Research Paul Van Royen

Abstract

This project concerns a literature study in the context of the development of transmural integrated care pathways in the regional care zone Antwerp for elderly patients with chronic care problems. This is a scoping review of transmural care pathways (what types of transmural care pathways exist internationally, in which contexts, i.e. which interventions in which circumstances, but also into which effects were intended and possibly achieved). At the same time, a search will be launched to make an inventory of already started transmural care pathways for this target group throughout Belgium.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project includes the administrative support of the Working Group Development of Primary Care Guidelines, financed by RIZIV. The task indulged the development, adaptation and update of Belgian Guidelines. The assignment within this project includes financial support of the project -

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The Alivia pilot project aims to test a digital tool, developed by the Flemish government, to promote targeted and integrated care for citizens, informal caregivers and care providers (medical, non-medical and welfare). The Antwerp region is one of the two pilot regions where testing will take place in two care settings: palliative setting and chronic care and support needs in the home situation.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

European society is becoming increasingly diverse due to high levels of migration. Persons with a migration background, especially those from non-western countries, may experience significant challenges when they seek medical care. Some of the main issues arise in the context of medical decision-making, where cultural preferences for close family involvement may be difficult to reconcile with the western model of medicine, as enshrined in health law and medical deontology. This is the first comprehensive research project on medical decision-making in patients with a migration background undertaken in the European context. It brings together state-of-the-art expertise in health sciences, medical sociology, and health law, and applies a transversal research design and a tailored socio-legal research methodology. In this way, we will gain crucial insight into the relevant preferences of patients with a migration background and into strategies and tools that may be legally acceptable to improve medical decision-making in a diversity-responsive way. More specifically, the goals of the proposed research are threefold, each corresponding to a major research gap and therefore groundbreaking. The first research goal is to examine the preferences and challenges of patient populations with a migration background regarding medical decision-making, with particular attention to the role of family members in this process, and the variations that may exist between and within these groups. The second research goal is to investigate the practical strategies and tools that general practitioners have developed to address these preferences and challenges. The third research goal is to analyze how much room Belgian health law currently leaves for responding to these preferences and whether this legal framework should be reinterpreted or amended in the light of the "human right to culturally appropriate healthcare". The overarching aim is to improve diversity-responsive, patient-oriented care for the migrant population, by identifying those strategies and tools that may be legally acceptable to accommodate patient preferences and by incorporating them in policy and legal recommendations, as well as in an educational module for physicians and information materials for patients, families, and healthcare workers. The project uses a mixed-methods design, combining desk research and quantitative (factorial survey with hypothetical vignettes) and qualitative (focus group discussions, in-depth interviews and nominal group method) research methodologies. The research team will jointly review the results from the three perspectives, by using multiperspective qualitative methods. With its aim to examine and improve diversity-responsive, patient-oriented care for the migrant population, our research project aligns closely with the vision statement of the University of Antwerp on fostering diversity and equal opportunities, as well as with current national and international political and research priorities. Supporting an inclusive society by reducing inequalities and social exclusion is a priority action point for the European Commission, the Council of Europe, the UN, and the WHO. International policy instruments highlight that inequalities in access to healthcare are growing and particularly affect vulnerable groups, including patients with a migration background. Consequently, they call for measures to guarantee that every person effectively obtains a satisfactory degree of care. In contributing to this goal, our research project addresses central policy and research priorities. The project is therefore expected to result in major opportunities to obtain European and other international funding, and to form the basis for international research collaborations, taking into account similar challenges arising in other European countries. In this way, the project will also significantly increase the international visibility of the University of Antwerp.

Researcher(s)

• Promoter: Van Assche Kristof
• Co-promoter: Van de Velde Sarah
• Co-promoter: van Olmen Josefien
• Co-promoter: Van Royen Paul
• Co-promoter: Vansweevelt Thierry

Research team(s)

• Personal Rights and Property Rights

Project type(s)

• Research Project

Abstract

This includes the coordination and the chair of the Working Group Development of Primary Care Guidelines, financed by RIZIV. The task indulged the development, adaptation and update of Belgian Guidelines. The assignment within this project includes the following tasks: - Content coordination for the working group development primary care guidelines (preparing, organizing and chairing the meetings of the working group and steering group, contacts with author groups, stakeholders and experts, with RIZIV and EBPracticeNet, website management workgroup). - The development of a team of expertise for the working group. For the systematic approach and methodologically correct development of guidelines revisions, a central expertise section is being developed consisting of some part-time academic staff members. The following tasks will be included for each guideline: elaboration of a systematic literature search, quality assessment and extraction of data, implementation of the various steps of the ADAPTE procedure, finalization and publication of the guideline, final editing, translation to other languages and final editing, preparation of publication. In addition, the Expertise group will also work on the regular updating of the Guidance Development Manual, as well as the development of templates and tools for guideline development - guidance of development of guidelines by external partners and of Federal FOD projects concerning development of guidelines

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

In 2018, 6% of people over the age of 15 had a depressive disorder in the Flemish Region (Statistiek Vlaanderen). In 2019, this was 36 million people per year for Europe, good for 92 billion euros in annual costs (WHO Global Burden of Disease 2019). The WHO estimates that depression will be one of the leading causes of disease burden by 2030. Depression, however, is very heterogeneous, with an estimate of 33-40% responding poorly or not at all to gold standard treatment. Innovation in the field of treatment could therefore have a major impact for this subgroup. This project aims to repurpose two established anti-inflammatory compounds as adjuvant therapy for immune-mediated depression, in line with state-of-the-art research of the last 10 years. Immune-mediated depression represents a subtype which accounts for approximately 30% of depressive disorders (Osimo et al., 2019). Patients with this immunosubtype are more likely to have a higher severity of depression, a lower quality of life and more somatic symptoms (Foley et al., 2021). Furthermore, it is accompanied by a high incidence of treatment resistance (Carvalho et al., 2013). While their mechanisms of action completely differ from those of existing antidepressant treatment options, immunomodulatory drugs celecoxib and minocycline have proven their merit as add-on treatment in depressive episodes. They have been on the Belgian market for years and come with a known pharmacological and safety profile. Patient stratification at baseline based on inflammatory status will reveal which inflammatory subpopulation benefits most from each of the two investigated anti-inflammatory compounds. Additionally, our distinctive study design allows head-to-head comparison of both add-on therapies and will as such provide the last stepping stones towards clinical implementation of individualised treatment strategies in depression. The novelty and clinical relevance of this project reside in (1) the direct comparison of each compound separately as well as (2) the selection of patients who may benefit from anti-inflammatory treatment via stratification based on baseline inflammatory levels. Hence, this project will tackle a knowledge gap vital for the development of clinical practice guidelines. The addition of this treatment option to the psychiatric arsenal and the inflammation-based stratification prior, opens the way to a pragmatic strategy in the form of personalised medicine in biological psychiatry. This could support and optimise the choice of psychiatric treatment, thus limiting exposure to ineffective treatments and shortening the length of hospital stay. As a result, this repurposing strategy will significantly reduce the associated health care costs, without the additional costs associated with bringing new compounds to market. Objectives Validate the efficacy of immune-targeted augmentation with minocycline or celecoxib in a Flemish cohort of patients with MDD who failed to remit with one or two trials of antidepressant treatment; Compare the respective acceptability, treatment response and remission rates of minocycline and celecoxib as adjunctive therapy; Compare the efficacy of both compounds as adjunctive therapy in an immune-mediated subtype of MDD versus an unstratified patient sample; Evaluate the use of hsCRP as a predictor for treatment response to minocycline and celecoxib.

