Structure-property investigation of new "KetoFAPI" inhibitors of fibroblast activation protein (FAP) : discovery of highly potent, selective compounds with prolonged residence times and promising radiotheranostic potential

Source
Journal of medicinal chemistry - ISSN 0022-2623-68:20 (2025) p. 21739-21765

Intercellular interaction between FAP+ fibroblasts and CD150+ inflammatory monocytes mediates fibro-stenosis in Crohn’s disease

Source
The journal of clinical investigation - ISSN 1558-8238-134:16 (2024) p. 1-19
Author(s)
    Bo-Jun Ke, Saeed Abdurahiman, Francesca Biscu, Gaia Zanella, Gabriele Dragoni, Sneha Santhosh, Veronica De Simone, Anissa Zouzaf, Lies van Baarle, Michelle Stakenborg, Veronika Bosáková, Yentl Van Rymenant, Emile Verhulst, Sare Verstockt, Elliott Klein, Gabriele Bislenghi, Albert M. Wolthuis, Jan Frič, Christine Breynaert, Andre D'Hoore, Pieter van der Veken, Ingrid De Meester, Sara Lovisa, Lukas J.A.C. Hawinkels, Bram Verstockt, Gert De Hertogh, Séverine Vermeire, Gianluca Matteoli