No phenotypic resistance observed for most group-3 and-4 variants in Mycobacterium tuberculosis genes related to bedaquiline, clofazimine, delamanid, and pretomanid in a Central and West African context

Source
Microbiology spectrum - ISSN 2165-0497- (2026) p.
Author(s)
    Faridath Massou, Klaas Dewaele, Anderson Gnamy, Ramata Balde, Wim Mulders, Conor J. Mehan, Bouke De Jong, Dissou Affolabi, Oren Tzfadia, Leen Rigouts

Frameshift mutations in the mmpR5 gene can have a bedaquiline-susceptible phenotype by retaining a protein structure and function similar to wild-type Mycobacterium tuberculosis

Source
Antimicrobial agents and chemotherapy - ISSN 0066-4804-68:12 (2024) p. 1-15
Author(s)