Researcher(s)

• Promoter: Morrens Manuel
• Co-promoter: De Picker Livia
• Co-promoter: Van Royen Paul

Research team(s)

• Collaborative Antwerp Psychiatric Research Institute (CAPRI)

Project website

Project type(s)

• Research Project

Abstract

Within the framework of the Chair of the Province of Antwerp – Healthcare professions in evolution - PAZOE, financed by the partnership between the Province of Antwerp, Governor Kinsbergen Center (GKC) and University of Antwerp, we are investigating the important dropout and outflow within healthcare professions. More specifically, how the care and welfare sector can deal with the capacity shortages of careproviders in combination with the growing and changing demand for care from society. The healthcare sector is undergoing many changes and is also facing major challenges in the province of Antwerp. The transition from (health)care education to the labor market is difficult. As a result, there are staff shortages. On the other hand, the demand for care from society is increasing due to more chronic, complex care and the increasing aging of the population. Using mixed-method research methods, as well as implementation research, we will (1) analyze and synthesize existing initiatives on working and learning differently within the healthcare sector; (2) build a learning network; (3) roll out three pilot projects based on the initial analysis, supported by the learning network, initially in the primary care zones Middenkempen and De Rupelaar. The chair also wants to ensure a connection between various ongoing projects in interprofessional collaboration between professionals and organizations in the healthcare sector.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Van Bogaert Peter

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project website

Project type(s)

• Research Project

Abstract

This project concerns the development of a partial update of the Domus Medica guideline chronic heart failure. Six clinical questions will be answered : 1. Which self-management/selfcare support is recommended for patients with chronic heart failure ? 2. Which pharmacological treatment is (not) recommended for patients with chronic heart failure? 3. Which follow-up is recommended for patients with chronic heart failure ( specifically after starting-up medication, for anemia)? 4. Which multidisciplinary care is recommended for patients with chronic heart failure? 5. Which type of cardiac revalidation is recommended for patients with chronic heart failure? 6. When is referral to a cardiologist recommended for patients with chronic heart failure? The guideline development follows the ADAPTE procedure and it includes an extensive literature search. Literature will be critically assessed and in formulating recommendations the GRADE and Evidence-to decision frameworks are used

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This includes the coordination and the chair of the Working group Development of Primary Care Guidelines, financed by RIZIV. The task indulged the development and adaptation of Belgian Guidelines. This task is part of the Federal EBP Plan 2021-2025. The assignment within this project includes the following tasks: - Content coordination for the working group development primary care guidelines (preparing, organizing and chairing the meetings of the working group and steering group, contacts with author groups, stakeholders and experts, with RIZIV and EBPracticeNet, website management workgroup). - The development of a team of expertise for the working group. For the systematic approach and methodologically correct development of guidelines revisions, a central expertise section is being developed consisting of some part-time academic staff members. The following tasks will be included for each guideline: elaboration of a systematic literature search, quality assessment and extraction of data, implementation of the various steps of the ADAPTE procedure, finalization and publication of the guideline, final editing, translation to other languages and final editing, preparation of publication. In addition, the Expertise group will also work on the regular updating of the Guidance Development Manual, as well as the development of templates and tools for guideline development - guidance of development of guidelines by external partners and of Federal FOD projects concerning development of guidelines

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The aim is to develop a multidisciplinary good clinical practice guideline on oncological post-acute care in primary care, according to the international standards for the development of an evidence-based guideline and the criteria used by the Belgian Centre for Evidence-Based Medicine (CEBAM) for the validation of guidelines.

Researcher(s)

• Promoter: van Olmen Josefien
• Co-promoter: De Groef An
• Co-promoter: Van Royen Paul
• Co-promoter: Wens Johan

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Given the crucial role of health promotion and disease prevention in primary care and the limited attention paid to it in current training programmes in Belgium, there is a need for capacity building for disease prevention and health promotion for primary care professionals. With this project, we formulate strategies for a better embedding of health promotion and disease prevention in primary care training, based on international standards and using a European network. The project is carried out by a multidisciplinary consortium of two academic partners from both language areas -University of Antwerp (UA) and Université Catolique de Louvain (UCL) - and the expertise centre on health promotion - Vlaams Instituut Gezond Leven (GL). The multidisciplinary research team consists of general practitioners, psychologists, educational experts and communication scientists. The research group can call upon an extensive steering committee of stakeholders with representatives of care users, educational institutes, professional organisations and policy makers from both parts of the country, both during the inventory phase and for the development of the strategy and dissemination. The inclusion of representatives of vulnerable target groups in the steering committee guarantees specific attention to the needs and input of these groups. The development of strategies is done in 3 phases, organised in 3 work packages. In WP1 we will elaborate a Belgian frame of reference for the provision and quality of education in health promotion and disease prevention through desk research. Existing international frameworks such as the core skills set for health promotion workers by the International Union for Health Promotion and Education (IUHPE) are the starting point for a cross-professional frame of reference adapted to the Belgian context. In WP2, we will make an inventory of the existing provision and of the quality of health promotion and disease prevention in primary health care training in Belgium through a survey starting from the stakeholder network. This also includes a comparative analysis with training courses in other European countries, through the research group's connections to European networks. The trainings will be analysed based on the frame of reference developed in WP1 and Clement's didactic model. WP3 will focus on the development of strategies for the envisaged embedding of health promotion and disease prevention in primary care training based on the results of WP1 and WP2. By means of co-creation work sessions, the research group together with stakeholders will develop a draft strategy in the form of an educational package, which will be tested in a Delphi procedure. The dissemination to training institutes, professional and scientific organisations, target groups and policy makers and the creation of a support base for concrete strategies will take place together with the steering committee. A final symposium and publications in professional journals will contribute to this.

