Jun Xie doctoraatsbursaal Onderzoek Jun Xie Onderzoeksgroep Veterinaire fysiologie en biochemie SAVAGE (SAVe A Genome), in vitro gametogenese voor preservatie van genetica. 01/10/2024 - 30/09/2028 Abstract De aarde wordt geconfronteerd met ongekende uitstervingsniveaus, ook wel "het zesde uitsterven…

Julia Di Stefano Research Julia Di Stefano Research team Laboratory for Experimental Hematology (LEH) Modulation of astrocyte activation in murine iPSC-derived neurospheroids. 01/01/2023 - 31/12/2023 Abstract Neurospheroids cultured from induced pluripotent stem cells (iPSC) represent an important r…

Amira Bousbaa doctoral scholarship holder Research Amira Bousbaa Research team Medical Genetics (MEDGEN) Pushing boundaries in Loeys-Dietz syndrome research through aorta-on-a-chip development. 01/10/2023 - 30/09/2027 Abstract Thoracic aortic aneurysm (TAA) denotes a progressive enlargement of our b…

Pauline De Kinderen predoc researcher FWO Research Pauline De Kinderen Research team Medical Genetics (MEDGEN) The study and therapeutic targeting of endoplasmic reticulum stress in hereditary chondrodysplasias. 01/11/2022 - 31/10/2026 Abstract Chondrodysplasias refer to a large and heterogeneous gr…

Aline Verstraeten associate research professor Research Aline Verstraeten Research team Medical Genetics (MEDGEN) Expertise I commit to doing (functional) genomics research in the field of connective tissue disorders, most prominently thoracic aortic aneurysm and dissection as well as skeletal dyspl…

Melanie Perik unpaid staff Publications Melanie Perik From silence to surge : illuminating the stealthy threat of aneurysms and dissections with the aid of cell models and insights into the genetic architecture Source Antwerp, University of Antwerp, Faculty of Medicine and Health Sciences, 2024,269 …

Silke Peeters postdoc researcher FWO Publications Silke Peeters An exploration of alternative therapeutic targets for aortic disease in Marfan syndrome Source Drug discovery today - ISSN 1359-6446-29:7 (2024) p. 1-12 Author(s) Lotte Van Den Heuvel, Silke Peeters, Josephina Meester, Paul J. Coucke, B…

Maxim van Hoek predoc researcher FWO Research Maxim van Hoek Research team VIB CMN - Microglia and Inflammation in Neurological Disorders (MIND) lab Defining the impact of the iPSC-derived human microglial secretome in Alzheimer's disease employing ER-mediated TurboID proximity labelling in vivo. 01…

Anne Hebert predoc researcher FWO Research Anne Hebert Research team Medical Genetics (MEDGEN) Using human iPSC-derived models to investigate the divergent pathomechanisms underlying biglycan-related Meester-Loeys syndrome and X-linked spondyloepimetaphyseal dysplasia. 01/11/2023 - 31/10/2025 Abstra…

Elise Van Breedam senior researcher Publications Elise Van Breedam Varicella-zoster virus recapitulates its immune evasive behaviour in matured hiPSC-derived neurospheroids Source Frontiers in immunology - ISSN 1664-3224-15 (2024) p. 1-19 Author(s) Jonas Govaerts, Elise Van Breedam, Sarah De Beuckel…

Julia Di Stefano Onderzoek Julia Di Stefano Onderzoeksgroep Laboratorium voor Experimentele Hematologie (LEH) Modulatie van astrocyt activering in muis iPSC-afgeleide neurosferoïden. 01/01/2023 - 31/12/2023 Abstract Neurosferoïden gekweekt uit geïnduceerde pluripotente stamcellen (iPSC) vormen ee…

Silke Peeters postdoc researcher FWO Research Silke Peeters Research team Medical Genetics (MEDGEN) Expertise Our research is focused on the elucidation of the genetic mechanisms causing congenital anomalies and heritable connective tissue disorders with focus on cardiovascular -and growth disorders…

Josephina Meester assistant professor - postdoc researcher FWO Research Josephina Meester Research team Medical Genetics (MEDGEN) Expertise I am currently doing research in the field of skeletal dysplasia and thoracic aortic aneurysm and dissection. These two groups of diseases are related in the co…

