in other words, such that the computational time grows linearly with the number of vertices.

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      • Research Project

      ATOM : Advanced Tomography. 01/01/2004 - 31/12/2007

      Abstract

      The main goal of the project is the development/improvement of advanced forms of tomography and its application in practice. On the one hand attention will be paid to the development of tomography at the nanoscopic level by means of EFTEM while on the other hand element-specific X-ray fluorescence tomography with micrometer resolution will be optimised and quantitatively calibrated. An important area of application is the quantitative three-dimensional measurement of various phases in (human and animal) bone.

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      • Research Project

      Matching fund FWO-research project: 'Study of a spectroscopic electrical impedance tomography technique for diagnosis of dental caries.' 01/10/2003 - 31/12/2007

      Abstract

      The significant decline in the incidence of dental caries that is observed in the last two decades [Sawle et al., 1988] [Kalsbeek et al., 1998], also seems to be accompanied by a distinctive change in lesion morphology. In particular, the phenomenon of slowly progressing dentinal lesions, obscured by apparently intact enamel [Kidd et al., 1992] [Poorterman et al.,1999], renders the established diagnostic procedures of visual examination and intra-oral radiography, ineffective [Poorterman et al.,2000]. However, reliable detection at an early stage of the carious progression remains crucial to allow for an appropriate preventive or minimal invasive treatment. Extraordinary sensitivity scores, however, have been achieved with diagnostic methods based on the premise that demineralized lesions show a significant higher electrical conductivity than healthy tissue, due to the phenomenon of increased pore volume. Even more impressive results were attaind by means of spectroscopic conductance measurements. Clinical application of these electrical conductivity methods, unfortunately seems to be hampered by a lack of reproducibility. Variations in conductivity readings makes it very difficult, if not impossible, to define generally applicable diagnostic thresholds for discriminating among carious involvement. It may be hypothesized, that this problem is related to the very nature of the 2-point measurement configuration underlying all of the experimental methods, described in the literature as today. This study instead, aims to develop and evaluate a new method of spectroscopic Electrical Impedance Tomography (EIT), capable of reconstructing cross-sectional maps of the coronal tooth structure, depicting site-specific electrical impedance spectra. The resulting method promises to improve upon existing electrical caries detection methods, both in terms of its improved cross-sectional sampling strategy, dispensing with the need to rely on visual surface indications to determine appropriate measurement sites, and its immunity with regard to the natural variability in electrical conductance between individual teeth. Tomographic representation of the measurement results will allow the diagnostic interpretation to proceed on the basis of relative changes in tissue impedance among different spatial locations, instead of being dependent on a single quantitative interpretation. The suggested spectroscopic extension of the established method of EIT , together with the particularly difficult measurement conditions created by the insulating properties of the outer enamel layer, will pose some very specific problems as to the mathematical demands on the reconstruction algorithms. Therefore, the study and evaluation of non-linear reconstruction algorithms for the inverse conductivity problem of EIT, based on concepts drawn from numerical algebra, will constitute the major contribution in this research proposal. Despite the fact that evaluation of the algorithmic developments will be limited to numerical simulation and in vitro experiments, design of the newly developed method will be such, that its essential properties can be expected to transfer straightforwardly to the clinical setting. To gain a more fundamental understanding of the electrical conduction phenomena taking place in dental structures, a first, morphological accurate, numerical simulation model of a whole tooth will be built. The detailed morphological input data for this model will be derived from micro-Computed Tomography (micro-CT) scans, acquired with a microfocal desktop-sized measurement system. Cross-sectional images acquired in this way, will be processed by an automatic segmentation procedure, before being converted into a 3D Finite Element (FE) mesh. Such a mesh description allows to build up the actual volumetric simulation model.

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      • Research Project

      Towards exact measurings of physical parameters by means of model-based electron microscopy. 01/10/2003 - 30/09/2007

      Abstract

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      • Research Project

      Quantitative analysis of electron energy loss spectroscopy of nanostructures. 01/10/2003 - 30/09/2005

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      • Research Project

      Texture characterization of texture in digital images for automated recognition and classification of tumors in MRI images. 01/05/2003 - 30/04/2005

      Abstract

      This project studies new methods for texture feature extraction from digital images. We will emphasize the robustness of the features under influence of e.g. noise and illumination. In a first phase, these features will be used on publicly available image databases. In a second phase we will employ these techniques for the analysis of weak tissue tumors in NMR images.

