Development of biochemical assays to enable FAP-targeted inhibitor discovery and cancer biomarker applications

Source
Antwerp, University of Antwerp, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Department of Pharmaceutical Sciences, 2026,XVII, 330 p.

In vitro kinetic profiling by enzymatic approaches to select FAPIs with a long residence time

Selective and orally bioavailable dipeptidyl peptidase 9 inhibitors with potent pyroptosis induction properties

Source
Journal of medicinal chemistry - ISSN 0022-2623-68:21 (2025) p. 23163-23184
Author(s)

Structure-property investigation of new "KetoFAPI" inhibitors of fibroblast activation protein (FAP) : discovery of highly potent, selective compounds with prolonged residence times and promising radiotheranostic potential

Source
Journal of medicinal chemistry - ISSN 0022-2623-68:20 (2025) p. 21739-21765