Researcher(s)

• Promoter: van Olmen Josefien
• Co-promoter: Bastiaens Hilde
• Co-promoter: Michels Nele
• Co-promoter: Van Royen Kathleen
• Co-promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project aims to perform a first mapping of the instruments, frameworks, and perspectives that are relevant in preventing, detecting, and addressing elder abuse in Belgium. The results of this research will provide the foundations for future research aimed at establishing and implementing an interprofessional protocol that is able to adequately respond to elder abuse.

Researcher(s)

• Promoter: Van Assche Kristof
• Co-promoter: Barbaix Renate
• Co-promoter: Bastiaens Hilde
• Co-promoter: Peremans Lieve
• Co-promoter: Swennen Frederik
• Co-promoter: Van Royen Paul

Research team(s)

• Personal Rights and Property Rights

Project type(s)

• Research Project

Abstract

The Health Insurance Board of the RIZIV has asked the EBPracticeNet vzw Working Group Development Primary Care Guidelines to include the development and adaptation of Belgian Guidelines. This work is part of the Federal EBP Plan 2021-2025 The assignment within this project includes the following tasks: - Content coordination for the working group development primary care guidelines (preparing, organizing and chairing the meetings of the working group and steering group, contacts with author groups, stakeholders and experts, with RIZIV and EBPracticeNet, website management workgroup). - The development of a team of expertise for the working group. For the systematic approach and methodologically correct development of guidelines revisions, a central expertise section is being developed consisting of some part-time academic staff members. The following tasks will be included for each guideline: elaboration of a systematic literature search, quality assessment and extraction of data, implementation of the various steps of the ADAPTE procedure, finalization and publication of the guideline, final editing, translation to other languages and final editing, preparation of publication. In addition, the Expertise group will also work on the regular updating of the Guidance Development Manual, as well as the development of templates and tools for guideline development - guidance of development of guidelines by external partners and of Federal FOD projects concerning development of guidelines

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Today we notice that initiatives are being taken on interprofessional collaboration in practice but there is a lack of experience and knowledge sharing, adapted training module for practice, working model with involvement of management, ... IPCIHC-4U wants to use a validated scan of interprofessionality, supplemented with possible tailor-made training modules, offering healthcare organizations (focus on residential care centers with more than 100 residents) a quality improvement project

Researcher(s)

• Promoter: Tsakitzidis Giannoula
• Co-promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The aim of this project to gather routine data through automatic data collection in a safe environment and to giva accurate and rapidly available information to health care providers and researchers.This project is part of a research between the university of Antwerp and the Flemish government.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The Health Insurance Board of the RIZIV has asked the EBPracticeNet vzw Working Group Development Primary Care Guidelines to include the development and adaptation of Belgian Guidelines. With a part-time staff member of Wit Gele Kruis, a team of expertise is developed for the working group, for the systematic approach and methodologically correct development of guidelines revisions. The following tasks will be included for each guideline: elaboration of a systematic literature search, quality assessment and extraction of data, implementation of the various steps of the ADAPTE procedure, finalization and publication of the guideline, final editing, translation to other languages and final editing, preparation of publication. In addition, the Expertise group will also work on the regular updating of the Guidance Development Manual, as well as the development of templates and tools for guideline development

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The Health Insurance Board of the RIZIV has asked the EBPracticeNet vzw Working Group Development Primary Care Guidelines to include the development and adaptation of Belgian Guidelines. There will be a constant activity for the development of 2 multidisciplinary Belgian guidelines and the revision / updating of 5 Belgian guidelines for primary care per year. The assignment within this project includes the following tasks: - Content coordination for the working group development primary care guidelines (preparing, organizing and chairing the meetings of the working group and steering group, contacts with author groups, stakeholders and experts, with RIZIV and EBPracticeNet, website management workgroup). - The development of a team of expertise for the working group. For the systematic approach and methodologically correct development of guidelines revisions, a central expertise section is being developed consisting of some part-time academic staff members. The following tasks will be included for each guideline: elaboration of a systematic literature search, quality assessment and extraction of data, implementation of the various steps of the ADAPTE procedure, finalization and publication of the guideline, final editing, translation to other languages and final editing, preparation of publication. In addition, the Expertise group will also work on the regular updating of the Guidance Development Manual, as well as the development of templates and tools for guideline development

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

In Uganda, 98.9% of rural children developed infections caused by microorganisms resistant to the antibiotic co-trimoxazole (Rutebemberwa 2015). Antibiotic-resistant bacteria increasingly challenges treatment of pneumonia and tuberculosis. Despite this, Uganda has no national policy to deal with antibiotic resistance, and very little public understanding of the consequences of inappropriate use of medicines. This project will contribute to the reduction of antimicrobial resistance in Uganda by increasing the research activity and capacity of the Faculty of Health Science at Busitema University, and providing evidenced-based solutions to reduce antimicrobial resistance. The project maps patterns of antibiotic resistance in Uganda, and the factors which drive them in four regions. Capacity building includes training Ugandan researchers in advanced quantitative and qualitative research methods, and publishing in ISI ranked journals. Dissemination includes training, workshops and training material for health professionals, and raising public awareness

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The Health Insurance Board of the RIZIV has asked the EBMPracticeNet vzw Working Group Development Primary Care Guidelines to include the development and adaptation of Belgian Guidelines. There will be a constant activity for the development of 2 multidisciplinary Belgian guidelines and the revision / updating of 10 Belgian guidelines for primary care per year. The assignment within this project includes the further development of a team of expertise for the working group. For the systematic approach and methodologically correct development of guidelines revisions, a central expertise section is being developed consisting of some part-time academic staff members. The following tasks will be included for each guideline: elaboration of a systematic literature search, quality assessment and extraction of data, implementation of the various steps of the ADAPTE procedure, finalization and publication of the guideline, final editing, translation to other languages and final editing, preparation of publication. In addition, the Expertise group will also work on the regular updating of the Guidance Development Manual, as well as the development of templates and tools for guideline development