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      • Research Project

      01/01/2003 - 31/12/2004

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      • Research Project

      01/11/2002 - 31/10/2004

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      • Research Project

      Development of improved techniques for the analysis of functional magnetic resonance data. 01/10/2002 - 30/09/2005

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      • Research Project

      01/10/2002 - 30/09/2004

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      • Research Project

      01/10/2002 - 30/09/2003

      Abstract

      Researcher(s)

      • Promoter: De Clerck Nora
      • Co-promoter: Van Dyck Dirk
      • Fellow: Postnov Andreï

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        • Research Project

        01/10/2002 - 30/09/2003

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          • Research Project

          01/10/2002 - 30/09/2003

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            • Research Project

            01/08/2002 - 31/07/2003

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              • Research Project

              01/05/2002 - 30/04/2004

              Abstract

              The goal of this project is the development of a robust method for characterization of 3D binary objects, applied to rough diamonds. In particular, we will focus on the development of an invariant multiscale representation of a object surfaces (manifolds). It is expected that, at least scientifically, a possible solution will be provided for the 'blood diamonds' problem.

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              • Research Project

              01/01/2002 - 31/12/2003

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              • Research Project

              01/01/2002 - 30/06/2002

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                • Research Project

                Contribution to the development of a novel method of spectroscopic electrical impedance tomography (EIT) with application to the assessment of hidden caries. 17/12/2001 - 17/12/2004

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                • Research Project

                Microstructure and nano-structured materials. 01/10/2001 - 30/09/2002

                Abstract

                The microstructure and nanostructure of thin film materials becomes more an more important with a reduction of the components. The idea is to correlate with the help of electron microscopy the local structure with the physical and chemical properties.

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                  • Research Project

                  The local structure of nano structured materials and thin film ceramic and semiconducting materials. 01/01/2001 - 31/12/2004

                  Abstract

                  The recent evolution from microtechnology to nanotechnology only increases the importance of transmission electron micrsocopy. The idea is to quantify not only the sub 0.2 nm high resolution electron microsocopy, but also the local energy electron loss spectra.

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                  • Research Project

                  01/01/2001 - 31/12/2002

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                    • Research Project

                    01/01/2001 - 31/12/2001

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                      • Research Project

                      01/10/2000 - 30/09/2002

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                        • Research Project

                        Recognition of a rough diamond by means of microtomography. 01/07/2000 - 31/12/2000

                        Abstract

                        The project consists of performing the research of recognizing a rough diamond via its external structure with the microtomographic technology and providing it with an individual code through an algorythm or other way of calculation if that may seem necessary.

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                          • Research Project

                          Mechanical integrity and architecture of bone relative to osteoporosis, ageing and drug treatment. (MIAB) 01/01/2000 - 31/12/2002

                          Abstract

                          Spatial and temporal changes of bone architecture will be measured by X-ray microtomography. Matching software will be developed. The long term aim of the proposed project is to establish how two types of osteoporosis (age related and oestrogen deficiency related) affect the ability of trabecular bone structures to support load.

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                            Structure determination of ceramic thin films by quantitative transmission electron microscopy. 01/01/2000 - 31/12/2001

                            Abstract

                            A study of the local atomic structure of ceramic thin films by quantitative TEM. A model for the electron-object interaction and the imaging process has unknown parameters; like the local atom positions, which can to be determined from the experiment with high precision using a criterium.

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                              • Research Project

                              Development of a Phase Contrast Aberroscope 01/01/2000 - 31/12/2001

                              Abstract

                              The principles of phase contrast microscopy are used to map the aberrations of the human eye's optical system. There are reasons to belief this will result in a very fast and accurate method to determine eye aberrations.

