Research team
Expertise
Structural research of organic molecules by means of mass spectrometric techniques and organic chemical analysis of atmospheric aerosols.
Levoglucosan analyses 2011-2012.
Abstract
This project represents a formal research agreement between UA and on the other hand VMM. UA provides VMM research results mentioned in the title of the project under the conditions as stipulated in this contract.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- VL. INST.
Project type(s)
- Research Project
EC/OC analyses 2011-2012.
Abstract
This project represents a formal research agreement between UA and on the other hand VMM. UA provides VMM research results mentioned in the title of the project under the conditions as stipulated in this contract.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- VL. INST.
Project type(s)
- Research Project
Secondary organic aerosol from isoprene: smog chamber studies, development of analytical methodology for isoprene organosulfates, and application to ambient fine forest aerosol (postdoc. W. WANG, China).
Abstract
This project represents a formal research agreement between UA and on the other hand the Federal Public Service. UA provides the Federal Public Service research results mentioned in the title of the project under the conditions as stipulated in this contract.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- BELSPO
Project type(s)
- Research Project
Secondary organic aerosol formation from monoterpenes: gaps in our current understanding.
Abstract
The major objectives of the project are to unravel the role of terpenylic acid and related compounds. We hypothesize that these compounds are key monomers of the clusters formed in the early stages of new particle formation, as well as of polar and higher-molecular weight (MW) products formed upon chemical aging, owing to the reactivity of the lactone group.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Co-promoter: Van Der Veken Pieter
Funding
- FWO
Project type(s)
- Research Project
Biogenic influences on oxidants and secondary organic aerosol: theoretical, laboratory and modelling investigations (BIOSOA).
Abstract
In this project, we propose an integrated approach consisting of laboratory, theoretical and modelling investigations aiming to better understand and quantify the role of biogenic hydrocarbons, in particular with respect to the formation of ozone and aerosols and the oxidation capacity of the atmosphere. This project aims to provide a better scientific basis for decision-making (especially at an international level) with regard to anthropogenic emissions of pollutants like the nitrogen oxides, volatile organic compounds and fine particulate matter.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Co-promoter: Maenhaut Willy
Funding
- BELSPO
Project type(s)
- Research Project
Chemical characterization of particulate matter - EC/OC analysis 2010.
Abstract
This project represents a formal research agreement between UA and on the other hand VMM. UA provides VMM research results mentioned in the title of the project under the conditions as stipulated in this contract.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- VL. INST.
Project type(s)
- Research Project
Chemical characterisation of fine particles - Levoglucosan analyses 2010.
Abstract
This project represents a formal research agreement between UA and on the other hand VMM. UA provides VMM research results mentioned in the title of the project under the conditions as stipulated in this contract.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- VL. INST.
Project type(s)
- Research Project
SOAMASS - Characterization of secondary organic aerosol from photooxidation of isoprene and alpha-pinene with mass spectrometric approaches.
Abstract
Characterization of secondary organic aerosol from photooxidation of isoprene and alpha-pinene with mass spectrometric approaches.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- EU-KADER
Project type(s)
- Research Project
Biogenic and bioaerosol formation from terrestrial vegetation.
Abstract
The relationship will be studied between reactive volatile organic compounds, which are emitted by the vegetation or anthropogenic sources and are photo-oxidized in the atmosphere, and organic aerosol formation. In addition, the contribution of bioaerosols to the organic aerosol load will be assessed. The experiments will be conducted in plant growth chambers and a mixed pine-oak forest.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Co-promoter: Janssens Ivan
Funding
- BOF
Project type(s)
- Research Project
Characterization of biologically active plant metabolites and carbonaceous aerosols using mass spectrometric methods.
