Welcome

The research group Veterinary Physiology and Biochemistry concentrates its academic scientific research within the Gameter Research Center, a platform where the female gamete, the embryo and the early embryonic development have a central position.
 
More specifically, (environmental) factors are studied that might have a (negative) influence on oocyte developmental capacity and embryo growth, including possible consequences during pregnancy, for the newborn and in later life. Most of this research is based on self-developed ''high throughput'' in vitro models, such as bovine, murine and zebrafish in vitro models for the study of follicular development, oocyte prematuration and maturation, fertilization and in vitro embryo culture.

Recent publications

Evaluating complex mixtures in the zebrafish embryo by reconstituting field water samples : a metal pollution case study

Michiels Ellen, Vergauwen Lucia, Hagenaars An, Fransen Erik, Van Dongen Stefan, Van Cruchten Steven, Bervoets Lieven, Knapen Dries, International journal of molecular sciences - ISSN 1661-6596 - 18:3(2017), p. 1-16 

Maternal metabolic stress may affect oviduct gatekeeper function

Jordaens Lies, Van Hoeck Veerle, Maillo Veronica, Gutierrez-Adan Alfonso, Marei Waleed, Vlaeminck Bruno, Thys Sofie, Sturmey Roger G.s., Bols Peter, Leroy Jo, Reproduction / Society for the Study of Fertility [Cambridge] - ISSN 1470-1626 - (2017), p. 1-30

The effect of a negative energy balance status on β-carotene availability in serum and follicular fluid of nonlactating dairy cows

De Bie Jessie, Langbeen An, Verlaet Annelies, Florizoone F., Immig I., Hermans Nina, Fransen Erik, Bols Peter, Leroy Jo, Journal of dairy science - ISSN 0022-0302 - 99:7(2016), p. 5808-5819 

Effect of nutritionally induced hyperlipidaemia on in vitro bovine embryo quality depends on the type of major fatty acid in the diet

Marei Waleed, Arias Alvarez Maria, Van Hoeck Veerle, Gutierrez-Adan Alfonso, Bols Peter, Leroy Jo, Reproduction, fertility and development - ISSN 1031-3613 - (2016), p. 1-33 

 

 

 


Research Mission and Members
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Zebrafishlab
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Research seminar

“Fatty acid metabolism in cumulus oocyte complexes: basic concepts and the consequences of an altered fatty acid micro-environment”

Dr. Svetlana Uzbekova 

INRA – French National Institute for Agriculture 

Physiologie de la Reproduction et des Comportements

Sponsered by the Flemish Government

The Gamete Research Centre research team would like to invite you to their seminar for young researchers on Tuesday 16th of May (9 a.m. – 1 p.m.) in the U-building, Campus Drie Eiken.

Invtation and Program

Contact

Prof. Dr. Peter Bols
(head research unit)
Campus Drie Eiken
U 0.09
Universiteitsplein 1
B-2610 Wilrijk
Tel. 0032 3 265 23 97
Tel. 0032 3 265 23 93
Peter.Bols@uantwerp.be
Events


1    More activities and calendar

Key publications

Bovine in vitro reproduction models can contribute to the development of (female) fertility preservation strategies

Langbeen An, De Porte Hannelore F.M., Bartholomeus Esther, Leroy Jo, Bols Peter, Theriogenology 84:4(2015), p. 477-489

Morphologic characterization of isolated bovine early preantral follicles during short-term individual in vitro culture

Jorssen Ellen, Langbeen An, Marei Waleed, Fransen Erik, De Porte H.F.M., Leroy Jo, Bols Peter, Theriogenology 84(2015),p. 301-311

Nutrition and maternal metabolic health in relation to oocyte and embryo quality : critical views on what we learned from the dairy cow model

Leroy Jo, Valckx Sara, Jordaens Lies, De Bie Jessie, Desmet Karolien, Van Hoeck Veerle, Britt Jack H., Marei Waleed, Bols Peter, Reproduction, fertility and development 1031-3613-(2015),p. 1-28

Elevated non-esterified fatty acid concentrations during in vitro murine follicle growth alter follicular physiology and reduce oocyte developmental competence 

Valckx SD, Van Hoeck V, Arias-Alvarez M, Maillo V, Lopez-Cardona AP, Gutierrez-Adan A, Berth M, Cortvrindt R, Bols PE, Leroy JL, Fertility and Sterility, Volume 102, Issue 6, December 2014, Pages 1769–1776

PFOS affects posterior swim bladder chamber inflation and swimming performance of zebrafish larvae

Hagenaars A, Stinckens E, Vergauwen L, Bervoets L, Knapen D, Aquat Toxicol. 2014 Dec;157:225-35

The potential of AOP networks for reproductive and developmental toxicity assay development

Knapen D, Vergauwen L, Villeneuve DL, Ankley GT, Reprod Toxicol. 2015 Aug 15;56:52-5

A high throughput passive dosing format for the Fish Embryo Acute Toxicity test

Vergauwen L, Schmidt SN, Stinckens E, Maho W, Blust R, Mayer P, Covaci A, Knapen D, Chemosphere. 2015 Nov;139:9-17