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project website

Project type(s)

• Research Project

Abstract

The Health Insurance Board of the RIZIV has asked the EBMPracticeNet vzw Working Group Development Primary Care Guidelines to include the development and adaptation of Belgian Guidelines. There will be a constant activity for the development of 2 multidisciplinary Belgian guidelines and the revision / updating of 10 Belgian guidelines for primary care per year. The assignment within this project includes the following tasks: - Content coordination for the working group development primary care guidelines (preparing, organizing and chairing the meetings of the working group and steering group, contacts with author groups, stakeholders and experts, with RIZIV and EBMPracticeNet, website management workgroup). - The development of a team of expertise for the working group. For the systematic approach and methodologically correct development of guidelines revisions, a central expertise section is being developed consisting of some part-time academic staff members. The following tasks will be included for each guideline: elaboration of a systematic literature search, quality assessment and extraction of data, implementation of the various steps of the ADAPTE procedure, finalization and publication of the guideline, final editing, translation to other languages and final editing, preparation of publication. In addition, the Expertise group will also work on the regular updating of the Guidance Development Manual, as well as the development of templates and tools for guideline development

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project website

Project type(s)

• Research Project

Abstract

The overall research objective of the SPICES project is to implement and evaluate a comprehensive CVD prevention and control program in five settings: a rural & semi-urban community in a low-income country (Uganda), middle income (South Africa) and vulnerable groups in three high-income countries (Belgium, France and United Kingdom) as well as to identify and compare the barriers and facilitators across study contexts. The project will be evaluated using a mix of qualitative and quantitative methods. At the beginning of the project, we will conduct baseline assessments including literature reviews, formative studies, household surveys (where feasible) and learn lessons from other projects to understand healthcare and lifestyle practices, barriers, and facilitators. A costeffectiveness and cost benefit analysis will be included. In addition, the teams will conduct site exchanges visits to learn from each other and organise policy dialogues to ensure sustainability and maximise impact of the interventions.

Researcher(s)

• Promoter: Bastiaens Hilde
• Co-promoter: Anthierens Sibyl
• Co-promoter: Van geertruyden Jean-Pierre
• Co-promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project website

Project type(s)

• Research Project

Abstract

Distress and quality of life during the diagnostic phase and before starting treatment in patients with lung cancer. This study aimed to get insight into the contributing factors to the diagnostic work-up time of lung cancer in the outpatient setting in specialist care, especially in the psychosocial burden for lung cancer patients during the diagnostic work-up . The aim is also to get insight in the way the diagnostic work-up is organised and how the usual care in Flanders is. The findings will provide insights into care trajectories which are relevant for the customization of care according to the patient's needs. There are two parts in the study: - a descriptive prospective study in patients with a (suspected serious) lung disease during the diagnosis process. A quantitative study with the use of standardised questionnaires - Qualitative semi-structured interviews were conducted with ten pulmonologists in Flanders to explore how the diagnosis of lung cancer is being made in the outpatient setting.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project website

Project type(s)

• Research Project

Abstract

The knowledge database of EBMPracticeNet includes all National Belgian EBM-information products, including the adapted Duodecim guidelines and all Belgian updated monodisciplinary and multidisciplinary guidelines. Within this project the researcher has the ultimate responsibility for the development of the online knowledge base. He/she is responsible for the actualization, coherence and integration of all guidelines and the other Belgian EBM products. There is a strong collaboration with the working group for the development of primary care guidelines, the project leader and the responsible for the clinical decision support system

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Coenen Samuel
• Co-promoter: Remmen Roy

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project website

Project type(s)

• Research Project

Abstract

In the past 5 years, Prof Jean-Pierre Van geertruyden has developed a portfolio of multiple global health research project and programmes, such as large surveys, diagnostic studies and clinical trials in the Democratic Republic of Congo, Peru, Tanzania, Uganda, Zambia and South Africa. More specifically, he is principal or co-investigator of ongoing or recently complete research studies with a focus on parasitological diseases financed by VLIR-UOS, Imperial College, FWO and EDCTP. The present project will focus on parasitological diseases research. Host, parasite and environmental related predictors associated with recurrent P. falciparum infections will be studied, using the clinical and sample databases developed through these studies. Key knowledge on targets and mechanisms of protective immunity is surprisingly limited, with many studies giving negative or contradictory results. The present project builds on two 3-years prospective longitudinal trials. Host, environmental and parasite related factors associated with individual susceptibility to malaria will be assessed. In collaboration with international partners and within a multidisciplinary setting, correlations between the development of clinical immunity and relevant clinical epidemiological features will be explored. This will enable a better understanding of the P. falciparum parasite's biology and host immunology and open new opportunities for malaria control.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project represents a research contract awarded by the University of Antwerp. The supervisor provides the Antwerp University research mentioned in the title of the project under the conditions stipulated by the university.

Researcher(s)

• Promoter: Mortelmans Dimitri
• Co-promoter: Swennen Frederik
• Co-promoter: Van Royen Paul

Research team(s)

• Centre for Population, Family and Health

Project type(s)

• Research Project

Abstract

Proposed by the University, the Francqui Foundation each year awards two Francqui Chairs at the UAntwerp. These are intended to enable the invitation of a professor from another Belgian University or from abroad for a series of ten lessons. The Francqui Foundation pays the fee for these ten lessons directly to the holder of a Francqui Chair.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project represents a formal research agreement between UA and on the other hand the Flemish Public Service. UA provides the Flemish Public Service research results mentioned in the title of the project under the conditions as stipulated in this contract.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Coenen Samuel
• Co-promoter: Remmen Roy

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

National referral systems for THB victims exist, but are mostly missing a health component. The health professionals who encounter the victim lack necessary information about how and where to refer a trafficked person and what are the existing services available in a given country. The health professionals are per definition responsible for the weil being of the person and when facing a trafficked victim should decide quickly on the next step. This project focuses on the development of guidelines, made through a consensus method by international experts on THB, for the establishment of national focal points that include health care experts, working together with law enforcement agencies and NGO's. Involvement of the university in this project is aimed at developing guidelines through a research method (consensus Delphi Survey technique). With the focus set on the health care, more victims will be detected and more information will become available for the purpose of juridical proceedings leading to an increased number of convictions.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Peeraer Griet

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The scope of this project is to support medical curriculum reform at the UTPL with emphasis on modern teaching concepts, and to extend this reform to other universities which is in line with the MoH strategy.