Abstract
This project concerns structural investigation research on biologically active plant metabolites and carbonaceous aerosols using mass spectrometric methodology based on a soft ionization technique, i.e. electrospray ionization (ESI), in combination with collision-induced dissociation (CID) and tandem mass spectrometric (MS/MS) techniques. Methods will be developed for the determination of the strength of non-covalent drug-haem interactions and for the characterization of plant metabolites in crude extracts with potential antimalarial activity, as well as for the structural characterization of biologically active plant metabolites that will be isolated from medicinal plants and of polar organic molecules in carbonaceous aerosols that are formed through photo-oxidation of isoprene. This project deals with : 1) investigation of the non-covalent interaction between plant metabolites with the potential antiplasmodial activity and haem; 2) structural characterization of unknown biologically active plant metabolites isolated from medicinal plants; 3) structural characterization of oxidation products of isoprene in smog chamber and natural biogenic aerosols.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Co-promoter: Pieters Luc
Funding
- FWO
Project type(s)
- Research Project
The importance of volatile organic compounds in the carbon budget of terrestrial ecosystems and in the formation of secundary organic aerosols.
Abstract
In this project, we intend to study the importance of VOC emissions both in the total carbon budget of terrestrial ecosystems (objective 1) and the importance of specific VOC's in the formation of secondary organic aerosols (objective 2). Objective 1 will be realized by incorporating an existing mechanistic VOC model into a mechanistic SVAT model and by direct VOC-flux measurements using PTR-MS and either chambers of disjunct eddy covariance. Objective 2 will be achieved by chemical characterization of the organic aerosols and its comparison with the spectrum of the emitted VOC's.Researcher(s)
- Promoter: Janssens Ivan
- Co-promoter: Claeys-Maenhaut Magda
Research team(s)
Funding
- FWO
Project type(s)
- Research Project
Formation mechanisms, marker compounds, and source apportionment for biogenic atmospheric aerosols. (BIOSOL)
Coronary hemodynamics after a myocardial infarction.
Abstract
Cardiovascular morbidity and mortality is one of the major health issues in the Western world. It is known that myocardial infarction can severely affect the prognosis of a patient. More research in this area is needed. Miniaturisation of the technology has made it possible to perform measurements in the human coronary circulation. This technological development offers an unique opportunity to study pathophysiological processes in humans. The vasoreactivity of the microcirculation can for instance be assessed by measuring the flow in basal and hyperemic conditions. Furthermore it is possible to perform simultaneous pressure-flow measurements. With the use of adapted software these signals can be combined and a pressure-flow loop of the coronary circulation can be made. Extrapolation of the diastolic pressure-flowrelation to the pressure-axis (X-axis) can give us an estimation of the zero flow pressure. The slope of this diastolic relation can also learn us something about the conductance of the coronary circulation. Nowadays one has realised that myocardial infarction triggers an inflammatory cascade which is accompanied by the release of numerous cytokines. Their prognostic implications can no longer be denied. The mechanisms that relate acute phase proteins to short and long term prognosis are unclear. New data suggest that impairment of the endothelial function by an inflammatory response creates a link between systemic inflammation and ischemic coronary syndromes. The purpose of this project is to gain more insight in the pathophysiology of the coronary circulation after infarction by perfoming intracoronary measurements and by measuring inflammatory cytokines.Researcher(s)
- Promoter: Vrints Christiaan
- Co-promoter: Bosmans Johan
- Co-promoter: Claeys-Maenhaut Magda
- Fellow: Van Herck Paul
Funding
- FWO
- BOF
Project type(s)
- Research Project
OOMPH - Organics over the ocean modifying particles in both hemispheres.
Characterization of oxidation products of isoprene in biogenic rural aerosols. (R. SZMIGIELSKI, Polen)
Support maintenance scientific equipment (Bio-organic mass spectrometry).
Abstract
Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- BELSPO
- BOF
- BOF
Project type(s)
- Research Project
Carbonaceous aerosol characterisation of rural background aerosols from Europe. (Alina ION, Roemenië)
Abstract
Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Ion Alina
Funding
- BELSPO
Project type(s)
- Research Project
Urban and rural carbonaceous aerosols in Flanders and Hungary : characterisation, source identification and apportionment, and chemical mass closure.
