Cardiovascular Diseases search menu search content Aortic Valve Disease Transcatheter Aortic Valve Implantation Transcatheter valve implantation for aortic stenosis is an important cardiologic research topic. The department of Cardiology of the Antwerp University Hospital is a pioneer in this type o…

Ilse Luyckx senior researcher Research Ilse Luyckx Research team Medical Genetics (MEDGEN) Expertise Projects: • Unravelling the pathological key events underlying SMAD6-deficiency in patients with bicuspid aortic valve-related aortopathy • Unravelling the genetic architecture of (bicuspid aorti…

Wilhelm Mistiaen emeritus occasionele opdracht Publicaties Wilhelm Mistiaen Surgical aortic valve replacement in cancer survivors with severe symptomatic aortic valve disease : a retrospective single-center observational study Bron Cancers - ISSN 2072-6694-17:20 (2025) p. 1-17 Auteur(s) Ivo Deblier,…

Wilhelm Mistiaen emeritus occasional assignment Research Wilhelm Mistiaen Research team Expertise Retrospective file investigation of 2,500 patients underoing aortic valve replacement with focus on short and long-term complications (cardiovascular, renal, pulmonary and neurologic) with predictors Li…

Lut Van Laer associate professor Research Lut Van Laer Research team Medical Genetics (MEDGEN) Expertise My expertise is situated within cardiogenetics, more specifically within molecular cardiogenetics. Cardiogenetics include the following disorders: thoracic aortic aneurysm and dissection, primary…

Silke Peeters unpaid staff Research Silke Peeters Research team Medical Genetics (MEDGEN) Expertise Our research is focused on the elucidation of the genetic mechanisms causing congenital anomalies and heritable connective tissue disorders with focus on cardiovascular -and growth disorders IPSC-chon…

Bart Loeys full research professor Research Bart Loeys Research team Medical Genetics (MEDGEN) An induced pluripotent stem cell-derived aorta-on-a-chip platform for Loeys-Dietz syndrome modeling. 01/11/2025 - 31/10/2029 Abstract Thoracic aortic aneurysm (TAA) refers to progressive enlargement of the…

Aline Verstraeten associate research professor Research Aline Verstraeten Research team Medical Genetics (MEDGEN) Expertise I commit to doing (functional) genomics research in the field of connective tissue disorders, most prominently thoracic aortic aneurysm and dissection as well as skeletal dyspl…

Josephina Meester assistant professor - postdoc researcher FWO Research Josephina Meester Research team Medical Genetics (MEDGEN) Expertise I am currently doing research in the field of skeletal dysplasia and thoracic aortic aneurysm and dissection. These two groups of diseases are related in the co…

Amira Bousbaa predoc researcher FWO Research Amira Bousbaa Research team Medical Genetics (MEDGEN) An induced pluripotent stem cell-derived aorta-on-a-chip platform for Loeys-Dietz syndrome modeling. 01/11/2025 - 31/10/2029 Abstract Thoracic aortic aneurysm (TAA) refers to progressive enlargement of…

Wilhelm Mistiaen emeritus occasional assignment Publications Wilhelm Mistiaen Surgical aortic valve replacement in cancer survivors with severe symptomatic aortic valve disease : a retrospective single-center observational study Source Cancers - ISSN 2072-6694-17:20 (2025) p. 1-17 Author(s) Ivo Debl…

Lynn Roth tenure track docent Publicaties Lynn Roth The olive polyphenol hydroxytyrosol enhances autophagy and heme oxygenase-1 expression in aortic endothelial cells and reduces arterial stiffness ex vivo Bron Planta medica: natural products and medicinal plant research - ISSN 0032-0943- (2025) p. …

Cédric Neutel postdoc mandaat FWO Publicaties Cédric Neutel The olive polyphenol hydroxytyrosol enhances autophagy and heme oxygenase-1 expression in aortic endothelial cells and reduces arterial stiffness ex vivo Bron Planta medica: natural products and medicinal plant research - ISSN 0032-0943- …

