Toward anti-herpesviral PROTACs : assessing the challenges for targeted protein degradation on the example of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen

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ChemMedChem - ISSN 1860-7179-21:1 (2026) p. 1-13
Auteur(s)
    Aylin Berwanger, Saskia Catherina Stein, Sarah Brandner, Andreas Martin Kany, Sebastian Heinz, Brigitta Loretz, Claus-michael Lehr, Anna Katharina Herta Hirsch, Frederik Lermyte, Thomas Friedrich Schulz, Martin Empting

Measuring the hydrodynamic radii of peptides and proteins with an unmodified LC-ESI-MS instrument operating in a Taylor dispersion regime

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The analyst - ISSN 0003-2654-150:13 (2025) p. 2829-2836
Auteur(s)
    Jonathan Eisert, Edvaldo Vasconcelos Soares Maciel, Henrik Jensen, Frederik Lermyte

Stability convergence in natural antibodies with ultra-long hypervariable loops

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Communications Biology - ISSN 2399-3642-8:1 (2025) p. 1-14
Auteur(s)
    Marcel Passon, Matja Zalar, Thomas Nehls, Stefaan De Smedt, Frederik Lermyte, Ahmad Reza Mehdipour, Hristo L. Svilenov

Self-packed size-exclusion columns enable versatile high-throughput native, top-down, and ion mobility-mass spectrometry studies on proteins and complexes

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Talanta : the international journal of pure and applied analytical chemistry - ISSN 0039-9140-291 (2025) p. 1-10
Auteur(s)
    Edvaldo Vasconcelos Soares Maciel, Tanja Habeck, Christian Meyners, Frederik Lermyte

Mass spectrometry analysis of chemically and collisionally dissociated molecular glue- and PROTAC-mediated protein complexes informs on disassembly pathways

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Journal of the American Society for Mass Spectrometry - ISSN 1044-0305-36:2 (2025) p. 355-367
Auteur(s)
    Edvaldo V.S. Maciel, Jonathan Eisert, Julian Mueller, Tanja Habeck, Frederik Lermyte