Investigation of non-covalent complex formation between haem and antimalarial drugs by mass spectrometric approaches.
Abstract
Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Pashynska Vlada
Funding
- BOF
Project type(s)
- Research Project
Development and application of LC/MS and MS/MS methods for the structural characterisation of flavonoid glycosides.
Abstract
In this doctoral research project a LC/MS method will first be developed: to this aim a HPLC system with photodiode array detection will be connected to the electrospray ionisation source of the Autospec-oa-TOF mass spectrometer. In a second phase several MS/MS methods based on high- and low-energy collision-induced dissociation of protonated and deprotonated molecules will be evaluated for the structural characterisation of flavonoid glycosides.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Cuyckens Filip
Funding
- IWT
Project type(s)
- Research Project
Smoke aerosols, clouds, rainfall and climate : aerosols from biomass burning perturb global and regional climate (SMOCC).
Abstract
The overall goal of the project is to investigate the connection between the abundance of biomass burning aerosol, the lowering of the size of cloud droplets formed on this aerosol, and the climatic consequences of the resulting perturbation of cloud physics. Our contribution to this project relates to the chemical characterization of biomass burning aerosols, in particular the organic fraction.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- EU-KADER
Project type(s)
- Research Project
Development of analytical methods for the determination of water-soluble organic compounds in fine atmospheric aerosols.
Abstract
The analytical methodology to be developed involves fractionation of the water-soluble organic compounds into three main classes of compounds using anion exchange chroma- tography. The contribution of each fraction to the organic carbon mass will be determined. Compounds representative of each class will be characterized using mass spectral approaches. The methodology will be applied to urban aerosols from Belgium and Italy.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- VL.WET.BEL
Project type(s)
- Research Project
Development of analytical methods for carbonaceous aerosol characterization based on ion trap gas chromatography/mass spectrometry and electrospray ionization - mass spectrometry. Application to biomass burning aerosols. (Vlada PASHYNKA)
Abstract
This project deals with the development of analytical methods for carbonaceous atmospheric aerosols, more specifically, of: (1) a method for the determination of levoglucosan and related compounds using ione trap gas chromatography/mass spectrometry, and (2) a method for the characterization of humic acid-like substances using electrospray ionization mass spectrometry, and application of the developed methods to biomass burning aerosols.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Pashynska Vlada
Funding
- BELSPO
Project type(s)
- Research Project
Characterization and sources of carbonaceous atmospheric aerosols
Abstract
The objectives of the project are to better characterize the fine size fraction (aerodynamic diameter < 2 ?m) of atmospheric aerosols which is relevant to climate and the health of humans and animals. Emphasis will be placed on: 1. detailed characterization of organic compounds containing acidic groups; 2. development of methodology for the determination of water soluble compounds, including levoglucosan and humic-like substances; and 3. determination of marker compounds for atmopheric oxidation and biomass burning processesResearcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- BELSPO
Project type(s)
- Research Project
Development of mass spectrometric methods for the determination of polar organic compounds in atmospheric aerosols with special emphasis on dicarboxylic acids and humic-like substances.
Abstract
This project involves: (1) the evaluation and development of micro-analytical methods for the determination of dicarboxylic acids and humic-like substances in atmospheric aerosols, and (2) the application of the developed methods to urban and tropical aerosols.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Jeko J Ozsef
Funding
- BELSPO
Project type(s)
- Research Project
Biomedical applications of organic mass spectrometry.
Abstract
High performance organic mass spectrometry is applied to the structural characterization of complex biomolecules such as neuropeptides, acylcarnitines, nucleosides and biologically active plant metabolites. The mass spectral techniques used include hybrid tandem mass spectrometry, electron impact and fast atom bombardment ionization and high resolution.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Claeys-Maenhaut Magda
Funding
- BOF
Project type(s)
- Research Project
Abstract
Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Voinov Valery
Funding
- BOF
Project type(s)
- Research Project
Physicochemical characterization of tropospheric aerosols with emphasis on fine secondary and organic aerosols. (FWO Vis.Fel.)
