Highlights in gastro-intestinal cancer

Source
Belgian journal of medical oncology - ISSN 1784-7141-12 (2018) p. 182-188
Author(s)

Afatinib for advanced cancers carrying an EGFR, HER2, or HER3 mutation : an open-label, phase II, Belgian precision study

Source
JCO Precision Oncology - ISSN 2473-4284-10:7 (2026) p.
Author(s)
    Lore Decoster, Philippe Aftimos, Sylvie Rottey, Hans Prenen, Joelle Collignon, Jeroen Mebis, Jean Luc Canon, Vanessa Fastenaekels, Nadia Cappoen, Anna Kondrat, Sofie Joris, Jacques De Greve

Amivantamab monotherapy in chemorefractory RAS/BRAF wild-type metastatic colorectal cancer : results from OrigAMI-1, an open-label, phase Ib/II study

Source
Journal of clinical oncology - ISSN 0732-183X-44:17 (2026) p. 1624-1634
Author(s)
    Paul E. Oberstein, J. Randolph Hecht, Kanwal Raghav, Filippo Pietrantonio, Dirk Arnold, Victor Moreno, Eric Van Cutsem, Rozita Abdul Malik, Yong Sang Hong, Myung Ah Lee, Harvey Yu-Li Su, Jeeyun Lee, Sreenivasa Chandana, Marcia Cruz-Correa, Ying Yuan, Azura Ahmad, Kuan-Ming Lai, Hung-Chih Hsu, Eric Xueyu Chen, Elena Elez, Chia-Chi Lin, Carlos Lopez, Hans Prenen, Susana Rosello-Keranen, Hector Velez, Yu-Min Yeh, Volker Heinemann, Cathy Eng, Seung-Hoon Beom, Sabine Tejpar, Sanjib Chowdhury, Xuesong Lyu, Medha Kamat, Joshua C. Curtin, Bharvin Patel, John Xie, Rianka Bhattacharya, Robert W. Schnepp, Emrullah Yilmaz, Ryota Iwasawa, Mahesh Daksh, Patricia Lorenzini, Meena Thayu, Mahadi Baig, Han Sang Kim, Sae-Won Han

Phase I study of mosperafenib, a novel paradox breaker B-Raf proto-oncogene serine/threonine kinase (BRAF) inhibitor, in patients with BRAF V600-mutant solid tumors

Source
Journal of clinical oncology - ISSN 0732-183X-44:14 (2026) p. 1337-1348
Author(s)
    Maria Vieito, Elisa Fontana, Catherine H. Han, Eduardo Castanon, David J. Pinato, Oliver Bechter, Rikke L. Eefsen, Irene Moreno, Hans Prenen, Reinhard Dummer, Ruth Plummer, Gabriel Schnetzler, Martin Kornacker, Piergiorgio Pettazzoni, Florian Renner, Mahdi About, Martha L. Serrano-Serrano, Christina Godfried Sie, Abiraj Keelara, Andreas Roller, David Dejardin, Elisa Cinato, Tomi Fakolade, Ernesto Guarin, Nick Flinn, Nicole A. Kratochwil, Nino Keshelava

Protein-level profiling of TIGIT axis components in human PDAC reveals immune-suppressive expression patterns

Source
Cancer immunology and immunotherapy - ISSN 0340-7004-75:4 (2026) p. 1-17