Medical Genetics search menu search content Projects Ongoing projects An induced pluripotent stem cell-derived aorta-on-a-chip platform for Loeys-Dietz syndrome modeling. 01/11/2025 - 31/10/2029 Abstract Thoracic aortic aneurysm (TAA) refers to progressive enlargement of the thoracic aorta. It often…

Irene Valdivia Callejon predoc researcher FWO Research Irene Valdivia Callejon Research team Medical Genetics (MEDGEN) Investigating thoracic aortic aneurysm pathogenesis at single-cell resolution. 01/11/2022 - 31/10/2026 Abstract Thoracic aortic aneurysm (TAA) is an abnormal widening of the aorta i…

Bernard Paelinck assistant professor Research Bernard Paelinck Research team Medical Genetics (MEDGEN) Clinical and (patho)genetic study of bicuspid aortic valve and associated aortic aneurysm. 01/01/2012 - 31/12/2015 Abstract The general aim of this project is to gain insight into the clinical cour…

Justine Verbiest doctoral scholarship holder Research Justine Verbiest Research team Medical Genetics (MEDGEN) Elucidating the TGFß paradox in aortic aneurysmal disease: unveiling the role of endothelial cells and nitric oxide. 01/11/2025 - 31/10/2028 Abstract Impaired TGFß signaling is a defining…

Medical Genetics search menu search content Research topics Research topics The research focus of MEDGEN can broadly be defined as the elucidation of the genetic mechanisms causing congenital anomalies and heritable connective tissue disorders with focus on cardiovascular, growth and osteoarticular …

Joke Durnez onbezoldigd medewerker Publicaties Joke Durnez Retrograde Type A aortic dissection 48 Hours after TEVAR in a Patient with a delayed diagnosis of vascular Ehlers-Danlos syndrome Bron Aorta : official journal of the Aortic Institute at Yale-New Haven Hospital - ISSN 2325-4637-10:03 (2022) …

Johan Bosmans gewoon hoogleraar Publicaties Johan Bosmans Clinical validation of predictive procedural planning software in a real-world TAVI population Bron Catheterization and cardiovascular interventions - ISSN 1522-1946- (2025) p. Auteur(s) Anne-Sophie Claes, Bernard Paelinck, Inez Rodrigus, Tom…

Lotte Van Den Heuvel onbezoldigd medewerker Publicaties Lotte Van Den Heuvel An exploration of alternative therapeutic targets for aortic disease in Marfan syndrome Bron Drug discovery today - ISSN 1359-6446-29:7 (2024) p. 1-12 Auteur(s) Lotte Van Den Heuvel, Silke Peeters, Josephina Meester, Paul J…

Inez Rodrigus associate professor Research Inez Rodrigus Research team Antwerp Surgical Training, Anatomy and Research Centre (ASTARC) Expertise Endocarditis: clinical expertise - participation in European registry New techiques in aortic and mitral valve surgery: clinical expertise minimal invasive…

Ivanna Fedoryshchenko predoc researcher FWO Research Ivanna Fedoryshchenko Research team Medical Genetics (MEDGEN) Towards patient-specific aorta-on-a-chip models for thoracic aortic aneurysm and dissection. 01/11/2023 - 31/10/2027 Abstract Thoracic aortic aneurysm (TAA) denotes a progressive enlarg…

Wendy Dewals onbezoldigd medewerker Publicaties Wendy Dewals Arterial aneurysm and dissection : toward the evolving phenotype of Tatton-Brown-Rahman syndrome Bron Journal of medical genetics - ISSN 0022-2593-61:9 (2024) p. 870-877 Auteur(s) Vicken Totten, Gisela Teixido-Tura, Fermina Lopez-Grondona,…

Bart Loeys Starting Grant 2012 Bicuspid Related Aortopathy, a Vibrant Exploration (BRAVE) Bicuspid aortic valve, a heart valve with only two leaflets instead of three, is the most common congenital heart defect with an estimated prevalence of about 1-2%. The heart defect often remains asymptomatic b…