Louis Maes emeritus with assignment

Publications Louis Maes

Lead optimization of the 5-phenylpyrazolopyrimidinone NPD-2975 toward compounds with improved antitrypanosomal efficacy

Source
Journal of medicinal chemistry - ISSN 0022-2623-67:4 (2024) p. 2849-2863
Author(s)
    Yang Zheng, Magali Van den Kerkhof, Mohamed Ibrahim, Iwan J.P. De Esch, Louis Maes, Geert Jan Sterk, Guy Caljon, Rob Leurs

DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc₁

Source
Science translational medicine - ISSN 1946-6234-15:726 (2023) p.
Author(s)
    Stéphanie Braillard, Martine Keenan, Karen J. Breese, Jacob Heppell, Michael Abbott, Rafiqul Islam, David M. Shackleford, Kasiram Katneni, Elly Crighton, Gong Chen, Rahul Patil, Given Lee, Karen L. White, Sandra Carvalho, Richard J. Wall, Giulia Chemi, Fabio Zuccotto, Silvia González, Maria Marco, Julianna Deakyne, David Standing, Gino Brunori, Jonathan J. Lyon, Pablo Castañeda-Casado, Isabel Camino, Maria S. Martinez Martinez, Bilal Zulfiqar, Vicky M. Avery, Pim-Bart Feijens, Natascha Van Pelt, An Matheeussen, Sarah Hendrickx, Louis Maes, Guy Caljon, Vanessa Yardley, Susan Wyllie, Susan A. Charman, Eric Chatelain

Discovery of 5-phenylpyrazolopyrimidinone analogs as potent antitrypanosomal agents with in vivo efficacy

Source
Journal of medicinal chemistry - ISSN 0022-2623-66:15 (2023) p. 10252-10264
Author(s)
    Yang Zheng, Magali Van den Kerkhof, Tiffany van der Meer, Sheraz Gul, Maria Kuzikov, Bernhard Ellinger, Iwan J.P. de Esch, Marco Siderius, An Matheeussen, Louis Maes, Geert Jan Sterk, Guy Caljon, Rob Leurs

Structural optimization of BIPPO analogs as potent antimalarials

Source
Molecules: a journal of synthetic chemistry and natural product chemistry - ISSN 1420-3049-28:13 (2023) p. 1-16
Author(s)

To target or not to target Schistosoma mansoni cyclic nucleotide phosphodiesterase 4A?

Source
International journal of molecular sciences - ISSN 1422-0067-24:7 (2023) p. 1-18
Author(s)
    Yang Zheng, Susanne Schroeder, Georgi K. Kanev, Sanaa S. Botros, Samia William, Abdel-Nasser A. Sabra, Louis Maes, Guy Caljon, Carmen Gil, Ana Martinez, Irene Garcìa Salado, Koen Augustyns, Ewald Edink, Maarten Sijm, Erik de Heuvel, Iwan J.P. de Esch, Tiffany van der Meer, Marco Siderius, Geert Jan Sterk, David Brown, Rob Leurs