Abstract
The objectives of the project are to better characterize the fine size fraction (aerodynamic diameter < 2 ?m) of tropical atmospheric aerosols which is relevant to climate. Emphasis will be placed on: 1. detailed characterization of organic compounds containing carbonyl groups; 2. development of methodology for the determination of polar neutral compounds, including levoglucosan; and 3. determination of marker compounds for atmopheric oxidation and biomass burning process.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Zdrahal Zbynek
Funding
- FWO
Project type(s)
- Research Project
Development of methods for the determination of semi-volatile organic compounds in athmospheric aerosols with special emphasis on dicarboxylic acids.
Abstract
This project involves: (1) development of a solid phase extraction technique for the characterization of water-soluble organics, and, more in particular, of dicarboxylic acids, and (2) application of developed methods to tropical atmospheric aerosolsResearcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Zdrahal Zbynek
Funding
- BELSPO
Project type(s)
- Research Project
Development and application of LC/MS and MS/MS methods for the structural characterisation of flavonoid glycosides.
Abstract
In this doctoral research project a LC/MS method will first be developed: to this aim a HPLC system with photodiode array detection will be connected to the electrospray ionisation source of the Autospec-oa-TOF mass spectrometer. In a second phase several MS/MS methods based on high- and low-energy collision-induced dissociation of protonated and deprotonated molecules will be evaluated for the structural characterisation of flavonoid glycosides.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Cuyckens Filip
Funding
- IWT
Project type(s)
- Research Project
Determination of organic compounds in atmospheric aerosols using gas chromatography.
Abstract
The project involves: (1) the development of gas chromatography/mass spectrometry methods for the characterization of organic compounds, more specifically dicarboxylic acids which can be regarded as markers for atmospheric oxidation processes, and (2) application of the methods to tropical aerosols.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Kubatova Alena
Funding
- BOF
Project type(s)
- Research Project
Multidisciplinary spectroscopic research of organic materials and biomolecules.
Abstract
In the proposed concerted action fundamental properties of synthetic organic compounds and biomolecules will be studied, giving emphasis to the study of their molecular and electronic structure with the aid of the following spectroscopic methods: electron spin resonance (ESR), mass spectrometry (MS), nuclear magnetic resonance (NMR) and vibration spectroscopy (IR-absorption and Raman diffraction). The research team includes four laboratories with state-of-the-art instrumentation and internationally recognized expertise with regard to the above mentioned spectroscopic methods, and two associated laboratories which are active in a complementary way in the preparation and evaluation of the materials studied. The research will focus on two classes of materials: (i) Biomolecules, more specifically, carbohydrate, lipid-like and polyphenolic compounds. These biomolecules show in general a high natural complexity with regard to their structure as well as their function. They show a broad range of biological activities, have already resulted in useful pharmaceuticals and are still important in the development of the latter. Some of these biomolecules enjoy a current interest with regard to prevention against degenerative diseases and cancer. (ii) Aromatic oligomers and polymers with electrical and optical applications. Some technologically relevant examples are conducting polymers, - with chemical detectors as a specific application -, and polymeric light-emitting diodes (LED's). In the synthesis of these materials a large variation of compounds can be prepared and in some cases structure determination of the molecules is desirable. In addition, the determination and engineering of electronic and other functional properties is important for the applicability of the materials.Researcher(s)
- Promoter: Goovaerts Etienne
- Co-promoter: Claeys-Maenhaut Magda
- Co-promoter: Dommisse Roger
- Co-promoter: Van Der Veken Benjamin
Funding
- BOF
Project type(s)
- Research Project
Characterisation of the organic fraction of tropical atmospheric aerosols by mass spectrometry.