Aleksandra Nijak unpaid staff Publications Aleksandra Nijak Generation of four distinct isogenic cell lines with truncating variants in I-band or A-band titin Source Stem cell research - ISSN 1873-5061-81 (2024) p. 1-6 Author(s) Hanne Boen, Bert Vandendriessche, Jolien Schippers, Laura Rabaut, Aleks…

Siebe Van Calster predoc researcher FWO Research Siebe Van Calster Research team Laboratory for Experimental Hematology (LEH) Functional and molecular profiling of immune-competent neurospheroids under stroke-like conditions. 01/11/2023 - 31/10/2024 Abstract Due to the enormous impact of stroke on t…

Amira Bousbaa doctoraatsbursaal Onderzoek Amira Bousbaa Onderzoeksgroep Medische Genetica (MEDGEN) Grensverleggend onderzoek naar het Loeys-Dietz syndroom door middel van aorta-on-a-chip creatie. 01/10/2023 - 30/09/2027 Abstract Een thoracaal aorta-aneurysma (TAA) is een progressieve vergroting van …

Dorien Schepers postdoc researcher FWO Publications Dorien Schepers Decoding the genetic puzzle of inherited cardiac arrhythmias : insights from molecular autopsy, genetic profiling and iPSC-derived cardiomyocyte modelling Source Antwerp, University of Antwerp, Faculty of Medicine and Health Science…

Rita Cacace external postdoc researcher Research Rita Cacace Research team VIB CMN - Genetics of Alzheimer’s Disease Expertise Dr. Rita Cacace holds a PhD in biomedical sciences and studies Alzheimer’s disease and related dementias. Her work focuses on understanding the functional consequences o…

Medical Genetics search menu search content Projects Ongoing projects Elucidating the TGFß paradox in aortic aneurysmal disease: unveiling the role of endothelial cells and nitric oxide. 01/11/2024 - 31/10/2025 Abstract Impaired TGFß signaling is a defining feature of thoracic aortic aneurysm and …

Bieke Bekaert postdoc researcher FWO Research Bieke Bekaert Research team Peripheral Neuropathies Group Expertise My PhD research project focused on CRISPR/Cas9 gene editing in the mouse/human germline and human pluripotent disease stem cell models targeting genes related to infertility. Currently, …

Aline Verstraeten hoofddocent Onderzoek Aline Verstraeten Onderzoeksgroep Medische Genetica (MEDGEN) Expertise Mijn onderzoek omvat (functional) genomics projecten in het veld van bindweefselaandoeningen, meer bepaald thoracale aorta aneurysma's en dissecties alsook skeletale dysplasieën. Hoewel be…

Pauline De Kinderen predoc mandaat FWO Onderzoek Pauline De Kinderen Onderzoeksgroep Medische Genetica (MEDGEN) De studie en therapeutische targeting van endoplasmatisch reticulum stress bij erfelijke chondrodysplasieën. 01/11/2022 - 31/10/2026 Abstract De term chondrodysplasieën verwijst naar een…

Peter Ponsaerts Research Peter Ponsaerts Research team Laboratory for Experimental Hematology (LEH) Expertise Primary cell culture from mouse and human, including immune cells (dendritic cells, macrophages, T-cells) and stem cells (embryonic stem cells, induced pluripotent stem cells, neural stem ce…

Silke Peeters postdoc mandaat FWO Publicaties Silke Peeters An exploration of alternative therapeutic targets for aortic disease in Marfan syndrome Bron Drug discovery today - ISSN 1359-6446-29:7 (2024) p. 1-12 Auteur(s) Lotte Van Den Heuvel, Silke Peeters, Josephina Meester, Paul J. Coucke, Bart Lo…

Pauline De Kinderen predoc mandaat FWO Publicaties Pauline De Kinderen IPSC reprogramming of two patients with spondyloepiphyseal dysplasia congenita (SEDC) Bron Stem cell research - ISSN 1873-5061-69 (2023) p. 1-5 Auteur(s) Pauline De Kinderen, Laura Rabaut, Melanie Perik, Silke Peeters, Peter Pons…