Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)

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Frontiers in molecular medicine - ISSN 2674-0095-3 (2024) p. 1-19
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A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis

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The New England journal of medicine - ISSN 0028-4793-390:6 (2024) p. 497-509
Auteur(s)
    Stephen A. Harrison, Pierre Bedossa, Cynthia D. Guy, Jörn M. Schattenberg, Rohit Loomba, Rebecca Taub, Dominic Labriola, Sam E. Moussa, Guy W. Neff, Mary E. Rinella, Quentin M. Anstee, Manal F. Abdelmalek, Zobair Younossi, Seth J. Baum, Sven Francque, Michael R. Charlton, Philip N. Newsome, Nicolas Lanthier, Ingolf Schiefke, Alessandra Mangia, Juan M. Pericàs, Rashmee Patil, Arun J. Sanyal, Mazen Noureddin, Meena B. Bansal, Naim Alkhouri, Laurent Castera, Madhavi Rudraraju, Vlad Ratziu, Christophe Van Steenkiste

Therapeutic management of metabolic dysfunction associated steatotic liver disease

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United European gastroenterology journal - ISSN 2050-6406- (2024) p. 1-10
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The ubiquitin-like modifier FAT10 is induced in MASLD and impairs the lipid-regulatory activity of PPARα

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Metabolism: clinical and experimental - ISSN 0026-0495-151 (2024) p. 1-14
Auteur(s)
    Ludivine Clavreul, Lucie Bernard, Alexia K. Cotte, Nathalie Hennuyer, Cyril Bourouh, Claire Devos, Audrey Helleboid, Joel T. Haas, An Verrijken, Celine Gheeraert, Bruno Derudas, Loic Guille, Julie Chevalier, Jerome Eeckhoute, Emmanuelle Vallez, Emilie Dorchies, Luc Van Gaal, Guillaume Lassailly, Sven Francque, Bart Staels, Rejane Paumelle

A multisociety Delphi consensus statement on new fatty liver disease nomenclature

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Annals of Hepatology - ISSN 1665-2681-29:1 (2024) p. 1-15
Auteur(s)
    Mary E. Rinellaa, Jeffrey V. Lazarusb, Vlad Ratziud, Sven Francque, Arun J. Sanyalg, Fasiha Kanwalh, Diana Romerob, Manal F. Abdelmalekj, Quentin M. Ansteek, Juan Pablo Arabm, Marco Arreseo, Ramon Batallerq, Ulrich Beuersr, Jerome Boursiers, Elisabetta Bugianesit, Christopher D. Byrneu, Graciela E. Castro Narrop, Abhijit Chowdhuryy, Helena Cortez-Pintoaa, Donna R. Cryerab, Kenneth Cusiac, Mohamed El-Kassasad, Samuel Kleinae, Wayne Eskridgeaf, Jiangao Fanag, Samer Gawriehah, Cynthia D. Guyai, Stephen A. Harrisonaj, Seung Up Kimak, Bart G. Kootal, Marko Korenjakam, Kris Kowdleyan, Florence Lacailleao, Rohit Loombaap, Robert Mitchell-Thainaq, Timothy R. Morganaran, Elisabeth E. Powell, Michael Roden, Manuel Romero-Gomez, Marcelo Silvaba, Shivaram Prasad Singhbb, Silvia C. Sookoiano, C. Wendy Spearmanbe, Dina Tiniakosk, Luca Valentibg, Miriam B. Vosbi, Vincent Wai-Sun Wongbj, Stavra Xanthakosbk, Yusuf Yilmazbl, Philip N. Newsome