Professor dr Sibyl Anthierens is a social scientist. She is also the co-director of QUALUA (Qualitative Health Research University of Antwerp). Her research focuses on implementation science in primary care both for acute and chronic conditions. Her research reflects the complexity of the health care system and aims at understanding how it works taking context into account. It is clear that evidence alone is not enough to be implemented and that elements of context play a crucial role in translation and adoption of evidence, management strategies or the way that care is delivered. All her areas of application involve drawing together a set of qualitative research methodologies and the so called "mixed methods" where she has extensive expertise and experience in application, but also in development of the methodology itself.
The effectiveness of a blended care program for the discontinuation of benzodiazepines use for sleeping problems in primary care: a clustered randomized trial.
AbstractIntroduction Problematic benzodiazepine use is a global health issue. Although the adverse side effects of longterm use of benzodiazepines are well known, it remains difficult to implement interventions for discontinuation in primary care. Considering the success of blended care for the treatment of sleeping disorders and the support of substance use disorders, evidence suggests that a blended care approach, combining face-to-face consultations with the general practitioner with web-based self-learning by the patient, is beneficial for the discontinuation of chronic benzodiazepine use for primary insomnia in general practice. Therefore, the aim of this study is to evaluate the effectiveness of such an approach for the discontinuation of benzodiazepine and zdrugs ((z-)BZD) use in the long term and evaluate the implementation process. Methods and analysis This study is a multicenter, pragmatic, cluster randomized controlled trial with 1200 patients, included by 120 general practitioners. Allocation to usual or blended care happens at the level of the general practice in a 1:1 ratio using a block randomization system stratified per language. The study population consists of adult primary care patients who have been using (z-)BZD for primary insomnia on a daily basis for at least six months. Primary outcome measure is the proportion of patients that discontinued (z-)BZD at 12 months assessed by toxicological screening for (z-)BZD in urine. Secondary outcomes include discontinuation of (z-)BZD at 6 months, quality of life, and the number of defined daily doses of (z-)BZD prescribed. Data will be collected using a study-specific online platform and analyzed using the intention-to-treat approach. The process of implementing blended care will be evaluated in a nested study.
Scaling-up Packages of Interventions for Cardiovascular disease prevention in selected sites in Europe and Sub-Saharan Africa: An implementation research (SPICES)
AbstractThe overall research objective of the SPICES project is to implement and evaluate a comprehensive CVD prevention and control program in five settings: a rural & semi-urban community in a low-income country (Uganda), middle income (South Africa) and vulnerable groups in three high-income countries (Belgium, France and United Kingdom) as well as to identify and compare the barriers and facilitators across study contexts. The project will be evaluated using a mix of qualitative and quantitative methods. At the beginning of the project, we will conduct baseline assessments including literature reviews, formative studies, household surveys (where feasible) and learn lessons from other projects to understand healthcare and lifestyle practices, barriers, and facilitators. A costeffectiveness and cost benefit analysis will be included. In addition, the teams will conduct site exchanges visits to learn from each other and organise policy dialogues to ensure sustainability and maximise impact of the interventions.
- Promotor: Bastiaens Hilde
- Co-promotor: Anthierens Sibyl
- Co-promotor: Van Royen Paul
- Co-promotor: Van geertruyden Jean-Pierre
Antibiotics General Practitioner Survey
AbstractTo ensure that future policy initiatives best match the experience and needs of general practitioners, EBPracticeNet, the reference platform for Evidence-Based Practice for all Belgian healthcare providers, together with the academic centers for general practice of UAntwerp and ULiège, is launching the Antibiotics General Practitioner Survey (Antibiotic GPS). We receive support for this in Flanders from all universities and Domus Medica. In the Antibiotics GPS (Antibiotics General Practitioner Survey) general practitioners can indicate which actions, instruments and initiatives they find useful in the fight against antimicrobial resistance. This questionnaire assesses experiences with regard to the prescription of antibiotics, current policy initiatives, supporting instruments, (rapid) tests, guidelines, etc. for the effective use of antibiotics in common infections. The survey also asks what lessons we can draw from the corona crisis that are relevant for antibiotic policy. The results will be used to set up new interventions and to guide Belgian AMR policy.
The effect of implementing C-reactive protein point-of-care testing for respiratory tract infections on antibiotic prescribing: a mixed methods study in out-of-hours primary care.
AbstractBACKGROUND: Antibiotic consumption in Belgium is one of the highest in Europe. Infections are the number one reason to consult in out-of-hours (OOH) primary care, and subsequently antibiotics are one of the most prescribed medications. C-reactive protein point-of-care testing with acute respiratory infections could help general practitioners (GPs) to reduce antibiotic prescribing in OOH care and is currently used in different European countries in this setting. The implementation of CRP POCT in Belgian OOH care has not been studied before. RESEARCH QUESTION: Does the implementation of (CRP POCT) in Belgian OOH care reduce antibiotic prescribing for respiratory tract infections (RTIs) and is implementation feasible and acceptable for GPs and patients? OBJECTIVE: To determine the effects on antibiotic prescribing for acute RTI and to assess the feasibility and acceptability when implementing CRP POCT in Belgian OOH primary care. METHOD: Antibiotic prescribing quality at the level of a General Practitioners Cooperative (GPC) will be assessed before the start of the implementation of CRP POCT using antibiotic prescribing quality indicators and will be compared with other GPCs. This will be used during PDSA (plan-do-study-act) cycle(s) as a quantitative indicator of antibiotic prescribing quality improvement. Alongside a qualitative interview study with GPs and patients on the acceptability and feasibility of implementing CRP POCT in OOH primary care will be performed.
- Promotor: Anthierens Sibyl
Exploring needs and expectations of patients towards patient participation in their own care
AbstractWithin the framework of the Center of Excellence Patients Participation, the White Yellow Cross (WGK) Flanders wants to explore the needs and expectations of patients in relation to their own involvement in care. The central objective of the Center of Excellence Patients Participation is to create patient participation tailored to each patient within home care. Gaining insight into the needs, expectations, perceptions and experiences of patients with regard to participation in care forms an important basis for further exploration of patient participation in practice. With this research project we want to gain insight into what makes patients want to participate more or less into their care. These insights can lead to the development of methodologies and strategies that allow care providers to detect and identify the participation needs of their individual patients. This research project starts from the perspective of the patient. The basis of the research design is what matters to the patient and not what we as professionals think that matters to the patient. That is why an inductive qualitative research methodology is chosen in which the experiences and the story of the patient form the basis of our research. This research design is aimed at gaining insight into relevant elements that play a role in the needs of patients to participate in their care
- Promotor: Anthierens Sibyl