13/10/2021 - Tommaso (ESR #6)

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The use of animals in experiments is something very important to all of us, scientists or not.  In the past decades, a lot of progress has been made to replace lab animals where possible and a lot of work is still ongoing nowadays. In general, scientists operate following the rules known as the "3Rs", which are hierarchically organized:

  • Replacement = Use a model that is not an animal if possible
  • Reduction = Use the least amount of animal labs that still allows getting significant data
  • Refinement = Give the animals the best conditions possible

In the image here you find a gross representation of the proportion of the animals used in scientific research and here there is a table with the exact percentages [1].

  • Mice: 2,92%
  • Fish: 14,61%
  • Rats: 5,05%
  • Birds: 4,21%
  • Other mammals: 2,36%
  • Reptiles : 0,003%
  • Amphibians: 0,28%
  • Primates: 0,09%
  • Cats: 0,005%
  • Dogs: 0,13%
  • Horses: 0,30%

References:

  1. Robinson et al. (2019), The current state of animal models in research: A review, International Journal of surgery, https://doi.org/10.1016/j.ijsu.2019.10.015