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                                • Research Project

                                01/01/2000 - 31/12/2000

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                                  • Research Project

                                  Integration of high-resolution MRI and micro-CT data. 01/10/1999 - 30/09/2001

                                  Abstract

                                  The main goal of this IWT-project is the development of a methodology to study an object with a high-resolution MRI and micro-CT system. This implies of course an optimization of the image information. Thus, a very important aspect of this project is the determination, optimization and comparison of the resolution of both imaging systems. Here the problem of resolution and reconstruction of CT and MRI will be studied with parameter estimation methods.

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                                    • Research Project

                                    Image processing for integrated and immersive visualisation. 01/07/1999 - 30/06/2001

                                    Abstract

                                    In this research we examine the fusion of images of an object into one image that will contain the information of its constituents. The component images come for different sources as a result of which the resolution can differ. Because of this the presented techniques based on multiscale representation are highly suitable.

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                                      • Research Project

                                      Functional MR Imaging (fMRI) of the cortex of the cerebellum of the rat. 01/05/1999 - 30/04/2001

                                      Abstract

                                      fMRI was up to now almost exclusively performed in human subjects and only few papers reveal the work done on small animals. This animal study exclusively deals with the brain cortex. However, the cerebellum has recently gained interest because it seems to have more functions than first expected. In the framework of this project we wish to study the tactile input projections to the cerebellum using fMRI.

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                                        • Research Project

                                        Monitoring the corrosion state of glass objects by optimized micro-computerised X-ray-tomography. 01/01/1999 - 31/12/2001

                                        Abstract

                                        The aim of the project is to introduce micro-computerised X-ray Tomography (mCT) as a new non-destructive tool for glass conservation. The main objectives are to demonstrate the potential of mCT for the improvement of the restoration and conservation techniques for archeological glasses. The project is situated in the Conservation of the European cultural heritage. mCT is probably the only nondestructive method to gain information about the internal morphology of such archeological fragments. Therefore the equipment must be improved and adapted for this purpose and model model glasses will be used to establish the procedure and to calibrate the analysis.

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                                          • Research Project

                                          Region of interest X-ray microtomography. 01/01/1999 - 31/07/2000

                                          Abstract

                                          The objective of this project is the development of an analytical method for Region of interest tomography. The purpose of Region of interest tomography is to use only local data for reconstructing a limited part of the object. Global filtering operations as used in standard tomographic reconstruction must thus be avoided. The method will be tested and implemented on an existing Skyscan X-ray microtomography system.

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                                            • Research Project

                                            X-ray phase contrast microtomography for the scanning of diamonds. 01/12/1998 - 30/11/2000

                                            Abstract

                                            The aim of this project is the development of an X-ray microtomograph for the localisation of defects (inclusions and cracks) in rough diamond. Therefore, the more sensitive phase contrast method will be used instead of the classical absorption contrast method. The most important difficulty is performing phase contrast measurements using a polychromatic X-ray source. A state of the art X-ray source and detector will be necessary.

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                                              • Research Project

                                              3D source-localization through an integrated processing of simultaneously obtained EEG and fMRI data. 01/11/1998 - 31/10/2000

                                              Abstract

                                              This project deals with the processing of simulteneously acquired EEG and fMRI data as to obtain an accurate localization of epileptic brain activity. The research will focuss on the reduction of MR related artefacts in EEG data and vice versa, on image processing of magnitude MR data and on the modification of the MR imaging sequence after EEG data processing.

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                                                • Research Project

                                                High resolution functional magnetic resonance imaging (fMRI) and image analysis on a model system in the rat: localisation of facial tactile input-projections in the cerebellum 01/10/1998 - 30/09/2000

                                                Abstract

                                                Implementation and optimalization of high resolution fMRI and image analysis on a 7 Tesla machine, using different acquisition and processing techniques, with the aim of achieving a high spatial as well as temporal resolution.

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                                                  Implementation of quantitative structure determination methods on the 1 Angström electron microscope in EMAT. 01/10/1998 - 31/03/1999

                                                  Abstract

                                                  During his research-stay, dr. Thust will implement and optimize the reconstruction and alignment algorithms that he himself has developed, onto the advanced 1 Angström electron microscope at the research group EMAT.