Researcher(s)

• Promoter: Hendrickx Kristin
• Co-promoter: Remmen Roy
• Co-promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The goal of this project would be the creation of a workgroup which would 1) investigate the knowledge and expertise which is already available within the University of Antwerp (faculty of medicine) regarding evidence-based medicine and systematic reviews/meta-analyses/Cochrane reviews; 2) training and support of candidate systematic reviewers in the field of cancer prevention; 3) to collaborate in the Cochrane review group and 4) to develop and promote activities of evidence-based cancer prevention throughout the University which could result, in the future, in the creation of the Cochrane field on cancer prevention.

Researcher(s)

• Promoter: Bogers John-Paul
• Co-promoter: Van Royen Paul

Research team(s)

• Laboratory of cell biology and histology

Project type(s)

• Research Project

Abstract

This project represents a formal research agreement between UA and on the other hand Universiteit Maastricht. UA provides Universiteit Maastricht research results mentioned in the title of the project under the conditions as stipulated in this contract.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The overall aim of this project is the development of best practice guidelines for the detection, prevention and treatment of substances abuse in children and youngsters age 12 tot 25, using the ADAPTE process.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project represents a formal service agreement between UA and on the other hand Domus Medica vzw. UA provides Domus Medica vzw research results mentioned in the title of the project under the conditions as stipulated in this contract.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project represents a formal service agreement between UA and on the other hand Domus Medica vzw. UA provides Domus Medica vzw research results mentioned in the title of the project under the conditions as stipulated in this contract.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project represents a formal research agreement between UA and on the other hand a private institution. UA provides the private institution research results mentioned in the title of the project under the conditions as stipulated in this contract.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

TRANSFoRm will develop rigorous, generic methods for the integration of Primary Care clinical and research activities, to support patient safety and clinical research via: - rich capture of clinical data, including symptoms and signs rather than just a clinical diagnosis. A generic, dynamic interface, with potential to operate with any electronic health record (eHR), will facilitatie both diagnostic decision support and identification of patients eligible for research, thus enhancing patient safety - distributed interoperability of eHR data and other data sources that maintains provenance, confidentiality and security. This will enable large-scale phenoptype-genotype association studies and follow-up of trials. - software tools and services to enable use of controlled vocabulary and standardised data elements in clinical research. This will enable integration and reuse of clinical data. The scientific aims of this project are to radically advance our understanding of ICT system interoperability relevant to healthcare and clinical research and to develop an EU-wide system capable of integrating Primary Care electronic health record systems and research systems.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Vermeire Etienne
• Co-promoter: Wens Johan

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project website

Project type(s)

• Research Project

Abstract

The aim of the project is to improve Primary Health Care and Family Medicine (PHC/FM) in Ecuador. This will be achieved by training family physicians who contribute to primary interdisciplinary health care services, oriented towards the real needs of patients, their family and their community. For this the project has 3 dimensions: research, capacity building and extension. In the first phase, research will include defining indicators for PCH/FM and for medical education in Ecuador. Building, implementing and evaluating a PHC/FM oriented medical curriculum at the local partner university will increase the capacity and the performance of trained doctors on different levels: undergraduate, postgraduate and continuing Medical Education. In the project, 3 PhD will evaluate the effect of the renewal of the curriculum on different aspects, and will be trained and incorporated as teachers and researchers in health care areas, strenghtening the research capacity at the local and national level. Finally, networking will be essnetial to ensure the sustainability of the results of the project. This will include the dissemination of the results of our project towards the different involved stakeholders.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Hendrickx Kristin
• Co-promoter: Remmen Roy

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Editor of the magazine "Huisarts Nu".

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The conduct of an analysis of the literature for a RIZIV consensus conference on 'Influenza: vaccines and antiviral medication.' A consensus conference is a method which is useful for the development of medical and professional guidelines that take up a position concerning a controversy of a medical procedure, with the final goal of enhancing the quality of medical care. This consensus is reached by a jury that bases its decisions on the work of the bibliography working group and experts in the field. The bibliography group's task is to retrieve all relevant literature and to judge its methodological quality in order to be able to answer clinical questions that are drawn by the RIZIV Organising Committee. The answers of the bibliography working group and the jury are being accompanied by levels of scientific evidence and levels of recommendation for clinical practice.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project represents a formal research agreement between UA and on the other hand Federatie Palliatieve Zorg Vlaanderen. UA provides Federatie Palliatieve Zorg Vlaanderen research results mentioned in the title of the project under the conditions as stipulated in this contract.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Remmen Roy

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project includes: - Wrting the recommendations for Good Practice 'Policy on pandemic influenz', carried out on the basis of the methodology of the Steering group Flemish project guidelines - Collaborating in the development of a scenario for the organisation of primary care in case of pandemic influenza.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Philips Hilde

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project is part of a larger project. Two questions are adressed. What is the current status of training practices for medical specialists in Belgium. A document analysis will be performed. What is known about the quality of traing practices and trainers? For this a systematic review of the literature will be performed.

Researcher(s)

• Promoter: Remmen Roy
• Co-promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The aim of this project is to produce a list of sticking points and barriers to develop and evaluate care pathways. This analysis will be based on the data analysis of the two diabetes projects in Aalst and Leuven. The outcome of this project will be a scenario book with a list of sticking points/barriers, useful for the operationalization of care pathways in future

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project includes: - Wrting the recommendations for Good Practice 'Policy on pandemic influenz', carried out on the basis of the methodology of the Steering group Flemish project guidelines - Collaborating in the development of a scenario for the organisation of primary care in case of pandemic influenza.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Michiels Barbara

