Semisynthetic triterpenes led to the generation of selective antitrypanosomal lead compounds
Chemical biology and drug design - ISSN 1747-0277-99:6 (2022) p. 868-883
Fernanda Guilhon-Simplicio, Carlos Klinger Rodrigues Serrao, Ana Cristina da Silva Pinto, Paulo Anastacio Furtado Pacheco, Robson Xavier Faria, David Rodrigues Rocha, Vitor Francisco Ferreira, Raimundo Carlos Pereira-Junior, An Matheeussen, Adrienn Baán, Filip Kiekens, Maria Meneses de Pereira, Emerson Silva Lima, Hans De Winter, Paul Cos
LEADD : Lamarckian evolutionary algorithm for de novo drug design
Journal of Cheminformatics - ISSN 1758-2946-14:1 (2022) p.
Genomic and phenotypic characterization of experimentally selected resistant **Leishmania donovani** reveals a role for dynamin-1-like protein in the mechanism of resistance to a novel antileishmanial compound