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                                                    Generic optimalisation. 01/01/1998 - 31/12/2001

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                                                      • Research Project

                                                      Image restoration of Magnetic Resonance Images 01/05/1997 - 30/04/1999

                                                      Abstract

                                                      The purpose of this project is the improvement of spatial resolution in the field of Magnetic Resonance Imaging. The system PSF will be determined theoretically and experimentally. This knowledge will be used in the optimalisation of a Fourier reconstruction scheme.

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                                                        • Research Project

                                                        Functional Magnetic Resonance Imaging (fMRI) of the cerebellar cortex of the rat 01/05/1997 - 30/04/1999

                                                        Abstract

                                                        fMRI was up to now almost exclusively performed on human subjects and very ew data exist on animals. Although the cerebellum is far more frequently activated that expected and therefore very interesting as a study object, fMRI was so far restricted to the cerebral cortex. We want to investigate the distribution of tactile inputs at the level of the upper lip of the rat in the cerebellar cortex of the rat. This will contribute to the unraveling of the underling mechanisms of cerebellar functioning.

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                                                          Unsupervised pattern recognition: feature reduction and classification 01/10/1996 - 30/09/1998

                                                          Abstract

                                                          High-dimensional data spaces with a low number of data points are hard to classify. The introduction of artificial neural networks can change this. This project investigates the possibilities of non-linear dimensionality reduction and clustering.

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                                                            High resolution functional magnetic resonance imaging (fMRI) and image analysis on a model system in the rat: localisation of facial tactile input-projections in the cerebellum 01/10/1996 - 30/09/1998

                                                            Abstract

                                                            Implementation and optimalization of high resolution fMRI and image analysis on a 7 Tesla machine, using different acquisition and processing techniques, with the aim of achieving a high spatial as well as temporal resolution.

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                                                              Proximity correction in electron beam lithography. 01/06/1996 - 31/05/1997

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                                                                Image simulation and image processing in electron microscopy. 01/05/1996 - 30/04/1998

                                                                Abstract

                                                                With the introduction of a new and more coherent type of electron source it will be possible in the future to enhance the resolution in electron microscopy by means of image processing unto the atomic level. Hereto new methods are developed and tested on simulated and experimental image series. This work requires also a refinement of the existing image simulation packages in order to make them more congruent with the experimental reality.

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                                                                  • Research Project

                                                                  Image processing systems. 01/01/1996 - 31/12/2000

                                                                  Abstract

                                                                  The main goal of this network is the exchange of information between four domains of research (i.e. image processing, electronic/optical system design, computer architectures and communication) and different application domains (e.g. document processing, compression and analysis of satellite images, medical image processing, HDTV, videophony, ISDN image transmission, industrial visual inspection, robot vision, image generation ...). The main objective of the research community is to create a framework for structural co-operation in Flanders, in collaboration with existing European network activities

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                                                                    Improvement and application of high resolution electron microscopy techniques to the study of materials. 01/01/1996 - 31/12/1999

                                                                    Abstract

                                                                    1) Order-disorder phenomena in metallic alloys - Martensitic transformations; 2) Structure of and defects in ceramic materials; 3) Super-ionconductors; 4) Modulated incommensurable structures; 5) Phase transitions; 6) Characterization of separation surfaces between solid phases.

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                                                                      01/01/1996 - 31/12/1997

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                                                                        01/01/1996 - 31/12/1996

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                                                                          Study of the physiology and physiopathology of the human vestibulo-ocular reflex using video-oculagraphic registration of the torsional, horizontal and vertical eye movements 30/09/1995 - 31/12/1999

                                                                          Abstract

                                                                          The quantification of the vestibulo-ocular reflex with a normative study by stimulating the vestibular organ with linear and rotational accelerations in the horizontal and vertical plane. Investigation of the influence of selective peripheral and central lesions on the vestibulo-ocular reflex during provocations in the different directions.

