LRRC59 cooperates with nuclear transporters to restrain the nuclear envelope repair machinery and safeguard genome integrity

Source
Nature communications - ISSN 2041-1723
Author(s)
    Romy Timmer, Aurélie Bellanger, Sarah Peeters, Hera Kim, Laura Rodriguez de la Ballina, Sissel Eikvar, Annemijn J. Arns, Esmée Oortgijs, Nikolina Sekulić, Winnok De Vos, Coen Campsteijn

Selective and orally bioavailable dipeptidyl peptidase 9 inhibitors with potent pyroptosis induction properties

Source
Journal of medicinal chemistry - ISSN 0022-2623-68:21 (2025) p. 23163-23184
Author(s)

Structure-property investigation of new "KetoFAPI" inhibitors of fibroblast activation protein (FAP) : discovery of highly potent, selective compounds with prolonged residence times and promising radiotheranostic potential

Source
Journal of medicinal chemistry - ISSN 0022-2623-68:20 (2025) p. 21739-21765