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Despite the increasing awareness and need for interprofessional collaboration in health care, only few studies demonstrate its effect. The main purpose of this study is to measure the effect of 'learning to collaborate interprofessionally' on the quality of care for residents of nursing homes. The study is divided into four major parts. The first part is a description of what interprofessional collaboration means and how this skill is taught in educational modules. These interprofessional education modules form the basis of the intervention in this study for this project. The second part is a systematic literature review conducted with the aim to obtain outcomes of interprofessional collaboration as an intervention for chronic geriatric care. Evidence is being searched that may or may not demonstrate the effect of 'learning to collaborate interprofessionally 'on the quality of care and how it is to be measured. In the third part, the aim is to get a description of the existing care (region Antwerp) for residents in nursing homes. The description of the existing care (usual care) is based on the experiences of professionals and residents using focus groups and depth interviews. The description will give us a better idea of how the care is being organized ' interprofessionally' and what the current problems are at work. In the fourth and final part of this project, a pilot for a cluster randomized controlled trial in primary care with one year follow-up is being performed. This experimental study attempts to quantify the effect of interprofessional collaboration as an intervention on the quality of care for residents in a nursing home. This study measures the possible influence of learning to collaborate interprofessionally for professional help providers, the nursing homes and their residents. With SWOT- analyses bottlenecks in interprofessional collaboration will be identified. In addition several outcomes are being registered since the implementation of the ' interprofessional collaboration-intervention'. On residents level a number of indicators are being monitored, for example the fall incidence, quality of life, etc. Also on nursing home level the experiences with 'learning to collaborate interprofessionally' are being registered for example work absenteeism, number of personnel, etc. With this doctoral study project, the aim is to measure the possible influence of learning to collaborate interprofessionally' on the quality of care, expressed in a limited number of outcome parameters and compared with the existing care. The hypothesis is that learning to collaborate interprofessionally can help to increase the quality of care in nursing homes.

Researcher(s)

• Promoter: Van Royen Paul
• Co-principal investigator: Truijen Steven
• Co-promoter: Meulemans Herman

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The overall aim of this project is to inform best practice and harmonise research in end of life care for cancer patients across Europe through comparison and exchange of approaches and experiences in measurements and research priorities.

Researcher(s)

• Promoter: Van Den Eynden Bart
• Co-promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project aims to perform a systematic literature search and appraisal and to find evidence in the medical literatur for medication interventions for chronic heart failure in ambulant care. The studied outcome variables are: cardiovascular and non-cardiovascular mortality, quality of life and number of hospitalisations. The following substances are studied: angiotensin-converting enzyme inhibitors, adrenergic beta-antagonists, Sartanes, Spironolactone, Thiazides, Diuretics, Digitalis, Erythropoietin, Nitrates and calcium channel blockers. The treatment of chronic heart failure is specifically studied for the following three patient groups: elderly (+65 yrs), diabetic patients and patients with renal insufficiency. Also the side effects of the different substances is studied.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

General objectives: To participate with a Flemisch primary care Network in GRACE. Specific objectives: 1. To determine the proportion of bacterial LRTI. 2. To describe the most important bacterial species in LRTI and to determine to what extent they are resistant to antibiotics. 3. To validate the CRB-65 prediction rule to assess the risk on complications in general practice. 4. To review national and international guidelines on lower respiratory tract infections. 5. To assess whether an evidence-based intervention package reduces antibiotic prescribing for community-acquired LRTI.

Researcher(s)

• Promoter: Goossens Herman
• Co-promoter: Coenen Samuel
• Co-promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

Evaluation of a regional complex intervention for diabetes type 2 based on existing health data. The overall objective of this project is to improve the quality of diabetes care and to contribute in this way to the overall health and quality of life of people living with diabetes. In a previous study, regional shared care interventions for diabetes type 2 were developed and implemented. The aim of this research project is to compare the process and outcome results of these interventions with the quality of care in a control region were usual care continued. An economic evaluation will be completed as well. A regional diabetes database using existing data of health insurance companies and clinical laboratories is being build up to answer following research questions: - Is the follow-up of process-parameters better in the intervention than in the usual care regions? - Do the interventions have a significant effect on HbA1c and/or LDL-cholesterol (primary outcome parameters) compared to the usual care region? - What is the direct medical cost per patient in the intervention and usual care regions? - Which avoided costs can be calculated as a result of the interventions compared to usual care region?

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The general aim is to develop guidelines for general practice. Guidelines are followed by general practitioners unless they have practie relevant reasons not to do so. Guidelines are developed step by step: starting up authorgroups, developing clinical questions, draft version of the guideline, assessment by the commission, external experts and local quality groups of GPs. Each year one guideline is started up and one other is finalised. All guidelines are regularly updated and reviewed.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Dirven Kristien

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project aims to perform a systematic literature search and appraisal and to find evidence in the medical literature for medicinal interventions for the symptomatic treatment of pain. Main points of interest for outcome variables: effectiveness, safety , cost efficiency, different galenic forms, different ways of administration, duration of effectiveness, side affects, association of drugs, compliance to therapy. The analgetics that were searched for in detail are: Paracetamol, Acetylsalicyl acid, Tramadol, Morfine, Methadone, Hydromorfone, Oxycodone, Fentanyl, Dextropropoxyfeen, Buprenorfine, Tilidine, Nefopam, transcutane application systems of narcotic analgetics, previously mentioned anti-epileptica (clonazepam, gabapentine, amantadine, carbamazepine, oxcarbazepine) The search did not include (outside the scope): Migraine and all other kinds of headache, Inpatients, Complex regional pain syndrom (CRPS 1 and 2), Angor, Antidepressants (unless indicated for neuropathic pain; unless with proven effectiveness for other indiations), fibromyalgia, NSAID (unless in comparison with other analgetics), spasmolytics for viscerale pain management, malignant pain

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The general aim is to develop guidelines for general practice. Guidelines are followed by general practitioners unless they have practie relevant reasons not to do so. Guidelines are developed step by step: starting up authorgroups, developing clinical questions, draft version of the guideline, assessment by the commission, external experts and local quality groups of GPs. Each year one guideline is started up and one other is finalised. All guidelines are regularly updated and reviewed.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Peremans Lieve
• Co-promoter: Philips Hilde

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

In spite of the growing interest in patient-centredness in medical education, there's still a decline in patient-centredness as students progress through medical school. Several causal factors have been suggested, but there's a lack of research into stimulating and inhibiting factors of patient-centredness in medical students. The aim of this study is to describe the determinants of patient-centredness in medical students, and to measure the effect of communication skills training and hospital internships. A measurement scale is developed in order to study the evolution of patient-centredness in medical students in a cross-sectional and longitudinal design. Focus groups and in-depth interviews will deliver information about the inner development of this important competence.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

For many problems encountered in primary care strong evidence to support management is lacking. In addition there is a problem of implementing evidence-based management in everyday practice. Both lead to sub-optimal patient care and misuse of available resources. Respiratory tract infections are a good example of this (Coenen S. Antibiotics for coughing in general practice [Dissertation]. University of Anwerp 2003). For lower respiratory tract infections (LRTIs) the evidence for the effectiveness of antibiotics is conflicting. Furthermore, the evidence does not allow to identify those patients who would (not) benefit from antibiotic treatment. For otitis media with effusion (OME) antibiotics are of very limited benefit. On the other hand the relevant evidence base on the overall effectiveness of surgery is provided in OME. Here however poor selectivity for referrals by GPs to ENT was documented. The current research project aims to inform the development of interventions to improve the predictive validity of OM referrals and to improve pragmatic choices about the use of antibiotics for all patients with LRTI and for important clinical subgroups of patients with LRTI.

