Research team
Identification of biomarkers using proteomics to detect cervical cancer.
Abstract
Cervical cancer is caused by the human papillomavirus (mostly by "high risk" HPV-types 16, 18, 31, 45 en 58) and is worldwide the second most frequent cancer among females. Screening (using the classical "Papanicolaou smear") is based on the detection of morphological changes but is characterized by a low sensitivity. Therefore, the aim of this PhD project will be the identification of biomarkers using cervical vaginal fluid (CVF), by means of proteome analytical techniques, to detect premalignant cervical lesions. Due to the complex composition of the CVF, samples (lavages or swabs) will be separate by using multi-dimensional chromatography and will be characterized by the application of differential mass spectrometry.Researcher(s)
- Promoter: Van Ostade Xaveer
- Fellow: Van Raemdonck Geert
Research team(s)
Project type(s)
- Research Project
Identification of biomarkers using proteomics to detect cervical cancer.
Abstract
Cervical cancer is caused by the human papillomavirus (mostly by "high risk" HPV-types 16, 18, 31, 45 en 58) and is worldwide the second most frequent cancer among females. Screening (using the classical "Papanicolaou smear") is based on the detection of morphological changes but is characterized by a low sensitivity. Therefore, the aim of this PhD project will be the identification of biomarkers using cervical vaginal fluid (CVF), by means of proteome analytical techniques, to detect premalignant cervical lesions. Due to the complex composition of the CVF, samples (lavages or swabs) will be separate by using multi-dimensional chromatography and will be characterized by the application of differential mass spectrometry.Researcher(s)
- Promoter: Van Ostade Xaveer
- Fellow: Van Raemdonck Geert
Research team(s)
Project type(s)
- Research Project