OncoProTools wants to force breakthroughs in cancer diagnosis and therapy, relying on innovative protease targeting technologies. The consortium’s Research Mission is represented by the following three main research objectives: 

Research Objective 1 | WP1: Safer and more effective CAR T therapy:

Explore innovative venues for protease targeting: towards safer and more effective CAR T cell therapies for cancer patients.

Research Objective 2 | WP2: Novel Ligands for other TME proteases:

Discover novel vectors for tumor targeting that bind to other TME proteases: cathepsins S, B, L and granzyme B.

Research Objective 3 | WP3: Personalized protease targeting: 

Personalize applications of protease targeting through deeper understanding of TME biology and minimally invasive, miniaturized diagnostics.