Researcher(s)

• Promoter: Goossens Herman
• Co-promoter: Van Royen Paul
• Fellow: Coenen Samuel

Research team(s)

Project type(s)

• Research Project

Abstract

The aim of this project is to answer two research questions: Is there new evidence after the last literature search on the different guidelines? Does this new evidence change the key messages of the guidelines ? The literature is searched for in three databases: Medline, Embase and the Cochrane Library from 2000 till now. The selected articles are assessed for their quality with standardised checklists. Evidence tables are made and the key messages of the different guidelines are reformulated with the help of GRADE, an instrument for formulating recommendations

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Treatment of diabetes involves complex changes in behaviour and adherence to complicated regimes. Succesful diabetes management requieres that health care professionasl understand patients' attitudes, beliefs and lifestyle. This kind of information can not be accessed by the population based research methods. This study focuses on the individual as a 'longitudinal case study', trying to understand the individual as a whole within their social context and over time. Between april and november 2005 an intensive datacollection (interviews, diary keeping, medical record data, data on health care consultations) will be undertaken with 6 to 8 diabetic patients and their environment. Feasibility of this multimethod data collection will be assessed and structured comparative case analysis will be used to idendify important factors influencing an individuals' health journey.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The aim of this study is to formulate policy recommendations for the quality and organisation of diabetes care, taking into account the severity of disease and associated co-morbidity. In the international literature and existing guidelines, quality indicators and essential preconditions for a hig-quality diagnosis, treatment and follow-up of diabetic patients will be searched for. Also organsation models of optimal diabetes care will be looked for. All relevant literature will be put into evidence tables, and will be assesed critically on quality. The policy recommendations will be assessed by a group of experts.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

This project aims to develop initiatives on improving the collaboration and communication between general practitioners and patients, particularly by an internet based application. Articles and texts, on health prevention will be made available and be published by benevita. Files on health and well-being will be developed, as concepts improving the collaboration and communication between general practitioners and patients. Finally test environments for scientific research will be organised.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Coenen Samuel

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

As preparation for the Belgian consensus meeting on clinical efficacy of medication for complicated hypertension (hypertension with type 2 diabetes, cerebrovascular and heart diseases, chronic kidney disorders), a literature review will be done on clinical studies with the following endpoints: reduction of cardiovascular morbidity and mortality, reduction of renal failure and morbidity, type 2 diabetes morbidity)

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

For many problems encountered in primary care strong evidence to support management is lacking. In addition there is a problem of implementing evidence-based management in everyday practice. Both lead to sub-optimal patient care and misuse of available resources. Respiratory tract infections are a good example of this (Coenen S. Antibiotics for coughing in general practice [Dissertation]. University of Anwerp 2003). For lower respiratory tract infections (LRTIs) the evidence for the effectiveness of antibiotics is conflicting. Furthermore, the evidence does not allow to identify those patients who would (not) benefit from antibiotic treatment. For otitis media with effusion (OME) antibiotics are of very limited benefit. On the other hand the relevant evidence base on the overall effectiveness of surgery is provided in OME. Here however poor selectivity for referrals by GPs to ENT was documented. The current research project aims to inform the development of interventions to improve the predictive validity of OM referrals and to improve pragmatic choices about the use of antibiotics for all patients with LRTI and for important clinical subgroups of patients with LRTI.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Goossens Herman
• Fellow: Coenen Samuel

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

The aim of this project is to assess whether a model of `shared care', coordinated by general practitioners can significantly improve the outcome for patients with type 2 diabetes mellitus. The project will also examine which actions are necessary and effective and will calculate the corresponding care costs. Coordinated primary care teams will be developed, with dieticians, podologists and the diabetes educator as support for the GPs. A shared care program, based on a multidisciplinary care protocol and well-defined tasks and responsibilities, will enable the primary care team to optimalize the care process. The diabetes passport will be a useful instrument for the empowerment of patients. This project also includes collaboration with specialised and hospital care.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

As an experiment, the Belgian Health Care Organization erected a few Palliative day care centers (PDCC). They should increase continuity between in-patient and home care settings and ease the burden of responsibility on the family. PDCC provide facilities for medical, psychological, social and spiritual activities. Their ultimate goal is to guarantee patient's quality of life. Unfortunately, few patients find their way to the PDCC. Are these PDCC unknown among patients' family physician? What are the (dis) advantages of PDCC according to the family physicians? A quantitative study (i.e. postal questionnaire) explores their opinions.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Van Den Eynden Bart

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

In preparation of the consensus meeting of 28th May 2002, a systematic literature review study will be done in the databases of Medline, Cochrane and via links on the website of the National Guideline Clearinghouse. The aim is to summarise the effect of primary and secondary prevention with lipid lowering drugs on coronary heart disease events, coronary heart disease mortality and all cause mortality. Data extraction and quality assessment of all selected references are done by 2 reviewers using a standardized formular. Disagreements are resolved by consensus.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

We expect health workers to be careful in their patient contacts in order to prevent transmission of infectious diseases. One of the possibilities is the influenza vaccination. With this research project we want to study whether this vaccine prevents general practitioners for the symptoms and complications of influenza. Also the carrying of viruses in nose and throat after influenza vaccination will be studied. In a pilot study 30 non-vaccinated general practitioners will be asked to take swabs from their noses and throats several days after contact with a patient who showed signs of influenza infection. They also had to take swabs when they ran a fever (>38°C) in combination with coughing. The results will tell us whether general practitioners carry viruses in nose and throat after contact with patients who are suffering influenza. We also learn when precisely the cultures become positive. In a following study we will compare the virus carrying in a group of 60 vaccinated general practitioners and a non-vaccinated group. Also the factors which influence the virus carrying , will be studied

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

• Primary and interdisciplinary care Antwerp (ELIZA)

Project type(s)

• Research Project

Abstract

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

Acute respiratory tract infections represent a medically, epidemiologically and socio-economically relevant problem. The diagnostic policy in primary health care, following 'coughing' as the reason for encounter, is very specific for this setting: confirm and rule out in a diagnostic landscape with low pretest probability. Which are the arguments used to conduct this policy? How streng are they and which should be used? These research questions will be answered in a partly qualitative (focus-groups) and partly quantitative research design (registration, OSCE test).

