Research

Research group

Laboratory for Experimental Hematology (LEH)

Expertise

  • Primary cell culture from mouse and human, including immune cells (dendritic cells, macrophages, T-cells) and stem cells (embryonic stem cells, induced pluripotent stem cells, neural stem cells and mesenchymal stem cells). Multi-colour flow cytometric analyses for cellular phenotyping and T-cell analysis. Multi-colour immunocytochemical analyses of cultured (stem) cell populations. Ex vivo genetic engineering of (stem) cell populations using mRNA, plasmid DNA, transposons and lentiviral vectors. Animal models of neuro-inflammation, including the experimental autoimmune encephalomyelitis (EAE) and the cuprizone (CPZ) mouse models applicable for multiple sclerosis research. Cell grafting in brain and spinal cord of rodents. Generation of bone marrow chimeric mice. In vivo non-invasive bioluminescence imaging (monitoring stem cell survival) and magnetic resonance imaging (monitoring white matter lesions). Multi-colour and quantitative immunohistochemical (-fluorescence) analysis of neuro-inflammation.

Projects

You can find here all of the projects that are recorded in the research database of UAntwerp under the name of the academic staff member that acts as a promoter, copromoter or grant holder (a.o. FWO). It concerns only those research projects and mandates that were acquired after an external or internal competition.