Abstract
This project involves: (1) development of a mass spectrometric method for the characterisation of fatty acids based on resonance electron capture ionisation; and (2) characterisation of the organic fraction, more in particular, the organic acids, by means of gas chromatography-mass spectrometry.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- BELSPO
Project type(s)
- Research Project
Investigation of charge-remote fragmentation in n-alkyltriphenylphosphonium cations observed at high-energy collision-induced dissociation tandem mass spectrometry.
Abstract
n-Alkyltriphenylphosphonium cations give rise to the elimination of n-alkenes and molecular hydrogen upon high-energy collision-induced dissociation without an obvious involvement of the charge. The objective of the project is to investigate the fragmentation mechanism of these even-electron ions using deuterium labelling and tandem mass spectrometric techniques.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- FWO
Project type(s)
- Research Project
Mass spectrometric structure characterisation of biomolecules and functional dyes: study of ionisation and fragmentation mechanisms, development of methods and analytical applications.
Abstract
The proposed research programme deals with mass spectrometric studies on the structural characterisation of biomolecules which will remain of fundamental biological interest and of functional dyes which are important for their material properties. The molecules which will be studied include lipide, plant glycoconjugates, peptides, proteins and aromatic oligomers and polymers. The objectives are to examine in detail and systematically the unimolecular chemistry of some of these compounds in the gas phase.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Co-promoter: Geise Herman
- Co-promoter: Haemers Achiel
- Co-promoter: Pieters Luc
- Co-promoter: Vlietinck Arnold
Funding
- FWO
Project type(s)
- Research Project
Physicochemical characterization, source identification, and transboundary transport of atmospheric aerosols over southern Africa.
Abstract
This multidisciplinary project involves: (a) method development for collection and chemical analysis of aerosols; (b) studies of the physicochemical properties of aerosols; and (c) reconstitution of the particulate mass, source type and source region identification, and assessment of the major transport pathways.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- VL.WET.BEL
Project type(s)
- Research Project
Sources, physichemical characteristics and climate "forcing" of atmospheric aerosols.
Abstract
The objectives of the proposed postdoctoral research are to achieve a detailed characterization of the organic fraction of climatologically active aÙrosols by the use of mass spectrometric methods, including differentiation between natural and anthropogenic contributions.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- BELSPO
Project type(s)
- Research Project
Mass spectrometric structure characterization of fatty acid derivatives: study of ionization and fragmentation mechanisms, development of methods and analytical applications.
Abstract
The proposed doctoral research programme involves: a study dealing with FAB ionisation phenomena of saturated fatty acid derivatives; a study dealing with the mechanism of charge-remote fragmentation which occurs when fatty acid derivatives with a stable charge are collisionally activated; and bioanalytical applications.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Huysmans Lennie H C M
Funding
- BOF
Project type(s)
- Research Project
Mass spectrometric structure determination of biomolecules. Analytical developments and bio-analytical applications.
Abstract
Mass spectral methodology will be developed for the structural analysis of nucleotides, oligonucleotides, peptides and proteins. The methodology involves the combined use of ionization by electrospray or fast atom bombardment, collisionally induced dissociation and tandem mass spectrometry.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Co-promoter: Moens Luc
- Co-promoter: Van Onckelen Harry
Funding
- FWO
Project type(s)
- Research Project
Sources, physicochemical characteristics and climate forcing of atmospheric aerosols.
Abstract
The objectives of the project are to characterize the organic fraction of climatologically active aerosols in order to obtain a more complete characterization of the mass or mass "closure". Semi polar organics will be determined qualitatively and quantitatively using capillary GC/FID and GC/MS methodology. Focus will be given to the differentiation between natural and anthropogenic contributions.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- BELSPO
Project type(s)
- Research Project
Mass spectrometric structure determination of biomolecules. Analytical developments and bio-analytical applications.
Abstract
Mass spectral methodology will be developed for the structural analysis of nucleotides, oligonucleotides, peptides and proteins. The methodology involves the combined use of ionization by electrospray or fast atom bombardment, collisionally induced dissociation and tandem mass spectrometry.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Co-promoter: De Potter Werner P L
- Co-promoter: Moens Luc
Funding
- FWO
Project type(s)
- Research Project
Biomedical applications of organic mass spectrometry.
