We study the relative importance of different exposure routes and the effects of environmental conditions on the bioavailability, accumulation, and toxicity of trace metals and other priority and newly emerging organic micro-contaminants. The field also includes nano-, micro-, and macro-particles such as plastics. Studies are aquatic and terrestrial, field and laboratory-based, in vivo, in vitro, and in silico. It includes the development of dynamic integrated models of accumulation and toxicity of micro-contaminants under different environmentally relevant exposure scenarios with mixtures of contaminants.

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