Superconducting electronics is crucial for a broad spectrum of applications, ranging from highly sensitive biomagnetic measurements of the human body to wideband satellite communications. The ever desired miniaturization and portability of such devices requires the fabrication and behavioral characterization of ultra-small superconducting circuits. Recent advances have enabled controllable growth of crystalline atomically thin (quasi 2D) superconductors, that harbor rich fundamental physics due to quantum confinement of both electrons and phonons, interaction with a substrate, non-trivial effects of strain and gating, etc., and thus hold promise for electronic, magnetic and optical properties that are otherwise unattainable. In other words, ultrathin superconductors can be the base for a new generation of ultra-low power and highly sensitive electronics, with more functionalities than the previous designs. The groundbreaking goal of this project is to enable the exploratory search for those functionalities, by developing multiscale simulations of atomically thin superconducting circuits - starting from ab initio information on electronic and vibronic changes at monolayer thicknesses, then revealing the role of the substrate, intercalants, electric gating, etc. on superconductivity in selected materials, towards simulations of nano-patterned micron-scale circuits, using advanced current-voltage-magnetic field characterization with ab initio parametrization.