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                                                                            Evaluation of the clinical relevance of the investigation of the three dimensional vestibulo ocular reflex (3D VOR) in specific neurological lesions and in the genetic research of autosomal dominant hearing loss. 30/09/1995 - 31/12/1999

                                                                            Abstract

                                                                            Horizontal, vertical and torsional vestibulo-ocular reflexes (3D VOR) are mediated by the central vestibular neurological pathways. With computer video analysis techniques vertical, horizontal and torsional eye movements can be analysed simultaneously and on line in a clinical setting. Norrnative data will be obtained for these reflexes in respons to jaw, role and pitch stimulations. Analysis of this 3-D VOR and correlating them with specific neurological system involvements and genetic deafness will enable to eva luate the additional clinical value of this investigation.

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                                                                              Integration, management and processing of images for high-end applications. 01/09/1995 - 31/08/1998

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                                                                                Intelmic - 3D : Intelligent microscope for 3D characterisation of microcrystal populations via neural networks 01/09/1995 - 31/08/1997

                                                                                Abstract

                                                                                Using light microscopy micro crystal populations are investigated for their shape and thickness. The thickness is found using colour information in reflection, the shape can be found by classification procedures. The aim is a fully automatic characterisation.

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                                                                                  Tele-diagnostics of x-ray images as application of video-conferencing. 01/01/1995 - 31/12/1996

                                                                                  Abstract

                                                                                  A system for tele-diagnose will be implemented. It will allow medical experts via video-conferencing to reach a common opinion based on images present at all participating sites. The experimental setup will be used to try out new algorithms in an operational context.

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                                                                                    Hoge resolutie elektronenmicroscopie van de atomaire structuur van kristallijne materialen. 01/05/1994 - 30/04/1996

                                                                                    Abstract

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                                                                                    • Promoter: Van Dyck Dirk
                                                                                    • Co-promoter: Van Camp Peter
                                                                                    • Co-promoter: Van Ocken Eric

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                                                                                      Telediagnosis of X-ray images as an application of videoconferencing. 01/01/1994 - 31/12/1996

                                                                                      Abstract

                                                                                      The aim is to perform computer aided diagnosis of digital mammographs. Classical image processing techniques are combined with artificial neual networks. The diagnosis system is combined with a videoconferencing system to allow for cooperative working.

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                                                                                        01/01/1994 - 31/12/1996

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                                                                                          01/01/1994 - 31/12/1994

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                                                                                            Vision. 30/09/1993 - 31/12/1997

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                                                                                              Image recognition by adaptive signal processing. 01/09/1993 - 31/08/1994

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                                                                                                High resolution electron microscopy of structures and defects of solid state materials. 01/01/1993 - 31/12/1994

                                                                                                Abstract

                                                                                                Study of high resolution techniques for their application in the analysis and characterisation of materials, their structure, defects and their physical behaviour upon thermal treatment. Interpretation theories and the development of algorithms and procedures for improving the instrumental capabilities also belong to the programme. These techniques will be applied for studies of materials such as semiconductor elements for microelectronics, alloys, ceramic materials, and other inorganic compounds.

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                                                                                                  30/09/1992 - 29/09/1994

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                                                                                                    30/09/1992 - 29/09/1994

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                                                                                                      30/09/1992 - 29/09/1993

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                                                                                                        • Research Project

                                                                                                        30/09/1991 - 29/09/1995

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                                                                                                          Automatization in design and production - Robotvision: restoration and formal scanning. 01/01/1990 - 31/12/1996

                                                                                                          Abstract

                                                                                                          The automatisation of complex processes, upon which are made high demands as regards precision, speed and flexibility, is the propellor behind the evolution towards powerful robotsystems, which can adapt to severe environmental changes and which have a high degree of autonomy in executing non-completely defined tasks in non-completely structured environments. Integration of sensor-information about the environment in the robotsteering and the development of high-level computer languages for sensor-steered robots are the pivot of this evolution. This research aims at the improvement and acceleration of the interpretation of visual information (a.o. through CAD-models) by relying as well on a nominal geometric model of the environment.

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                                                                                                            Sub-ångström structure characterisation: a new technology for direct structure determination based on holography and focus variation with a computerized field emission transmission electron microscope. 01/01/1990 - 31/01/1994

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