Mayli investigates ways in which sense-making — through human and artificial cognition — shapes the physical world and how feedback loops affect such processes. Reflexive predictions like self-fulfilling and self-defeating prophecies are central to her work. Mayli was awarded the Marie Curie Postdoctoral Fellowship, for which she investigates the epistemic and ethical implications of predictions in genetics. Her main scientific interest is in epistemology and bioethics. In 2023, she founded the Atlas Center for Bioethics in Andalusia, in collaboration with the universities of Granada and Almeria.