Researcher(s)

• Promoter: Van Royen Paul
• Fellow: Coenen Samuel

Research team(s)

Project type(s)

• Research Project

Abstract

The aim of the project is to evaluate the functioning of diabetes experts in local collaboration initiatives, and to improve in this way the care of diabetes type II patients. The role and tasks of the diabetes experts will be assessed. Various interdisciplinary interventions and projects are developped. The outcome as well as the transferability and the generalization of these are studied.

Researcher(s)

• Promoter: Denekens Joke
• Co-promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

This project has the following objectives: Supervision of the realisation of a preventive policy plan for their own region by all the multidisciplinary teams in Flanders. (n=20). Development and execution of the truncus communis of the training for the multidisciplinary teams. Development and execution of the training for the administrator function in the team. Coordination of the whole training program. Evaluation of the formation proces of the loco-regional structures and the functioning of the multidisciplinary teams.

Researcher(s)

• Promoter: Denekens Joke
• Co-promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

Acute respirators tract infections represent a medically, epidemiologically and socio-economically relevant problem. The diagnostic policy in primary health care, following 'coughing' as the reason for encounter, is very specific for this setting: confirm and rule out in a diagnostic landscape with low protest probability. Which are the arguments used to conduct this policy ? How strong are they and which should be used? These research questions will be answered in a partly qualitative (focus-groups), and partly quantitative research design (registration, OSCE test).

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

Acute respiratory tract infections represent a medically, epidemiologically and socio-economically relevant problem. The diagnostic policy in primary health care, following 'coughing' as the reason for encounter, is very specific for this setting: confirm and rule out in a diagnostic landscape with low pretest probability. Which are the arguments used to conduct this policy? How streng are they and which should be used? These research questions will be answered in a partly qualitative (focus-groups) and partly quantitative research design (registration, OSCE test).

Researcher(s)

• Promoter: Van Royen Paul
• Fellow: Coenen Samuel

Research team(s)

Project type(s)

• Research Project

Abstract

Determinants of home/hospital/hospice care for terminally ill patients. Subsequent qualitative research aims to investigate the determining factors of place of care of terminally ill patients by means of focus group discussions. Eight different population groups are organize family care givers (considering sex and place of death of the patient), home care givers (professionals and non-professionals), and social assistents/nurses.

Researcher(s)

• Promoter: Denekens Joke
• Co-promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

The home care for diabetica type II can and must be ameliorated e.g. ootimization of the structure in which the home care is provided. The project draws up an inventory of the part and the tasks of the diabetes expert - such as the facilitation of this care. Methods for adequate interventions are being developed and evaluated. Moreover, transferability and generalization of this project are being analysed.

Researcher(s)

• Promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

Study on the quality of palliative care in a hospice. Subsequent prospective and descriptive survey aims to investigate the needs of care of terminally ill patients as welf as the quality of given care in a hospice. In addition, the reasons of admittions and referrals, as welf as the degree of involvement of general practitioners are studied.

Researcher(s)

• Promoter: Denekens Joke
• Co-promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

The home care for diabetics type II can and must be ameliorated bv e.g. optimization of the structure in which the home care is provided. The project draws up an inventory of the part and the tasks of the diabetes expert - such as the facilitation of this Methods for adequate interventions are being developed and evaluated. Moreover, transferability and generalization of this project are being analysed.

Researcher(s)

• Promoter: Denekens Joke
• Co-promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

In this project we will evaluate the educational situation concerning basic medical skills in the undergraduate course at the University of Antwerp. One cohort of students will be followed during the clinical part of the core curriculum. Five studies will be perforrned to gather data on the intended taught and the learned curriculum using both quantitative and qualitative methods.

Researcher(s)

• Promoter: Denekens Joke
• Co-promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

In this project we will evaluate the educational situation concerning basic medical skills in the undergraduate course at the University of Antwerp. One cohort of students will be followed during the clinical part of the core curriculum. Five studies will be performed to gather data on the intended, taught and the learned curriculum using both quantitative and qualitative methods.

Researcher(s)

• Promoter: Remmen Roy
• Co-promoter: Denekens Joke
• Co-promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

In this study we investigate the expectations of Maroccan girls and boys towards family planning and their actual sexual behaviour This includes:-a study of literature-an interrogation of Maroccan girls and boys in focusgroups- face to face interviews.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Denekens Joke

Research team(s)

Project type(s)

• Research Project

Abstract

Study on the quality of palliative care in a hospice. This prospective and descriptive study will investigate the needs and demands of patients and their quality of care in a palliative hospice. Different elements are studied: the reasons why patients are admitted on and eventually are referred. the factors which determine why the G.P. and the primary health care team is involved or not.

Researcher(s)

• Promoter: Van Royen Paul
• Co-promoter: Denekens Joke

Research team(s)

Project type(s)

• Research Project

Abstract

In this study we investigate patient- and doctor related factors that determine the contraceptive behavior of Moroccan women. This includes : - a study of literature - an interrogation of Moroccan women in Focusgroups - an inquiry of doctors on the field.

Researcher(s)

• Promoter: Denekens Joke
• Co-promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project

Abstract

The aim of the project is : - Tb make a global picture of epidemiological data concerning incidence and prevalence of HIV/AIDS and STD. - Tb investigate the consultationbehaviour of STD-patients : which medical doctors see patients with an STD ? - Tb develop a training for physicians to improve their skills to counsel STD-patients.

Researcher(s)

• Promoter: Denekens Joke
• Co-promoter: Van Royen Paul

Research team(s)

Project type(s)

• Research Project