Abstract
High performance organic mass spectrometry is applied to the structural characterization of complex biomolecules such as neuropeptides, acylcarnitines, nucleosides and biologically active plant metabolites. The mass spectral techniques used include hybrid tandem mass spectrometry, electron impact and fast atom bombardment ionization and high resolution.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Claeys-Maenhaut Magda
Funding
- FWO
Project type(s)
- Research Project
Peptide and protein structure elucidation by mass spectrometry. Analytical development and bioanalytical application.
Abstract
The recent development of desporption/ionization MS methods have been succesfully introduced to the direct analysis of peptides and proteins, which enable direct molecular weight determinations and structure characterization. Importants goals : (i) implementing these techniques for specific bio-analytical problems (2) develop training programs for young European researchers (3) further evaluation of the application potential of MS to protein-structure characterization.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- VL.WET.BEL
Project type(s)
- Research Project
Metabolism of w-3-docosahexaenoic acid containing molecular species of phospholipids by chromatography and tandem mass spectrometry.
Abstract
The project involves the isolation and the detailed characterization of w3-w-3-docosahexaenoic acid containing phosholipids in biological material (calf brain and fish liver) with a view to their therapeutic use.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- FWO
Project type(s)
- Research Project
Peptide and protein structure elucidation by mass spectrometry. Analytical development and bioanalytical application.
Abstract
The recent development of desporption/ionization MS methods have been succesfully introduced to the direct analysis of peptides and proteins, which enable direct molecular weight determinations and structure characterization. Importants goals : (i) implementing these techniques for specific bio-analytical problems (2) develop training programs for young European researchers (3) further evaluation of the application potential of MS to protein-structure characterization.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- EU-KADER
Project type(s)
- Research Project
Mass spectrometric structure determination of biomolecules. Analytical developments and bio-analytical applications.
Abstract
Mass spectral methodology will be developed for the structural analysis of nucleotides, oligonucleotides, peptides and proteins. The methodology involves the combined use of ionization by electrospray or fast atom bombardment, collisionally induced dissociation and tandem mass spectrometry.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Co-promoter: Slegers Herman
- Co-promoter: Van Onckelen Harry
Funding
- FWO
Project type(s)
- Research Project
Mass spectral characterization of neuropeptides and organic dyes
Abstract
High performance mass spectroscopy is applied to the structural characterization of complex biomolecules such as neuropeptides and organic dyestuffs used in photographic films. The mass spectral techniques used include hybrid tandem mass spectrometry, fast atom bombardment and collision induced dissociation.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- IWT
Project type(s)
- Research Project
CHaracterization of neuropeptides in chromaffin cells.
Abstract
Biologically active neuropeptides will be isolated from chromaffin granules using bioassay-guided fractionation. After isolation the biopeptides will be characterized using mass spectrometric methods.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Dillen Lieve
Funding
- FWO
Project type(s)
- Research Project
Mass spectral characterization of neuropeptides and organic dyes
Abstract
High performance mass spectroscopy is applied to the structural characterization of complex biomolecules such as neuropeptides and organic dyestuffs used in photographic films. The mass spectral techniques used include hybrid tandem mass spectrometry, fast atom bombardment and collision induced dissociation.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
Funding
- IWT
Project type(s)
- Research Project
Biomedical applications of organic mass spectrometry.
Abstract
High performance organic mass spectrometry is applied to the structural characterization of complex biomolecules such as neuropeptides, acylcarnitines, nucleosides and biologically active plant metabolites. The mass spectral techniques used include hybrid tandem mass spectrometry, electron impact and fast atom bombardment ionization and high resolution.Researcher(s)
- Promoter: Claeys-Maenhaut Magda
- Fellow: Claeys-Maenhaut Magda
Funding
- FWO
Project type(s)
- Research Project