2026
Oliviero Cini, Alan Miranda, Daan Willocx, Angeliki Karakasidi, Anke de Groot, Thales do Valle Moreira, Ana P. Leandro, Maria M. M. Santos, Rui Moreira & Filipe Elvas. Development and preclinical evaluation of selective vinyl sulfone-based probes for PET imaging of tumor-associated cathepsins. EJNMMI Radiopharmacy and Chemistry. (2026). DOI: https://doi.org/10.1186/s41181-026-00493-5.Open Access
Hugo Boutier, Anja Feldmann, and Michael Bachmann. The Evolution of FAP-Targeted CAR T-Cell Therapy in Solid Tumors: From Immunotherapy to Immunotheranostic Applications. International Journal of Molecular Sciences. 2026, 27(16), 7425. DOI: https://doi.org/10.3390/ijms27167425. Open Access
Hugo Boutier, Simona Mattiussi, Liliana R. Loureiro, Nicole Berndt, Antonia Stammberger ,Nathalia Jones-Cifuentes, Lydia Hoffmann, Emile Verhulst, Marc Schmitzc, Ingrid De Meester, Umberto M. Battisti, Claudia Arndt, Anja Feldmanna, Frank Roesch, Matthias M. Herth, and Michael Bachmann. Preclinical evaluation of homodimeric FAPI target modules for UniCAR-mediated targeting of FAP-expressing tumor and stromal cells. ONCOIMMUNOLOGY 2026, VOL. 15, NO. 1, 2717836. DOI: https://doi.org/10.1080/2162402X.2026.2717836. Open Access
Simona Mattiussi, Matthias Manfred Herth, Umberto Maria Battisti. Advancing fibroblast activation protein inhibitors for targeted radioligand therapy: Strategies and innovations to increase tumor residence time. European Journal of Medicinal Chemistry. Vol. 309, 5 May 2026, 118737. DOI: https://doi.org/10.1016/j.ejmech.2026.118737. Open Access
2025
Hugo Boutier, Jürgen Kogler, Liliana R. Loureiro, Christin Neuber, Nicole Berndt, Claudia Arndt, Sven Stadlbauer, Holger Stephan, Anja Feldmann, Klaus Kopka, Christoph E. Hagemeyer and Michael Bachmann. Novel immunotheranostic FAP-inhibitor target modules for imaging and elimination of FAP-positive cells by UniCAR T-cells. ONCOIMMUNOLOGY. 2025, VOL. 14, NO. 1, 2598908. DOI: https://doi.org/10.1080/2162402X.2025.2598908. Open Access
Adrianna Bilinska, Naveen Kumar, Silvano Gnesin, Tilman Läppchen, Elena Menéndez, Marcel Martin, Frank Rösch, Axel Rominger & Eleni Gourni. Preclinical evaluation of DOTAGA.Glu.(FAPI)2 and DO3A.Glu.(FAPI)2 as theranostics with human dosimetry extrapolation to lutetium-177 and terbium-161 analogs. European Journal of Nuclear Medicine and Molecular Imaging (2025). DOI: https://doi.org/10.1007/s00259-025-07565-9. Open Access
Alsadig Ahmed Mohammed, Ahmed; Peng, Xuan; Boutier, Hugo; Rodrigues Loureiro, Liliana Raquel; Feldmann, Anja; Hübner, René; Cabrera, Humberto; Kubeil, Manja; Bachmann, Michael; Baraban, Larysa. Exploring Morphology of Thermoplasmonic Nanoparticles to Synergize Immunotherapeutic FAP-positive Cells Sensitization and Photothermal Therapy. Small Science. 2025, 2500099. DOI: https://doi.org/10.1002/smsc.202500099. Open Access
Adrianna Bilinska, Sanjana Ballal, Chandrasekhar Bal, Tilman Läppchen, Eirinaios Pilatis, Elena Menéndez, Euy Sung Moon, Marcel Martin, Frank Rösch, Axel Rominger & Eleni Gourni. Improved FAPI-radiopharmaceutical pharmacokinetics from the perspectives of a dose escalation study. European Journal of Nuclear Medicine and Molecular Imaging (2025). DOI: https://doi.org/10.1007/s00259-025-07141-1. Open Access
2024
Julie van Krimpen Mortensen, Simona Mattiussi, Lars Hvass, Emilie Graae Lund, Vladimir Shalgunov, Frank Roesch, Umberto Maria Battisti, Matthias Manfred Herth, and Andreas Kjaer. [68Ga]Ga-DOTAGA-Glu(FAPi)2 Shows Enhanced Tumor Uptake and Theranostic Potential in Preclinical PET Imaging. Diagnostics 2024; 14(18):2024. DOI: doi.org/10.3390/diagnostics14182024. Open Access
Tilman Läppche, Adrianna Bilinska, Eirinaios Pilatis, Elena Menéndez, Surachet Imlimthan, Euy Sung Moon , Ali Afshar-Oromieh, Frank Rösch, Axel Rominger and Eleni Gourni. Tailoring Fibroblast-Activation Protein Targeting for Theranostics: A Comparative Preclinical Evaluation of the 68Ga- and 177Lu-Labeled Monomeric and Dimeric Fibroblast-Activation Protein Inhibitors DOTA.SA.FAPi and DOTAGA.(SA.FAPi)2. Molecules. 2024; 29(13):3093. DOI: doi.org/10.3390/molecules29133093. Open Access
Hugo Boutier, Liliana R. Loureiro, Lydia Hoffmann, Claudia Arndt, Tabea Bartsch, Anja Feldmann and Michael P. Bachmann. UniCAR T-Cell Potency—A Matter of Affinity between Adaptor Molecules and Adaptor CAR T-Cells? International Journal of Molecular Sciences. 2024; 25(13):7242. DOI: doi.org/10.3390/ijms25137242. Open Access