Tess De Bruyne guest lecturer - senior researcher - project coordinator

Research Tess De Bruyne

Research team

Support maintenance scientific equipment. 01/01/2005 - 31/12/2005

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    • Research Project

    Structure-activity relationship investigation in correlation with bioavailability of proanthocyanidins as nutritional antioxidants. 01/01/2003 - 31/12/2006

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      • Research Project

      01/05/2002 - 30/04/2004

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        • Research Project

        High pressure liquid chromatographic techniques with fluorimetric detection for the evaluation of antioxidative parameters in vivo and structure-activity assessment of antioxidative natural products. 01/01/2001 - 31/12/2003

        Abstract

        This project covers the assessment of the in vivo antioxidative properties of natural products. In a first step, rats are stressed with CCl4, after which the concentration of free malondialdehyde and related hydroxyalkenals, determined by means of HPLC, of stressed laboratory animals is compared to the normal, basal concentration. The use of fluorimetric detection enhances both sensitivity and selectivity of the method substantially, important parameters when using small laboratory animals with low MDA plasma concentrations. Subsequently, the in vivo antioxidative effect of some selected polyphenols will be determined, with emphasis on flavonoids and proanthocyanidins. For those compounds structure-activity relationships for in vivo inhibition of lipid peroxidation will be investigated.

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          • Research Project

          Structure elucidation of biologically active natural products as prototypes for new drugs. 01/10/1999 - 30/09/2003

          Abstract

          Biologically active natural products from higher plants are isolated and identified, to serve as prototypes for potential new drugs.

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            • Research Project

            Structure elucidation of biologically active natural products as prototypes for new drugs. 01/10/1996 - 30/09/1999

            Abstract

            Biologically active natural products from higher plants are isolated and identified, to serve as prototypes for potential new drugs.

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              • Research Project

              Chromatographic and structural investigations of ì chemotherapeutically active plant phenolicsì 30/09/1991 - 29/09/1993

              Abstract

              The structure of chemotherapeutically active plant condensed tannins viz. dimeric and trimeric procyanidines of the A, B and C-series will be determined by means of two dimensional nuclear magnetic resonance (2-D-NMR) spectrometry

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                • Research Project

                Chromatographic and structural investigations of ì chemotherapeutically active plant phenolicsì 30/09/1989 - 29/09/1991

                Abstract

                The structure of chemotherapeutically active plant condensed tannins viz. dimeric and trimeric procyanidines of the A, B and C-series will be determined by means of two dimensional nuclear magnetic resonance (2-D-NMR) spectrometry

                Researcher(s)

                Research team(s)

                  Project type(s)

                  • Research Project